(Q28486184)

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Fingolimod phosphate attenuates oligomeric amyloid β-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23593505%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Fingolimod phosphate attenuates oligomeric amyloid β-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23593505%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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based on heuristic

inferred from title

FTY720-phosphate

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ChEBI release 2020-05-28

toxic encephalopathy

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based on heuristic

inferred from title

Hiroshi Horiuchi

3

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28 February 2020

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Yukiko Doi

1

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28 February 2020

Hideyuki Takeuchi

2

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28 February 2020

Taketo Hanyu

4

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28 February 2020

Jun Kawanokuchi

5

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28 February 2020

Shijie Jin

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28 February 2020

Bijay Parajuli

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28 February 2020

Yoshifumi Sonobe

8

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28 February 2020

Tetsuya Mizuno

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28 February 2020

Akio Suzumura

10

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28 February 2020

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12 April 2013

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28 February 2020

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Europe PubMed Central

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28 February 2020

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28 February 2020

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28 February 2020

e61988

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28 February 2020

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Creative Commons Attribution 4.0 International

12 April 2013

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April 2022 Public Data File from Crossref

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0 references

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

19 March 2017

The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

19 March 2017

Involvement of BDNF receptor TrkB in spatial memory formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

19 March 2017

Neurotrophins: roles in neuronal development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

19 March 2017

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

19 March 2017

Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

7 April 2017

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

7 April 2017

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

7 April 2017

Fingolimod phosphate promotes the neuroprotective effects of microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Alzheimer's disease and the amyloid β-protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Fingolimod for multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Interleukin-34 selectively enhances the neuroprotective effects of microglia to attenuate oligomeric amyloid-β neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

TrkB signalling pathways in LTP and learning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Microglia activated with the toll-like receptor 9 ligand CpG attenuate oligomeric amyloid {beta} neurotoxicity in in vitro and in vivo models of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

29 September 2017

Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

2 June 2018

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

2 June 2018

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

Phosphorylated FTY720 stimulates ERK phosphorylation in astrocytes via S1P receptors.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB-PLCgamma pathway, reduced anxiety, and facilitated learning

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061988

21 January 2018

Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

27 November 2018

Ultrastructural localization of full-length trkB immunoreactivity in rat hippocampus suggests multiple roles in modulating activity-dependent synaptic plasticity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

27 November 2018

Immunocytochemical localization of TrkB in the central nervous system of the adult rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

27 November 2018

Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625222

27 November 2018

Identifiers

10.1371/JOURNAL.PONE.0061988

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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28 February 2020

2013PLoSO...861988D

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23593505%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23593505%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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