(Q48679489)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9185546%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9185546%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

5

M P Mattson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9185546%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

I Kruman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9185546%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

A J Bruce-Keller

2

1 reference

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3 November 2019

D Bredesen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9185546%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

G Waeg

4

1 reference

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3 November 2019

language of work or name

English

0 references

publication date

1 July 1997

1 reference

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3 November 2019

published in

Journal of Neuroscience

1 reference

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3 November 2019

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9185546%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

5089-5100

1 reference

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3 November 2019

issue

13

1 reference

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Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

3 November 2019

cites work

1 reference

12 December 2020

The protooncogene bcl-2 inhibits apoptosis in PC12 cells

1 reference

12 December 2020

Neuroprotective action of cycloheximide involves induction of bcl-2 and antioxidant pathways

1 reference

12 December 2020

Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons

1 reference

12 December 2020

NMDA-dependent superoxide production and neurotoxicity.

1 reference

12 December 2020

Prolonged pretreatment with alpha-lipoic acid protects cultured neurons against hypoxic, glutamate-, or iron-induced injury.

1 reference

12 December 2020

Immunohistochemical evidence for apoptosis in Alzheimer's disease.

1 reference

12 December 2020

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

1 reference

12 December 2020

Ca2+ ionophore-induced apoptosis on cultured embryonic rat cortical neurons.

1 reference

12 December 2020

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

1 reference

12 December 2020

Calcium-Mediated Mechanisms in Chemically Induced Cell Death

1 reference

12 December 2020

Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate

1 reference

12 December 2020

4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes.

1 reference

12 December 2020

Oxidative stress in neurodegenerative diseases

1 reference

12 December 2020

Basic FGF, NGF, and IGFs protect hippocampal and cortical neurons against iron-induced degeneration.

1 reference

12 December 2020

Michael addition-type 4-hydroxy-2-nonenal adducts in modified low-density lipoproteins: markers for atherosclerosis

1 reference

12 December 2020

Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway

1 reference

12 December 2020

Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2.

1 reference

12 December 2020

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1 reference

12 December 2020

The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by beta-amyloid peptides.

1 reference

12 December 2020

Excitotoxicity at both NMDA and non-NMDA glutamate receptors is antagonized by aurintricarboxylic acid: evidence for differing mechanisms of action

1 reference

12 December 2020

Mitochondrial control of nuclear apoptosis.

1 reference

12 December 2020

BCL-2 blocks glutamate toxicity in neural cell lines

1 reference

12 December 2020

Cytotoxic and genotoxic effects of five n-alkanals in primary cultures of rat and human hepatocytes.

1 reference

12 December 2020

Signalling mechanisms and oxidative stress in apoptosis

1 reference

12 December 2020

A decrease in intracellular glutathione concentration precedes the onset of apoptosis in murine thymocytes

1 reference

12 December 2020

Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.

1 reference

12 December 2020

The use of tetrazolium salts to determine sites of damage to the mitochondrial electron transport chain in intact cells following in vitro photodynamic therapy with Photofrin II

1 reference

12 December 2020

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

12 December 2020

Lipid peroxidation in rat brain cortical slices as measured by the thiobarbituric acid test

1 reference

12 December 2020

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1 reference

12 December 2020

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

1 reference

12 December 2020

Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury.

1 reference

12 December 2020

Involvement of Ca2+ in the formation of high molecular weight DNA fragments in thymocyte apoptosis.

1 reference

12 December 2020

Oxygen free radicals and brain dysfunction

1 reference

12 December 2020

A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherent cells in culture

1 reference

12 December 2020

Generation of reactive oxygen intermediates after treatment of blasts of acute myeloblastic leukemia with cytosine arabinoside: role of bcl-2.

1 reference

12 December 2020

1 reference

12 December 2020

Identification of metabolic pathways of the lipid peroxidation product 4-hydroxynonenal by mitochondria isolated from rat kidney cortex.

1 reference

12 December 2020

Mechanisms and genes of cellular suicide

1 reference

12 December 2020

Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspensions

1 reference

12 December 2020

Aurintricarboxylic acid is an inhibitor of mu- and m-calpain

1 reference

12 December 2020

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

1 reference

12 December 2020

Cell death induced by beta-amyloid 1-40 in MES 23.5 hybrid clone: the role of nitric oxide and NMDA-gated channel activation leading to apoptosis

1 reference

12 December 2020

Differential induction of immediate early gene proteins in cultured neurons by beta-amyloid (A beta): association of c-Jun with A beta-induced apoptosis.

1 reference

12 December 2020

The impairment of mitochondrial membrane potential and mass in proliferating lymphocytes from vitamin E deficient animals is recovered by glutathione

1 reference

12 December 2020

Parkinson's disease. The apoptosis hypothesis.

1 reference

12 December 2020

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

12 December 2020

Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.

1 reference

12 December 2020

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

1 reference

12 December 2020

Role of cardiac glutathione transferase and of the glutathione S-conjugate export system in biotransformation of 4-hydroxynonenal in the heart

1 reference

12 December 2020

Monoclonal antibodies for detection of 4-hydroxynonenal modified proteins

1 reference

12 December 2020

Glutathione metabolism.

1 reference

12 December 2020

Apoptosis in the pathogenesis and treatment of disease

1 reference

12 December 2020

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1 reference

12 December 2020

Bcl-2 and the regulation of programmed cell death

1 reference

12 December 2020

Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function

1 reference

12 December 2020

Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons

1 reference

12 December 2020

Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose.

1 reference

12 December 2020

Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons

1 reference

12 December 2020

Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity

1 reference

12 December 2020

N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells

1 reference

12 December 2020

Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons.

1 reference

12 December 2020

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

12 December 2020

Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death

1 reference

12 December 2020

The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation

1 reference

12 December 2020

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

12 December 2020

Neuronal apoptosis: current understanding of molecular mechanisms and potential role in ischemic brain injury

1 reference

12 December 2020

Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reaction

1 reference

12 December 2020

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.

1 reference

12 December 2020

Cytotoxicity and metabolism of 4-hydroxy-2-nonenal and 2-nonenal in H2O2-resistant cell lines. Do aldehydic by-products of lipid peroxidation contribute to oxidative stress?

1 reference

12 December 2020

Metabolism of 4-hydroxynonenal, a cytotoxic lipid peroxidation product, in Ehrlich mouse ascites cells at different proliferation stages

1 reference

12 December 2020

Bcl-2 protects neural cells from cyanide/aglycemia-induced lipid oxidation, mitochondrial injury, and loss of viability

1 reference

12 December 2020

Role of oxidants in ischemic brain damage

1 reference

12 December 2020

A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide.

1 reference

12 December 2020

Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons

1 reference

12 December 2020

Free radicals in brain metabolism and pathology

1 reference

12 December 2020

3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice

1 reference

12 December 2020

Calcium, free radicals, and excitotoxic neuronal death in primary cell culture

1 reference

12 December 2020

Expression of bcl-2 inhibits cellular radical generation

1 reference

12 December 2020

Kinetic analysis of glutathione in anchored cells with monochlorobimane

1 reference

12 December 2020

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis.

1 reference

12 December 2020

10.1523/JNEUROSCI.17-13-05089.1997

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9185546%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9185546%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference