(Q40814929)

English

Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis

scientific article published on 3 April 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

author name string

Sauna ZE

1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Smith MM

2

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Muller M

3

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Ambudkar SV

4

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

language of work or name

0 references

publication date

3 April 2001

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

number of pages

10

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

276

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

21199-21208

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Both ATP sites of human P-glycoprotein are essential but not symmetric

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein. The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

The catalytic cycle of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Functional expression of human P-glycoprotein from plasmids using vaccinia virus-bacteriophage T7 RNA polymerase system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

ATP binding properties of the nucleotide-binding folds of SUR1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Photochemical mapping of the active site of myosin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

ATP hydrolysis by multidrug-resistance protein from Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

ATP hydrolysis cycles and mechanism in P-glycoprotein and CFTR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Investigation of the role of glutamine-471 and glutamine-1114 in the two catalytic sites of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Transition-state formation in ATPase-negative mutants of human MDR1 protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Conserved walker A Ser residues in the catalytic sites of P-glycoprotein are critical for catalysis and involved primarily at the transition state step.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Large scale purification of detergent-soluble P-glycoprotein from Pichia pastoris cells and characterization of nucleotide binding properties of wild-type, Walker A, and Walker B mutant proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

The ATPase and ATP-binding functions of P-glycoprotein--modulation by interaction with defined phospholipids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Crystal structure of the ATP-binding subunit of an ABC transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Structure of the ArsA ATPase: the catalytic subunit of a heavy metal resistance pump

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Regulation by ATP and ADP of CFTR chloride channels that contain mutant nucleotide-binding domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Dual effects of ADP and adenylylimidodiphosphate on CFTR channel kinetics show binding to two different nucleotide binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Different Binding Properties and Affinities for ATP and ADP among Sulfonylurea Receptor Subtypes, SUR1, SUR2A, and SUR2B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Inhibition of P-glycoprotein ATPase activity by procedures involving trapping of nucleotide in catalytic sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Inhibition of P-glycoprotein ATPase activity by beryllium fluoride

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

A rapid, sensitive, and specific method for the determination of protein in dilute solution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Drug-stimulated nucleotide trapping in the human multidrug transporter MDR1. Cooperation of the nucleotide binding domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Both P-glycoprotein Nucleotide-binding Sites Are Catalytically Active

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Preparation and properties of 2'(or 3')-O-(2,4,6-trinitrophenyl) adenosine 5'-triphosphate, an analog of adenosine triphosphate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Fluorescence studies on the nucleotide binding domains of the P-glycoprotein multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100886200

21 January 2018

Identifiers

10.1074/JBC.M100886200

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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