(Q28478966)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Rapid evaluation in whole blood culture of regimens for XDR-TB containing PNU-100480 (sutezolid), TMC207, PA-824, SQ109, and pyrazinamide (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

ChEBI release 2020-05-28

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Mark Mitton-Fry

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

Robert S Wallis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Lynn Ladutko

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Sheldon Campbell

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Darcy Paige

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Annette Silvia

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Paul F Miller

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

18 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

e30479

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

21 January 2020

copyright license

start time

18 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Sterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

The mechanism of action of PA-824: Novel insights from transcriptional profiling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjects

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

The diarylquinoline TMC207 for multidrug-resistant tuberculosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Lack of activity of orally administered clofazimine against intracellular Mycobacterium tuberculosis in whole-blood culture

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Sterilizing activity of novel TMC207- and PA-824-containing regimens in a murine model of tuberculosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Mycobacterium tuberculosis acg gene is required for growth and virulence in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Biomarker-assisted dose selection for safety and efficacy in early development of PNU-100480 for tuberculosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

PA-824 exhibits time-dependent activity in a murine model of tuberculosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Bactericidal activity of the diarylquinoline TMC207 against Mycobacterium tuberculosis outside and within cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Bactericidal potencies of new regimens are not predictive of their sterilizing potencies in a murine model of tuberculosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

In vitro interactions between new antitubercular drug candidates SQ109 and TMC207.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

The antituberculosis drug pyrazinamide affects the course of cutaneous leishmaniasis in vivo and increases activation of macrophages and dendritic cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Promising antituberculosis activity of the oxazolidinone PNU-100480 relative to that of linezolid in a murine model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

A single dose of vitamin D enhances immunity to mycobacteria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Interspecies pharmacokinetics and in vitro metabolism of SQ109.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Novel approach to characterization of combined pharmacodynamic effects of antimicrobial agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Bactericidal activity in whole blood as a potential surrogate marker of immunity after vaccination against tuberculosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Drug tolerance in Mycobacterium tuberculosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Rapid differentiation of bovine and human tubercle bacilli based on a characteristic mutation in the bovine pyrazinamidase gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Phenotypic tolerance: the search for beta-lactam antibiotics that kill nongrowing bacteria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

Survival and replication of clinical Mycobacterium tuberculosis isolates in the context of human innate immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261206

A whole blood bactericidal assay for tuberculosis

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030479

Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030479

Addition of PNU-100480 to first-line drugs shortens the time needed to cure murine tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030479

Whole Blood Bactericidal Activity during Treatment of Pulmonary Tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030479

Significance of in-vitro penicillin tolerance in experimental enterococcal endocarditis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22279595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0030479

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

ADS bibcode

2012PLoSO...730479W

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

22279595

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22279595%20AND%20SRC:MED&resulttype=core&format=json