(Q46733868)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

1 reference

Atul Deshpande

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Erene Mina

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Charles Glabe

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Jorge Busciglio

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

1 May 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

6011-6018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

Fetal human cortical neurons grown in culture: morphological differentiation, biochemical correlates and development of electrical activity.

28 January 2020

cites work

1 reference

12 December 2020

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

12 December 2020

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1 reference

12 December 2020

Serial killers: ordering caspase activation events in apoptosis

1 reference

12 December 2020

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

1 reference

12 December 2020

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

12 December 2020

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

1 reference

12 December 2020

Mitochondria and Ca(2+)in cell physiology and pathophysiology

1 reference

12 December 2020

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

1 reference

12 December 2020

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

1 reference

12 December 2020

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

12 December 2020

Synaptically released zinc: physiological functions and pathological effects.

1 reference

12 December 2020

Apoptosis: a link between cancer genetics and chemotherapy

1 reference

12 December 2020

Protection of cardiac mitochondria by diazoxide and protein kinase C: implications for ischemic preconditioning

1 reference

12 December 2020

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

1 reference

12 December 2020

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

1 reference

12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

12 December 2020

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

12 December 2020

The channel hypothesis of Alzheimer's disease: current status

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

New Class of Inhibitors of Amyloid-beta Fibril Formation. IMPLICATIONS FOR THE MECHANISM OF PATHOGENESIS IN ALZHEIMER'S DISEASE

1 reference

12 December 2020

Abeta toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets

1 reference

12 December 2020

Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition

1 reference

12 December 2020

Characterization of neuronal dystrophy induced by fibrillar amyloid beta: implications for Alzheimer's disease.

1 reference

12 December 2020

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

1 reference

12 December 2020

Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

1 reference

12 December 2020

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

1 reference

12 December 2020

Aberrant activation of focal adhesion proteins mediates fibrillar amyloid beta-induced neuronal dystrophy.

1 reference

12 December 2020

Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

1 reference

12 December 2020

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

1 reference

12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

12 December 2020

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

1 reference

12 December 2020

GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons.

1 reference

12 December 2020

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

12 December 2020

beta-Amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer pathology

1 reference

12 December 2020

Self-assembly of Abeta(1-42) into globular neurotoxins.

1 reference

12 December 2020

Methodological variables in the assessment of beta amyloid neurotoxicity

1 reference

12 December 2020

beta-Amyloid precursor protein and Alzheimer's disease: the peptide plot thickens

1 reference

12 December 2020

Cell death: critical control points

1 reference

12 December 2020

Calcium as sculptor and destroyer of neural circuitry

1 reference

12 December 2020

Intraneuronal amyloid-beta1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death

1 reference

12 December 2020

Architecture of the Alzheimer's A beta P ion channel pore

1 reference

12 December 2020

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

1 reference

12 December 2020

Cortical synaptic integration in vivo is disrupted by amyloid-beta plaques.

1 reference

12 December 2020

Mitochondrial mechanisms of neural cell apoptosis

1 reference

12 December 2020

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

1 reference

12 December 2020

Conformation-dependent antibodies target diseases of protein misfolding

1 reference

12 December 2020

Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

1 reference

12 December 2020

Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence

1 reference

12 December 2020

Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides

1 reference

12 December 2020

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

12 December 2020

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

1 reference

12 December 2020

Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease

1 reference

12 December 2020

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

1 reference

12 December 2020

ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons.

1 reference

12 December 2020

Brain, aging and neurodegeneration: role of zinc ion availability

1 reference

12 December 2020

Amyloid ion channels: a common structural link for protein-misfolding disease

1 reference

12 December 2020

Aggregation and porin-like channel activity of a beta sheet peptide

1 reference

12 December 2020

The synaptic Abeta hypothesis of Alzheimer disease

1 reference

12 December 2020

Ca2+ dysregulation induces mitochondrial depolarization and apoptosis: role of Na+/Ca2+ exchanger and AKT.

1 reference

12 December 2020

Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

1 reference

12 December 2020

Caspase family proteases and apoptosis

1 reference

12 December 2020

Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology

1 reference

12 December 2020

Zinc and copper: pharmacological probes and endogenous modulators of neuronal excitability.

1 reference

12 December 2020

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

12 December 2020

Patterns of cell death.

1 reference

12 December 2020

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

1 reference

12 December 2020

Modulation of A beta adhesiveness and secretase site cleavage by zinc.

1 reference

12 December 2020

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

1 reference

12 December 2020

Beta-amyloid induces apoptosis in human-derived neurotypic SH-SY5Y cells

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

1 reference

12 December 2020

Mitochondrial control of apoptosis: the role of cytochrome c

1 reference

12 December 2020

Calcium - a life and death signal

1 reference

12 December 2020

10.1523/JNEUROSCI.1189-06.2006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16738244%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference