(Q53180704)

12 May 2018

title

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments. (English)

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12 May 2018

1

Haass C

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12 May 2018

author name string

Koo EH

2

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12 May 2018

Mellon A

3

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12 May 2018

Hung AY

4

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12 May 2018

Selkoe DJ

5

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12 May 2018

language of work or name

English

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publication date

1 June 1992

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12 May 2018

published in

Nature

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12 May 2018

volume

357

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12 May 2018

issue

6378

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12 May 2018

page(s)

500-503

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12 May 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

cites work

1 reference

7 January 2021

Cleavage of amyloid beta peptide during constitutive processing of its precursor

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Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

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7 January 2021

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

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7 January 2021

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

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7 January 2021

Human vascular endothelial cells in culture. Growth and DNA synthesis

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7 January 2021

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

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7 January 2021

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

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7 January 2021

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

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7 January 2021

Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion

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7 January 2021

NEW CYTOPLASMIC COMPONENTS IN ARTERIAL ENDOTHELIA

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7 January 2021

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

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7 January 2021

pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells

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7 January 2021

Identification of a stable fragment of the Alzheimer amyloid precursor containing the beta-protein in brain microvessels

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7 January 2021

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

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7 January 2021

The amyloid precursor protein is concentrated in neuronal lysosomes in normal and Alzheimer disease subjects.

1 reference

7 January 2021

Evidence for lysosomal processing of amyloid beta-protein precursor in cultured cells.

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7 January 2021

Increased release of an amyloidogenic C-terminal Alzheimer amyloid precursor protein fragment from stressed PC-12 cells

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7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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7 January 2021

Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant

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7 January 2021

Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line

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7 January 2021

Isolation of subcellular organelles

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7 January 2021

Identifiers

DOI

10.1038/357500A0

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12 May 2018

Dimensions Publication ID

1017658082

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12 May 2018