(Q53234381)

12 May 2018

title

Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease. (English)

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12 May 2018

author

Paolo Paganetti

4

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12 May 2018

author name string

Lorenzo A

1

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12 May 2018

Yuan M

2

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12 May 2018

Zhang Z

3

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12 May 2018

Sturchler-Pierrat C

5

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12 May 2018

Staufenbiel M

6

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12 May 2018

Mautino J

7

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12 May 2018

Vigo FS

8

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12 May 2018

Sommer B

9

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12 May 2018

Yankner BA

10

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12 May 2018

language of work or name

English

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publication date

1 May 2000

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12 May 2018

published in

Nature Neuroscience

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12 May 2018

volume

3

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12 May 2018

page(s)

460-464

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12 May 2018

issue

5

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12 May 2018

https://scigraph.springernature.com/pub.10.1038/74833

exact match

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cites work

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In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

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Methodological variables in the assessment of beta amyloid neurotoxicity

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7 January 2021

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7 January 2021

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

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Hydrogen peroxide mediates amyloid beta protein toxicity

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7 January 2021

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beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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7 January 2021

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An antibody to beta amyloid and the amyloid precursor protein inhibits cell-substratum adhesion in many mammalian cell types

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beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin

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7 January 2021

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Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

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7 January 2021

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7 January 2021

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7 January 2021

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

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The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures

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7 January 2021

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7 January 2021

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Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis

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The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity

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Mice devoid of PrP are resistant to scrapie

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Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells

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Intracellular accumulation of insoluble, newly synthesized abetan-42 in amyloid precursor protein-transfected cells that have been treated with Abeta1-42.

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7 January 2021

Amyloid precursor protein truncated at any of the gamma-secretase sites is not cleaved to beta-amyloid

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Establishment of a germ-line competent C57BL/6 embryonic stem cell line

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7 January 2021

Partial purification and characterization of the (Ca2+ + Mg2+)-ATPase from squid optic nerve plasma membrane

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7 January 2021

Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester.

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7 January 2021

Identifiers

DOI

10.1038/74833

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12 May 2018

PubMed ID

10769385

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12 May 2018