(Q28483893)

English

Valproic acid downregulates RBP4 and elicits hypervitaminosis A-teratogenesis--a kinetic analysis on retinol/retinoic acid homeostatic system

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scholarly article

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Valproic acid downregulates RBP4 and elicits hypervitaminosis A-teratogenesis--a kinetic analysis on retinol/retinoic acid homeostatic system (English)

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author name string

Chao-Ming Chuang

1

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Chi-Huang Chang

2

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Hui-Er Wang

3

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Kuan-Chou Chen

4

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Chiung-Chi Peng

5

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Chiu-Lan Hsieh

6

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Robert Y Peng

7

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language of work or name

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publication date

2012

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7

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9

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e43692

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copyright license

Creative Commons Attribution 4.0 International

19 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Teratogenic mechanisms of medical drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

19 March 2017

Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

19 March 2017

Science review: carnitine in the treatment of valproic acid-induced toxicity - what is the evidence?

1 reference

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19 March 2017

The Ile-84-->Ser amino acid substitution in transthyretin interferes with the interaction with plasma retinol-binding protein

1 reference

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19 March 2017

Characterization of two post-translationally processed forms of human serum retinol-binding protein: altered ratios in chronic renal failure

1 reference

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19 March 2017

The risk of spina bifida aperta after first-trimester exposure to valproate in a prenatal cohort

1 reference

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19 March 2017

Interaction between Prealbumin and Retinol-Binding Protein Studied by Affinity Chromatography, Gel Filtration and Two-Phase Partition

1 reference

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19 March 2017

Retinyl ester formation by lecithin: retinol acyltransferase is a key regulator of retinoid homeostasis in mouse embryogenesis

1 reference

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19 March 2017

The role of extrahepatic retinol binding protein in the mobilization of retinoid stores

1 reference

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19 March 2017

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

1 reference

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7 April 2017

Effects of retinol binding protein-4 on vascular endothelial cells

1 reference

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29 September 2017

Coordinated gene expression during gilthead sea bream skeletogenesis and its disruption by nutritional hypervitaminosis A

1 reference

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29 September 2017

High dietary intake of retinol leads to bone marrow hypoxia and diaphyseal endosteal mineralization in rats

1 reference

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29 September 2017

Histone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases

1 reference

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29 September 2017

Some current insights into oxidative stress

1 reference

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29 September 2017

Valproic acid in pregnancy: how much are we endangering the embryo and fetus?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Inhibition of histone deacetylase as a new mechanism of teratogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Retinoids in embryonal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Mechanisms of action of valproate: a commentatory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Superoxide radical and iron modulate aconitase activity in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Retinoic acid embryopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Inactivation of beef brain alpha-ketoglutarate dehydrogenase complex by valproic acid and valproic acid metabolites. Possible mechanism of anticonvulsant and toxic actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Di-n-propylacetate and GABA degradation. Preferential inhibition of succinic semialdehyde dehydrogenase and indirect inhibition of GABA-transaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

29 September 2017

Multiple point action mechanism of valproic acid-teratogenicity alleviated by folic acid, vitamin C, and N-acetylcysteine in chicken embryo model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

2 June 2018

Positional apoptosis during vertebrate CNS development in the absence of endogenous retinoids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

2 June 2018

Phenytoin-induced teratogenesis: a molecular basis for the observed developmental delay during neurulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

2 June 2018

Distribution of valproic acid and its metabolites in various brain areas of dogs and rats after acute and prolonged treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

2 June 2018

Characterization of valproic acid-initiated homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

27 November 2018

Expression and characterization of recombinant human retinol-binding protein in Pichia pastoris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

27 November 2018

An in ovo chicken model to study the systemic and localized teratogenic effects of valproic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446952

27 November 2018

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

1 reference

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27 November 2018

Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis

1 reference

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27 November 2018

Retinoid signaling required for normal heart development regulates GATA-4 in a pathway distinct from cardiomyocyte differentiation.

1 reference

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27 November 2018

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1 reference

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27 November 2018

Retinoic acid receptors and cellular retinoid binding proteins. III. Their differential transcript distribution during mouse nervous system development.

1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

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inferred from PubMed ID database lookup

Malformations induced in cultured rat embryos by enzymically generated active oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of specific retinoid-binding sites and expression of cellular retinoic-acid-binding protein (CRABP) in the early mouse embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of retinaldehyde bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of plasma hydroperoxide concentrations by the ferrous oxidation-xylenol orange assay in conjunction with triphenylphosphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

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based on heuristic

inferred from PubMed ID database lookup

Distinct roles for cellular retinoic acid-binding proteins I and II in regulating signaling by retinoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valproic acid overdose and L-carnitine therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excessive intake of vitamin A as a cause of congenital anomalies in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rate of metabolism of retinol and retinoic acid-maintained rats after a single dose of radioactive retinol

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23028466

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0043692

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2012PLoSO...743692C

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