(Q73107254)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10531420%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures (English)

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1 November 2019

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1

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1 November 2019

author name string

G Multhaup

2

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1 November 2019

F Maher

3

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1 November 2019

S Bellingham

4

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1 November 2019

J Camakaris

5

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1 November 2019

H Zheng

6

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1 November 2019

A I Bush

7

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1 November 2019

K Beyreuther

8

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1 November 2019

C L Masters

9

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1 November 2019

R Cappai

10

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1 November 2019

publication date

1 November 1999

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1 November 2019

published in

Journal of Neuroscience

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1 November 2019

volume

19

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1 November 2019

issue

21

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1 November 2019

page(s)

9170-9179

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Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 November 2019

cites work

1 reference

12 December 2020

Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).

1 reference

12 December 2020

Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity.

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12 December 2020

Genetic and molecular basis for copper toxicity

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12 December 2020

Neurotoxicity of a prion protein fragment

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12 December 2020

The amyloid β protein precursor or proteinase nexin II from mouse is closer related to its human homolog than previously reported

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12 December 2020

Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis

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12 December 2020

Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis

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12 December 2020

Prion protein fragment interacts with PrP-deficient cells

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12 December 2020

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

12 December 2020

Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro

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12 December 2020

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

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12 December 2020

Transgenic mice expressing Alzheimer amyloid precursor proteins

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12 December 2020

Superoxide-dependent peroxidase activity of H48Q: a superoxide dismutase variant associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

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12 December 2020

Effects of copper on survival of prion protein knockout neurons and glia.

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12 December 2020

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

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12 December 2020

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

1 reference

12 December 2020

Promotion of transition metal-induced reactive oxygen species formation by beta-amyloid

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12 December 2020

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

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12 December 2020

The role of glutathione in copper metabolism and toxicity.

1 reference

12 December 2020

Copper, iron and zinc in Alzheimer's disease senile plaques

1 reference

12 December 2020

Intraneuronal aluminum potentiates iron-induced oxidative stress in cultured rat hippocampal neurons.

1 reference

12 December 2020

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

12 December 2020

Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders

1 reference

12 December 2020

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

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12 December 2020

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

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12 December 2020

Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I.

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12 December 2020

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.

1 reference

12 December 2020

A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.

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12 December 2020

Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress.

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12 December 2020

Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide

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12 December 2020

Interaction between the zinc (II) and the heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP).

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12 December 2020

Nerve endings from rat brain tissue release copper upon depolarization. A possible role in regulating neuronal excitability

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12 December 2020

Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer.

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12 December 2020

Copper binding to the prion protein: structural implications of four identical cooperative binding sites

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12 December 2020

Identification of the prooxidant site of human ceruloplasmin: a model for oxidative damage by copper bound to protein surfaces

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12 December 2020

The cellular prion protein binds copper in vivo

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12 December 2020

Strain-specific prion-protein conformation determined by metal ions

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12 December 2020

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

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12 December 2020

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

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12 December 2020

Functional analysis of copper homeostasis in cell culture models: a new perspective on internal copper transport

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12 December 2020

A novel zinc(II) binding site modulates the function of the beta A4 amyloid protein precursor of Alzheimer's disease

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12 December 2020

The beta A4 amyloid precursor protein binding to copper.

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12 December 2020

The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

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12 December 2020

Collection and normal levels of the amyloid precursor protein in plasma

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12 December 2020

Protection of flupirtine on beta-amyloid-induced apoptosis in neuronal cells in vitro: prevention of amyloid-induced glutathione depletion.

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12 December 2020

An integrative hypothesis concerning the pathogenesis and progression of Alzheimer's disease

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12 December 2020

Identification of S100b protein as copper-binding protein and its suppression of copper-induced cell damage.

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12 December 2020

Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid beta-protein precursor

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12 December 2020

Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress.

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12 December 2020

Expression of copper trafficking genes in the mouse brain

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12 December 2020

The functional significance of brain metallothioneins

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12 December 2020

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth

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12 December 2020

Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells.

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12 December 2020

Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

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12 December 2020

Hydroxyl radical formation from cuprous ion and hydrogen peroxide: a spin-trapping study

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12 December 2020

4-hydroxy-2-nonenal pyrrole adducts in human neurodegenerative disease.

1 reference

12 December 2020

The cellular prion protein binds copper in vivo

1 reference

12 December 2020

10.1523/JNEUROSCI.19-21-09170.1999

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10531420%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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1 November 2019

PubMed publication ID

10531420

1 reference