(Q40561527)

English

Dorothy Russell Memorial Lecture. The molecular pathology of Alzheimer's disease: are we any closer to understanding the neurodegenerative process?

scientific article published on August 1994

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scholarly article

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Europe PubMed Central

21 September 2017

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Europe PubMed Central

Dorothy Russell Memorial Lecture. The molecular pathology of Alzheimer's disease: are we any closer to understanding the neurodegenerative process? (English)

1 reference

Europe PubMed Central

21 September 2017

Alzheimer's disease

0 references

neurodegeneration

1 reference

based on heuristic

inferred from title

author name string

Smith C

1

1 reference

Europe PubMed Central

21 September 2017

Anderton BH

2

1 reference

Europe PubMed Central

21 September 2017

publication date

1 August 1994

1 reference

Europe PubMed Central

21 September 2017

Neuropathology and Applied Neurobiology

1 reference

Europe PubMed Central

21 September 2017

20

1 reference

Europe PubMed Central

21 September 2017

4

1 reference

Europe PubMed Central

21 September 2017

322-338

1 reference

Europe PubMed Central

21 September 2017

Induction of amyloid precursor protein mRNA after heat shock in cultured human lymphoblastoid cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Tau protein kinase II is involved in the regulation of the normal phosphorylation state of tau protein.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Neuropathological staging of Alzheimer lesions and intellectual status in Alzheimer's and Parkinson's disease patients.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Neuropathological stageing of Alzheimer-related changes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Neurofilament monoclonal antibodies RT97 and 8D8 recognize different modified epitopes in paired helical filament-tau in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Developmental changes in tau phosphorylation: fetal tau is transiently phosphorylated in a manner similar to paired helical filament-tau characteristic of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Straight and paired helical filaments in Alzheimer disease have a common structural unit

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The amyloid beta-protein of Alzheimer's disease is chemotactic for mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Activation of protein kinase C increases the extracellular release of the transmembrane amyloid protein precursor of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Intraventricular infusions of antibodies to amyloid-beta-protein precursor impair the acquisition of a passive avoidance response in the rat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Spongiform alterations in brain biopsies of presenile dementia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Effects of injected Alzheimer beta-amyloid cores in rat brain.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Inhibition of beta-amyloid production by activation of protein kinase C.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Lack of Alzheimer pathology after beta-amyloid protein injections in rat brain.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

p42 map kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1Implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

beta-Amyloid protein amplifies calcium signalling in central neurons from the adult mouse.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Characterization of two distinct monoclonal antibodies to paired helical filaments: further evidence for fetal-type phosphorylation of the tau in paired helical filaments.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Involvement of amyloid precursor protein in memory formation in the rat: an indirect antibody approach.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Phosphorylation sites on tau by tau protein kinase I, a bovine derived kinase generating an epitope of paired helical filaments

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Fetal-type phosphorylation of the tau in paired helical filaments

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The extent of phosphorylation of fetal tau is comparable to that of PHF-tau from Alzheimer paired helical filaments

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid beta-protein precursor is associated with extracellular matrix

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Retinoic acid induced differentiated neuroblastoma cells show increased expression of the beta A4 amyloid gene of Alzheimer's disease and an altered splicing pattern

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Alzheimer disease proteins (A68) share epitopes with tau but show distinct biochemical properties

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Phosphate analysis and dephosphorylation of modified tau associated with paired helical filaments

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Phosphorylation-dependent epitopes of neurofilament antibodies on tau protein and relationship with Alzheimer tau

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

p44mpk MAP kinase induces Alzheimer type alterations in tau function and in primary hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Reversible in vitro growth of Alzheimer disease beta-amyloid plaques by deposition of labeled amyloid peptide

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Effect of beta amyloid peptides on neurons in hippocampal slice cultures

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Deposition of amyloid (A4) protein within the brains of persons with dementing disorders other than Alzheimer's disease and Down's syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Senile dementia of Alzheimer type characterized by laminar neuronal loss exclusively in the hippocampus, parahippocampus and medial occipitotemporal cortex.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Genetic and molecular advances in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid beta-protein precursor deposition in rat hippocampus lesioned by ibotenic acid injection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Increased senile plaques without microglia in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Developmental and differential expression of beta amyloid protein precursor mRNAs in mouse brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Synthetic amyloid beta-protein fails to produce specific neurotoxicity in monkey cerebral cortex

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Deposition of ?/A4 protein along neuronal plasma membranes in diffuse senile plaques

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Fibroblast growth factor induces β-amyloid precursor mRNA in glial but not neuronal cultured cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Brain protein kinase PK40erk converts TAU into a PHF-like form as found in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Beta-amyloid from Alzheimer disease brains inhibits sprouting and survival of sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Intracerebral beta-amyloid(25-35) produces tissue damage: is it neurotoxic?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Neuronal pathology in the nucleus basalis and associated cell groups in senile dementia of the Alzheimer's type: possible role in cell loss

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid beta protein precursor is a mitogen

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Phosphorylation of tau by proline-directed protein kinase (p34cdc2/p58cyclin A) decreases tau-induced microtubule assembly and antibody SMI33 reactivity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

β-Amyloid precursor protein gene is differentially expressed in axotomized sensory and motor systems

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The molecular pathology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Beta-amyloid precursor protein cleavage by a membrane-bound protease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

NGF deprivation and neuronal degeneration trigger altered beta-amyloid precursor protein gene expression in the rat superior cervical ganglia in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Nerve growth factor-induced neuronal differentiation is accompanied by differential splicing of beta-amyloid precursor mRNAs in the PC12 cell line

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Failure of beta-amyloid protein fragment 25-35 to cause hippocampal damage in the rat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Toxic effect of a beta-amyloid peptide (beta 22-35) on the hippocampal neuron and its prevention

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Observations on the brains of demented old people

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Characterization of beta-amyloid peptide from human cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Amyloid beta protein enhances the survival of hippocampal neurons in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Messenger RNAs of beta-amyloid precursor protein and prion protein are regulated by nerve growth factor in PC12 cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Subunit structure of paired helical filaments in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Phosphorylation of protein tau by double-stranded DNA-dependent protein kinase.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Immunoelectron microscopic localization of amyloid beta protein in the diffuse plaques of Alzheimer-type dementia.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Protein kinase FA/GSK-3 phosphorylates tau on Ser235-Pro and Ser404-Pro that are abnormally phosphorylated in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.1994.TB00977.X

21 January 2018

Identifiers

10.1111/J.1365-2990.1994.TB00977.X

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

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