(Q43833707)

English

Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

scientific article published in January 2002

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scholarly article

1 reference

Europe PubMed Central

27 November 2017

Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Ritchie Williamson

1

1 reference

Europe PubMed Central

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12 May 2020

Timothy Scales

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

Bruce R Clark

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

Graham Gibb

4

1 reference

Europe PubMed Central

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12 May 2020

C Hugh Reynolds

5

1 reference

Europe PubMed Central

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12 May 2020

Stuart Kellie

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

Ian N Bird

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

Ian M Varndell

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

Paul W Sheppard

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

Ian Everall

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

Brian H Anderton

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 January 2002

1 reference

Europe PubMed Central

27 November 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

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12 May 2020

22

1 reference

Europe PubMed Central

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12 May 2020

10-20

1 reference

Europe PubMed Central

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12 May 2020

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta neurotoxicity not mediated by the mitogen-activated protein kinase cascade in cultured rat hippocampal and cortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible random coil-beta-sheet transition of the Alzheimer beta-amyloid fragment (25-35).

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo phosphorylation sites in fetal and adult rat tau

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal adhesion kinase expressed by nerve cell lines shows increased tyrosine phosphorylation in response to Alzheimer's A beta peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of (45)Ca(2+) influx and voltage-dependent Ca(2+) channel activity by beta-amyloid-(1-40) in rat cortical synaptosomes and cultured cortical neurons. Modulation by the proinflammatory cytokine interleukin-1beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal Adhesion Kinase in Rat Central Nervous System

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration mediated by glutamate and beta-amyloid peptide: a comparison and possible interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated amyloid beta protein(1-40) level induces CREB phosphorylation at serine-133 via p44/42 MAP kinase (Erk1/2)-dependent pathway in rat pheochromocytoma PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src family kinases are required for integrin but not PDGFR signal transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

β-Amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologic levels of beta-amyloid activate phosphatidylinositol 3-kinase with the involvement of tyrosine phosphorylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD98059 prevents neurite degeneration induced by fibrillar beta-amyloid in mature hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein tyrosine kinase, fyn, in Alzheimer's disease pathology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-2 mediates neuronal cell death induced by beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of phosphoinositide 3-kinase and the Cbl adaptor protein in coupling the alpha4beta1 integrin to mitogen-activated protein kinase signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid-induced activation of caspase-3 in primary cultures of rat neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's amyloid fibrils: structure and assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental changes in tau phosphorylation: fetal tau is transiently phosphorylated in a manner similar to paired helical filament-tau characteristic of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological levels of beta-amyloid increase tyrosine phosphorylation and cytosolic calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phosphatidylinositol 3-kinase by a complex of p59fyn and the receptor tyrosine kinase Xmrk is involved in malignant transformation of pigment cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofilament monoclonal antibodies RT97 and 8D8 recognize different modified epitopes in paired helical filament-tau in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and beta-amyloid in primary rat cortical neuronal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E, Dementia, and Cortical Deposition of β-Amyloid Protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dorothy Russell Memorial Lecture. The molecular pathology of Alzheimer's disease: are we any closer to understanding the neurodegenerative process?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitotoxicity hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological levels of beta-amyloid peptide stimulate protein kinase C in PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau interacts with src-family non-receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fetal-type phosphorylation of the tau in paired helical filaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of caspase-3 in beta-amyloid-induced apoptosis of cultured rat cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35).

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanosensitive tyrosine phosphorylation of paxillin and focal adhesion kinase in tracheal smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiology and pathology of tau protein kinases in relation to Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.22-01-00010.2002

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757621&resulttype=core&format=json

12 May 2020

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