(Q28481438)

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Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412376%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity (English)

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Europe PubMed Central

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25 January 2020

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25 January 2020

Massimiliano Pagani

8

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25 January 2020

Sergio Abrignani

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25 January 2020

Raffaele De Francesco

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25 January 2020

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Annalisa Bianco

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25 January 2020

Veronica Reghellin

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25 January 2020

Lorena Donnici

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25 January 2020

Simone Fenu

4

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25 January 2020

Reinaldo Alvarez

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25 January 2020

Chiara Baruffa

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25 January 2020

Petra Neddermann

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25 January 2020

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8 March 2012

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25 January 2020

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25 January 2020

8

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25 January 2020

3

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25 January 2020

e1002576

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25 January 2020

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8 March 2012

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Hepatitis C virus NS5A protein interacts with phosphatidylinositol 4-kinase type IIIalpha and regulates viral propagation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

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Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites

1 reference

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Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

1 reference

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Viral reorganization of the secretory pathway generates distinct organelles for RNA replication

1 reference

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SCY-635, a Novel Nonimmunosuppressive Analog of Cyclosporine That Exhibits Potent Inhibition of Hepatitis C Virus RNA Replication In Vitro

1 reference

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19 March 2017

Identification of Hepatitis C Virus NS5A Inhibitors

1 reference

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19 March 2017

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

1 reference

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19 March 2017

Naturally Occurring Hepatitis C Virus Subgenomic Deletion Mutants Replicate Efficiently in Huh-7 Cells and Are trans-Packaged In Vitro To Generate Infectious Defective Particles

1 reference

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19 March 2017

Role of Oxysterol Binding Protein in Hepatitis C Virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication

1 reference

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19 March 2017

A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus

1 reference

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19 March 2017

Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Identification of Residues Required for RNA Replication in Domains II and III of the Hepatitis C Virus NS5A Protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Distinct Golgi populations of phosphatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Efficient initiation of HCV RNA replication in cell culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Subcellular locations of phosphatidylinositol 4-kinase isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

19 March 2017

Hepatitis C virus stimulates the phosphatidylinositol 4-kinase III alpha-dependent phosphatidylinositol 4-phosphate production that is essential for its replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297592

29 September 2017

Discovery of potent hepatitis C virus NS5A inhibitors with dimeric structures.

1 reference

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29 September 2017

Multifaceted roles for lipids in viral infection

1 reference

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29 September 2017

Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity.

1 reference

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29 September 2017

New HCV therapies on the horizon

1 reference

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Development of novel therapies for hepatitis C.

1 reference

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Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

1 reference

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Role of annexin A2 in the production of infectious hepatitis C virus particles

1 reference

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Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2).

1 reference

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Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication

1 reference

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NS5A--from obscurity to new target for HCV therapy

1 reference

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1 reference

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Modification of intracellular membrane structures for virus replication

1 reference

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Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalpha

1 reference

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Mechanisms of drug inhibition of signalling molecules

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1 reference

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29 September 2017

A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1.

1 reference

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Viral RNA replication in association with cellular membranes.

1 reference

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29 September 2017

The NS5A protein of hepatitis C virus is a zinc metalloprotein

1 reference

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Molecular model of the specificity pocket of the hepatitis C virus protease: implications for substrate recognition.

1 reference

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29 September 2017

Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002576

21 January 2018

Domain 3 of non-structural protein 5A from hepatitis C virus is natively unfolded

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002576

21 January 2018

Domain 2 of nonstructural protein 5A (NS5A) of hepatitis C virus is natively unfolded.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002576

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Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: in vitro and in vivo correlations.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002576

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002576

21 January 2018

Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and Golgi

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002576

21 January 2018

Identifiers

10.1371/JOURNAL.PPAT.1002576

2 references

Consolidated OpenCitations Corpus – April 2017

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25 January 2020

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Consolidated OpenCitations Corpus – April 2017

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2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412376%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412376%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

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