(Q53911158)

English

Conserved walker A Ser residues in the catalytic sites of P-glycoprotein are critical for catalysis and involved primarily at the transition state step.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

Conserved walker A Ser residues in the catalytic sites of P-glycoprotein are critical for catalysis and involved primarily at the transition state step. (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

author name string

Urbatsch IL

1

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

Gimi K

2

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

Wilke-Mounts S

3

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

Senior AE

4

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

language of work or name

0 references

publication date

1 August 2000

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

275

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

32

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

25031-25038

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

The P-glycoprotein efflux pump: how does it transport drugs?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Membrane topology of a cysteine-less mutant of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Transmembrane organization of mouse P-glycoprotein determined by epitope insertion and immunofluorescence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Modulation of ATP and drug binding by monoclonal antibodies against P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Identification of the cyclosporin-binding site in P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Characterization of the ATPase activity of purified Chinese hamster P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

The catalytic cycle of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Effects of lipids on ATPase activity of purified Chinese hamster P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Large scale purification of detergent-soluble P-glycoprotein from Pichia pastoris cells and characterization of nucleotide binding properties of wild-type, Walker A, and Walker B mutant proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Crystal structure of the ATP-binding subunit of an ABC transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Purification and characterization of HisP, the ATP-binding subunit of a traffic ATPase (ABC transporter), the histidine permease of Salmonella typhimurium. Solubility, dimerization, and ATPase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Photoaffinity labelling of P-glycoprotein catalytic sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

ATP hydrolysis by multidrug-resistance protein from Chinese hamster ovary cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Both ATP sites of human P-glycoprotein are essential but not symmetric

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Mechanism of the ArsA ATPase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Identification of Residues in the Drug-binding Domain of Human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003962200

21 January 2018

Identifiers

10.1074/JBC.M003962200

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/10831598

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q53911158&oldid=1769542756"