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P-glycoprotein: from genomics to mechanism.
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Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
review article
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Europe PubMed Central
title
P-glycoprotein: from genomics to mechanism
(English)
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stated in
Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
main subject
genomics
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author
Chava Kimchi-Sarfaty
series ordinal
2
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Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
Michael M. Gottesman
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4
object named as
Michael M Gottesman
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Europe PubMed Central
PubMed publication ID
14576852
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
author name string
Suresh V Ambudkar
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1
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Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
Zuben E Sauna
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3
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Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
language of work or name
English
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publication date
1 October 2003
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Europe PubMed Central
PubMed publication ID
14576852
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
published in
Oncogene
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stated in
Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
volume
22
1 reference
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Europe PubMed Central
PubMed publication ID
14576852
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
issue
47
1 reference
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Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
page(s)
7468-7485
1 reference
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Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
cites work
Relation Between the Turnover Number for Vinblastine Transport and for Vinblastine-stimulated ATP Hydrolysis by Human P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and preliminary analysis of a P-glycoprotein-specific [3H]-benzophenone photoaffinity label based on (-)-stipiamide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A reciprocal relationship between the genetic diversity at two metabolically-linked isozyme loci in several conifer species
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian ABC transporters in health and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The multidrug resistance protein family.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A family of drug transporters: the multidrug resistance-associated proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ABC transporters as phenotypic markers and functional regulators of stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of positional isotope exchange in ATP by cleavage of the beta P-O gamma P bond. Demonstration of negligible positional isotope exchange by myosin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new polymorphism (N21D) in the exon 2 of the human MDR1 gene encoding the P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the cyclosporin-binding site in P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of the Iodomycin Binding Site in Hamster P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A multidrug resistance transporter from human MCF-7 breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multidrug resistance and cancer: the role of the human ABC transporter ABCG2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacogenomics--drug disposition, drug targets, and side effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrinsic drug resistance in human kidney cancer is associated with expression of a human multidrug-resistance gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of a multidrug resistance gene in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overview: ABC transporters and human disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multidrug resistance in cancer: role of ATP-dependent transporters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic analysis of the multidrug transporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemistry of multidrug resistance mediated by the multidrug transporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein and multidrug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Both ATP sites of human P-glycoprotein are essential but not symmetric
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the ATP-binding subunit of an ABC transporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of functionally variant MDR1 alleles among European Americans and African Americans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bacterial multidrug resistance mediated by a homologue of the human multidrug transporter P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MRP3, an organic anion transporter able to transport anti-cancer drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GTP-stimulated phosphorylation of P-glycoprotein in transporting vesicles from KB-V1 multidrug resistant cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the Adenosine Triphosphatase Activity of the Periplasmic Histidine Permease, a Traffic ATPase (ABC Transporter)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biology of the multidrug resistance-associated protein, MRP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Covalent modification of human P-glycoprotein mutants containing a single cysteine in either nucleotide-binding fold abolishes drug-stimulated ATPase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Merck Frosst Award Lecture 1998. Molecular dissection of the human multidrug resistance P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cross-linking of human multidrug resistance P-glycoprotein by the substrate, tris-(2-maleimidoethyl)amine, is altered by ATP hydrolysis. Evidence for rotation of a transmembrane helix.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defining the drug-binding site in the human multidrug resistance P-glycoprotein using a methanethiosulfonate analog of verapamil, MTS-verapamil
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linking compounds as molecular rulers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Energy coupling to periplasmic binding protein-dependent transport systems: stoichiometry of ATP hydrolysis during transport in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
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7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylcholine translocase: a physiological role for the mdr2 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of P-glycoprotein ATPase activity by beryllium fluoride
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein. The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Importance of the conserved Walker B glutamate residues, 556 and 1201, for the completion of the catalytic cycle of ATP hydrolysis by human P-glycoprotein (ABCB1).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for the vectorial nature of drug (substrate)-stimulated ATP hydrolysis by human P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of action of multidrug-resistance-linked P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic polymorphisms of the human MDR1 drug transporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A general pattern for substrate recognition by P-glycoprotein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATP hydrolysis cycles and mechanism in P-glycoprotein and CFTR.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vanadate-induced trapping of nucleotides by purified maltose transport complex requires ATP hydrolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptibility to renal epithelial tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDR-1 C3435T genetic polymorphism and tobacco-related lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of the gene encoding the transmembrane transporter protein ABC-C6 cause pseudoxanthoma elasticum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the ATPase activity of purified Chinese hamster P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Investigation of the role of glutamine-471 and glutamine-1114 in the two catalytic sites of P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of conserved carboxylate residues in the nucleotide binding sites of P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Both P-glycoprotein Nucleotide-binding Sites Are Catalytically Active
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the domains of photoincorporation of the 3'- and 7-benzophenone analogues of taxol in the carboxyl-terminal half of murine mdr1b P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206948
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1206948
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
Dimensions Publication ID
1023336886
0 references
PubMed publication ID
14576852
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14576852
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
ResearchGate publication ID
231587828
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