(Q44281893)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

title

Aberrant activation of focal adhesion proteins mediates fibrillar amyloid beta-induced neuronal dystrophy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

author name string

Elizabeth A Grace

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Jorge Busciglio

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

language of work or name

English

0 references

publication date

1 January 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

volume

23

1 reference

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16 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

page(s)

493-502

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

16 December 2019

cites work

1 reference

12 December 2020

Prostatic carcinoma cell migration via alpha(v)beta3 integrin is modulated by a focal adhesion kinase pathway

1 reference

12 December 2020

Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST

1 reference

12 December 2020

"Apoptotic" biochemical cascades in synaptic compartments: roles in adaptive plasticity and neurodegenerative disorders

1 reference

12 December 2020

The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin

1 reference

12 December 2020

Neuroplasticity failure in Alzheimer's disease: bridging the gap between plaques and tangles

1 reference

12 December 2020

The noncatalytic domain of protein-tyrosine phosphatase-PEST targets paxillin for dephosphorylation in vivo

1 reference

12 December 2020

Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

1 reference

12 December 2020

Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells.

1 reference

12 December 2020

Tyrosine phosphorylation of paxillin alpha is involved in temporospatial regulation of paxillin-containing focal adhesion formation and F-actin organization in motile cells

1 reference

12 December 2020

Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth

1 reference

12 December 2020

Integrin alpha(1) beta(1)-mediated activation of cyclin-dependent kinase 5 activity is involved in neurite outgrowth and human neurofilament protein H Lys-Ser-Pro tail domain phosphorylation.

1 reference

12 December 2020

Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration

1 reference

12 December 2020

Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants

1 reference

12 December 2020

A FE65 polymorphism associated with risk of developing sporadic late-onset alzheimer's disease but not with Abeta loading in brains

1 reference

12 December 2020

Paxillin interactions

1 reference

12 December 2020

Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation.

1 reference

12 December 2020

Alzheimer's disease: genes, proteins, and therapy

1 reference

12 December 2020

FE65 in Alzheimer's disease: neuronal distribution and association with neurofibrillary tangles

1 reference

12 December 2020

The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

1 reference

12 December 2020

Taking cell-matrix adhesions to the third dimension

1 reference

12 December 2020

Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

1 reference

12 December 2020

A candidate molecular mechanism for the association of an intronic polymorphism of FE65 with resistance to very late onset dementia of the Alzheimer type

1 reference

12 December 2020

Neurodegenerative disease: amyloid pores from pathogenic mutations

1 reference

12 December 2020

Characterization of neuronal dystrophy induced by fibrillar amyloid beta: implications for Alzheimer's disease

1 reference

12 December 2020

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

12 December 2020

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

12 December 2020

Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau

1 reference

12 December 2020

beta-Amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer pathology

1 reference

12 December 2020

Methodological variables in the assessment of beta amyloid neurotoxicity

1 reference

12 December 2020

Expression of intercellular adhesion molecule 1 (ICAM-1) in Alzheimer's disease

1 reference

12 December 2020

Immunohistochemical localization of vitronectin, its receptor and beta-3 integrin in Alzheimer brain tissue

1 reference

12 December 2020

1 reference

12 December 2020

Patterns of aberrant sprouting in Alzheimer's disease

1 reference

12 December 2020

Neuritic pathology and dementia in Alzheimer's disease

1 reference

12 December 2020

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

12 December 2020

Dynamic cytoskeleton-integrin associations induced by cell binding to immobilized fibronectin

1 reference

12 December 2020

Senile plaques as aberrant sprout-stimulating structures

1 reference

12 December 2020

Cellular and substrate adhesion molecules (integrins) and their ligands in cerebral amyloid plaques in Alzheimer's disease.

1 reference

12 December 2020

Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: identification of a vinculin and pp125Fak-binding region

1 reference

12 December 2020

Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL

1 reference

12 December 2020

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

1 reference

12 December 2020

Focal adhesion proteins associated with apical stress fibers of human fibroblasts

1 reference

12 December 2020

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

1 reference

12 December 2020

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

1 reference

12 December 2020

Interaction of beta-amyloid peptides with integrins in a human nerve cell line

1 reference

12 December 2020

beta-Amyloid protein induces platelet aggregation and supports platelet adhesion.

1 reference

12 December 2020

Focal adhesion kinase and associated proteins

1 reference

12 December 2020

Focal adhesion kinase expressed by nerve cell lines shows increased tyrosine phosphorylation in response to Alzheimer's A beta peptide

1 reference

12 December 2020

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

12 December 2020

Appearance of localized immunoreactivity for the alpha 4 integrin subunit and for fibronectin in brains from Alzheimer's, Lewy body dementia patients and aged controls

1 reference

12 December 2020

Alzheimer's disease-like dystrophic neurites characteristically associated with senile plaques are not found within other neurodegenerative diseases unless amyloid beta-protein deposition is present

1 reference

12 December 2020

Hyperactivation of signal transduction systems in Alzheimer's disease

1 reference

12 December 2020

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

1 reference

12 December 2020

Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

1 reference

12 December 2020

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

1 reference

12 December 2020

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

1 reference

12 December 2020

Mechanisms of neuronal degeneration in Alzheimer's disease

1 reference

12 December 2020

A beta peptide enhances focal adhesion kinase/Fyn association in a rat CNS nerve cell line

1 reference

12 December 2020

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II.

1 reference

12 December 2020

Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components

1 reference

12 December 2020

Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding

1 reference

12 December 2020

Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells

1 reference

12 December 2020

Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5.

1 reference

12 December 2020

Neuronal localization of presenilin-1 and association with amyloid plaques and neurofibrillary tangles in Alzheimer's disease.

1 reference

12 December 2020

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

1 reference

12 December 2020

Integrin Mac-1 and beta-amyloid in microglial release of nitric oxide

1 reference

12 December 2020

Structure and function of LIM domains

1 reference

12 December 2020

Rapid impact of beta-amyloid on paxillin in a neural cell line

1 reference

12 December 2020

Cell adhesion to laminin 1 or 5 induces isoform-specific clustering of integrins and other focal adhesion components.

1 reference

12 December 2020

The role of the amyloid protein precursor (APP) in Alzheimer's disease: does the normal function of APP explain the topography of neurodegeneration?

1 reference

12 December 2020

LIM domains: multiple roles as adapters and functional modifiers in protein interactions

1 reference

12 December 2020

Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins

1 reference

12 December 2020

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

1 reference

12 December 2020

Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration

1 reference

12 December 2020

Cell adhesion molecules in neural plasticity and pathology: similar mechanisms, distinct organizations?

1 reference

12 December 2020

The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type

1 reference

12 December 2020

10.1523/JNEUROSCI.23-02-00493.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12533609%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PubMed publication ID

12533609

1 reference