(Q28478288)

English

Genetic knockdown and pharmacological inhibition of parasite multidrug resistance transporters disrupts egg production in Schistosoma mansoni

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scholarly article

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Genetic knockdown and pharmacological inhibition of parasite multidrug resistance transporters disrupts egg production in Schistosoma mansoni (English)

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infectious disease

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multiple drug resistance

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Schistosoma mansoni

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1 reference

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author name string

Ravi S Kasinathan

1

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William M Morgan

2

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Robert M Greenberg

3

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language of work or name

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publication date

December 2011

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PLoS Neglected Tropical Diseases

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5

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12

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e1425

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copyright license

Creative Commons Attribution 4.0 International

6 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

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Schistosoma haematobium treatment in 1-5 year old children: safety and efficacy of the antihelminthic drug praziquantel

1 reference

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19 March 2017

The Syk kinase SmTK4 of Schistosoma mansoni is involved in the regulation of spermatogenesis and oogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

19 March 2017

Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

19 March 2017

Analyzing real-time PCR data by the comparative C(T) method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

19 March 2017

ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

19 March 2017

Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

19 March 2017

Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

7 April 2017

The "specific" P-glycoprotein inhibitor Tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Pharmacology and potential physiological significance of schistosome multidrug resistance transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Schistosomiasis elimination: lessons from the past guide the future

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29 September 2017

Applications for profiling the schistosome transcriptome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Drug resistance mechanisms in helminths: is it survival of the fittest?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Towards an understanding of the mechanism of action of praziquantel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

The unacknowledged impact of chronic schistosomiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Genuine functions of P-glycoprotein (ABCB1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Protocols for gene silencing in schistosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Schistosoma mansoni: TGF-beta signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

TGF-beta signaling controls embryo development in the parasitic flatworm Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Reversal of multidrug resistance by 4-chloro-N-(3-((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)phenyl)benzamide through the reversible inhibition of P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Praziquantel for the treatment of schistosomiasis: its use for control in areas with endemic disease and prospects for drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Multidrug resistance in parasites: ABC transporters, P-glycoproteins and molecular modelling

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Are Ca2+ channels targets of praziquantel action?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

A new description of the reproductive system of Schistosoma mansoni (Trematoda: Schistosomatidae) analyzed by confocal laser scanning microscopy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

P-glycoprotein: from genomics to mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

P-glycoprotein in helminths: function and perspectives for anthelmintic treatment and reversal of resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement

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29 September 2017

1 reference

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29 September 2017

Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells

1 reference

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29 September 2017

In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576.

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29 September 2017

A role for P-glycoprotein in regulating cell death

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29 September 2017

Multiple physiological functions for multidrug transporter P-glycoprotein?

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29 September 2017

Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Two Schistosoma mansoni cDNAs encoding ATP-binding cassette (ABC) family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Praziquantel: mechanisms of anti-schistosomal activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Dosage, timing, and route of administration of cyclosporin A and nonimmunosuppressive derivatives of dihydrocyclosporin A and cyclosporin C against Schistosoma mansoni in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Schistosoma mansoni: chemotherapy of infections of different ages

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

29 September 2017

Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil

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29 September 2017

Schistosomiasis in Africa: an emerging tragedy in our new global health decade

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2 June 2018

Schistosome egg granulomas and hepatic expression of TNF-alpha are dependent on immune priming during parasite maturation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232217

2 June 2018

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

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2 June 2018

Effects of praziquantel on different developmental stages of Schistosoma mansoni in vitro and in vivo.

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2 June 2018

Anti-schistosomal activity of cyclosporin A: studies on murine spleen cells and the influence of a cyclosporin antagonist on resistance to infection.

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2 June 2018

The schistosome excretory system: a key to regulation of metabolism, drug excretion and host interaction.

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21 January 2018

Multidrug resistance-associated protein MRP-1 regulates dauer diapause by its export activity in Caenorhabditis elegans

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https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001425

21 January 2018

Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001425

21 January 2018

Ivermectin imposes selection pressure on P-glycoprotein from Onchocerca volvulus: linkage disequilibrium and genotype diversity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001425

21 January 2018

Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein.

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21 January 2018

Expression of ATP-binding cassette multidrug transporters in the giant liver fluke Fasciola gigantica and their possible involvement in the transport of bile salts and anthelmintics.

1 reference

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21 January 2018

Correlation between loss of efficacy of macrocyclic lactone heartworm anthelmintics and P-glycoprotein genotype

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https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001425

21 January 2018

An update on P-glycoprotein and drug resistance in Schistosoma mansoni

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21 January 2018

Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment

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https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001425

21 January 2018

In vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms.

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21 January 2018

Optimizing gene suppression in schistosomes using RNA interference.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001425

21 January 2018

The embryonic development of Schistosoma mansoni eggs: proposal for a new staging system.

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21 January 2018

Cyclosporin A enhances the pulmonary granuloma response induced by Schistosoma mansoni eggs

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporins: lack of correlation between antischistosomal properties and inhibition of cyclophilin isomerase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22163059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/22163059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of cyclosporin A on the course of murine infection by Schistosoma mansoni

1 reference

https://pubmed.ncbi.nlm.nih.gov/22163059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22163059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PNTD.0001425

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https://api.fatcat.wiki/v0/release/cjtybpnovvejdlzdsejiytdx3y

24 November 2022

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