(Q28484490)

2

Kavitha

Akula

1 reference

29 October 2023

Alla Arzumanyan

3

Alla

Arzumanyan

1 reference

29 October 2023

Jennifer Alleva

4

Jennifer

Alleva

1 reference

29 October 2023

Marcus Jackson

5

Marcus

Jackson

1 reference

29 October 2023

Eugeney Bichenkov

6

Eugeney

Bichenkov

1 reference

29 October 2023

Joel B Sheffield

7

Joel B

Sheffield

1 reference

29 October 2023

Mark A Feitelson

8

Mark A

Feitelson

1 reference

29 October 2023

Christian E Schafmeister

9

Christian E

Creative Commons Attribution 4.0 International

Schafmeister

1 reference

29 October 2023

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS One

0 references

volume

7

0 references

page(s)

e45948

0 references

issue

10

0 references

copyright license

start time

18 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

The genetics of the p53 pathway, apoptosis and cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Disrupting protein-protein interactions with non-peptidic, small molecule alpha-helix mimetics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Synthetic mimetics of protein secondary structure domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

In Silico Improvement of beta3-peptide inhibitors of p53 x hDM2 and p53 x hDMX

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Beta-peptides with improved affinity for hDM2 and hDMX.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Unlocking the Mdm2-p53 loop: ubiquitin is the key.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Targeting protein-protein interactions: lessons from p53/MDM2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Synthetic non-peptide mimetics of alpha-helices

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Structural basis for understanding oncogenic p53 mutations and designing rescue drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

beta-Peptides as inhibitors of protein-protein interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Molecular properties that influence the oral bioavailability of drug candidates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Regulation of P53 stability in p53 mutated human and mouse hepatoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Synthesis of hexa- and pentasubstituted diketopiperazines from sterically hindered amino acids

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Exploiting an inherent neighboring group effect of alpha-amino acids to synthesize extremely hindered dipeptides

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Shape-programmable macromolecules.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

A hydrogen bond surrogate approach for stabilization of short peptide sequences in alpha-helical conformation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Terphenyl-based helical mimetics that disrupt the p53/HDM2 interaction

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475717

Solid-phase synthesis of functionalized bis-peptides

27 November 2018

1 reference

12 December 2020

Residue-based control of helix shape in β-peptide oligomers

1 reference

12 December 2020

Probing the structural requirements of peptoids that inhibit HDM2-p53 interactions

1 reference

12 December 2020

Determinants of specificity of MDM2 for the activation domains of p53 and p65: proline27 disrupts the MDM2-binding motif of p53

1 reference

12 December 2020

Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide

1 reference

12 December 2020

Atomic structure of a short alpha-helix stabilized by a main chain hydrogen-bond surrogate

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0045948

Identifiers

DOI

1 reference

3988903

ADS bibcode

2012PLoSO...745948B

0 references

3988903

1 reference

1 reference

1 reference