(Q46797123)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15745955%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons (English)

1 reference

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9 January 2020

4

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9 January 2020

author name string

Pablo Helguera

1

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9 January 2020

Alejandra Pelsman

2

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9 January 2020

Gustavo Pigino

3

1 reference

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9 January 2020

Elizabeth Head

5

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9 January 2020

Jorge Busciglio

6

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9 January 2020

language of work or name

English

0 references

publication date

1 March 2005

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9 January 2020

published in

Journal of Neuroscience

1 reference

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9 January 2020

volume

25

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9 January 2020

issue

9

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9 January 2020

page(s)

2295-2303

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Apoptosis-associated proteins p53 and APO-1/Fas (CD95) in brains of adult patients with Down syndrome

9 January 2020

cites work

1 reference

12 December 2020

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

1 reference

12 December 2020

Intraneuronal Abeta42 accumulation in human brain.

1 reference

12 December 2020

Molecular abnormalities of the brain in Down syndrome: relevance to Alzheimer's neurodegeneration

1 reference

12 December 2020

Neuronal cell death in Down's syndrome

1 reference

12 December 2020

Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation.

1 reference

12 December 2020

Ets target genes: past, present and future

1 reference

12 December 2020

Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria

1 reference

12 December 2020

Down syndrome and Alzheimer's disease: a link between development and aging

1 reference

12 December 2020

Ets-2 is induced by oxidative stress and sensitizes cells to H(2)O(2)-induced apoptosis: implications for Down's syndrome

1 reference

12 December 2020

Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome

1 reference

12 December 2020

Beta-amyloid precursor protein, ETS-2 and collagen alpha 1 (VI) chain precursor, encoded on chromosome 21, are not overexpressed in fetal Down syndrome: further evidence against gene dosage effect.

1 reference

12 December 2020

Apoptosis: a link between cancer genetics and chemotherapy

1 reference

12 December 2020

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

1 reference

12 December 2020

Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies

1 reference

12 December 2020

Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain

1 reference

12 December 2020

Characterization of neuronal dystrophy induced by fibrillar amyloid beta: implications for Alzheimer's disease

1 reference

12 December 2020

Beta-amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome

1 reference

12 December 2020

ETS2 overexpression in transgenic models and in Down syndrome predisposes to apoptosis via the p53 pathway

1 reference

12 December 2020

p53 has a direct apoptogenic role at the mitochondria

1 reference

12 December 2020

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

1 reference

12 December 2020

GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons.

1 reference

12 December 2020

Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport

1 reference

12 December 2020

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

12 December 2020

Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins

1 reference

12 December 2020

Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses

1 reference

12 December 2020

Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis.

1 reference

12 December 2020

Temporal cortex hypermetabolism in Down syndrome prior to the onset of dementia

1 reference

12 December 2020

Cell death: critical control points

1 reference

12 December 2020

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

12 December 2020

1 reference

12 December 2020

p53 function and dysfunction

1 reference

12 December 2020

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

1 reference

12 December 2020

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

1 reference

12 December 2020

The neurobiologic consequences of Down syndrome

1 reference

12 December 2020

The pathological association between Down syndrome and Alzheimer disease

1 reference

12 December 2020

Temporal and tissue-specific expression of mouse ets genes

1 reference

12 December 2020

The Ets1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation

1 reference

12 December 2020

Analysis of p53 transactivation through high-affinity binding sites

1 reference

12 December 2020

The Ets family of transcription factors

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12 December 2020

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

1 reference

12 December 2020

Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice

1 reference

12 December 2020

ETS1 and ETS2 in p53 regulation: spatial separation of ETS binding sites (EBS) modulate protein: DNA interaction.

1 reference

12 December 2020

Constitutive overexpression of Cu/Zn superoxide dismutase exacerbates kainic acid-induced apoptosis of transgenic-Cu/Zn superoxide dismutase neurons

1 reference

12 December 2020

Elevation in the ratio of Cu/Zn-superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide.

1 reference

12 December 2020

Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease

1 reference

12 December 2020

Stress, aging, and neurodegenerative disorders. Molecular mechanisms

1 reference

12 December 2020

10.1523/JNEUROSCI.5107-04.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15745955%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15745955%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

15745955

1 reference