(Q35103366)

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Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence

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scholarly article

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Europe PubMed Central

6 August 2017

Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence (English)

1 reference

Europe PubMed Central

6 August 2017

Alzheimer's disease

0 references

author name string

Karen Hoppens Gylys

1

1 reference

Europe PubMed Central

6 August 2017

Jeffrey A Fein

2

1 reference

Europe PubMed Central

6 August 2017

Fusheng Yang

3

1 reference

Europe PubMed Central

6 August 2017

Dorothy J Wiley

4

1 reference

Europe PubMed Central

6 August 2017

Carol A Miller

5

1 reference

Europe PubMed Central

6 August 2017

Gregory M Cole

6

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

1 November 2004

1 reference

Europe PubMed Central

6 August 2017

The American Journal of Pathology

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Europe PubMed Central

6 August 2017

165

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Europe PubMed Central

6 August 2017

5

1 reference

Europe PubMed Central

6 August 2017

1809-1817

1 reference

Europe PubMed Central

6 August 2017

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

1 reference

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9 July 2018

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

1 reference

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9 July 2018

Beta-secretase activity increases with aging in human, monkey, and mouse brain.

1 reference

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9 July 2018

New roles for astrocytes: regulation of CNS synaptogenesis.

1 reference

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9 July 2018

Anatomical aspects of glia-synapse interaction: the perisynaptic glial sheath consists of a specialized astrocyte compartment

1 reference

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9 July 2018

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

1 reference

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9 July 2018

Alzheimer's disease is a synaptic failure

1 reference

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9 July 2018

Do SNARE proteins confer specificity for vesicle fusion?

1 reference

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9 July 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

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9 July 2018

Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome

1 reference

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9 July 2018

Caspases, apoptosis, and Alzheimer disease: causation, correlation, and confusion

1 reference

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9 July 2018

Clustering and anchoring mechanisms of molecular constituents of postsynaptic scaffolds in dendritic spines

1 reference

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9 July 2018

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

1 reference

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9 July 2018

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

1 reference

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9 July 2018

Control of synapse number by glia

1 reference

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9 July 2018

Staging of cytoskeletal and beta-amyloid changes in human isocortex reveals biphasic synaptic protein response during progression of Alzheimer's disease

1 reference

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9 July 2018

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

1 reference

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9 July 2018

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

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9 July 2018

Intraneuronal Abeta42 accumulation in human brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618663

9 July 2018

"Apoptotic" biochemical cascades in synaptic compartments: roles in adaptive plasticity and neurodegenerative disorders

1 reference

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9 July 2018

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

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9 July 2018

Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis

1 reference

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9 July 2018

Brain spectrin binding to the NMDA receptor is regulated by phosphorylation, calcium and calmodulin

1 reference

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9 July 2018

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

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9 July 2018

Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease

1 reference

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9 July 2018

Synaptic efficacy enhanced by glial cells in vitro.

1 reference

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9 July 2018

Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618663

9 July 2018

Is the "preamyloid" of diffuse plaques in Alzheimer's disease really nonfibrillar?

1 reference

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9 July 2018

The glutamatergic nerve terminal

1 reference

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9 July 2018

The synaptic vesicle cycle: a cascade of protein-protein interactions

1 reference

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9 July 2018

Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95

1 reference

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A rapid method for preparing synaptosomes: comparison, with alternative procedures.

1 reference

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9 July 2018

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

1 reference

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9 July 2018

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

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A gentle fixation and permeabilization method for combined cell surface and intracellular staining with improved precision in DNA quantification

1 reference

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9 July 2018

Enrichment of presynaptic and postsynaptic markers by size-based gating analysis of synaptosome preparations from rat and human cortex

1 reference

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27 September 2018

Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

1 reference

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27 September 2018

The impact of Aβ-plaques on cortical cholinergic and non-cholinergic presynaptic boutons in alzheimer's disease-like transgenic mice

1 reference

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27 September 2018

Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice.

1 reference

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27 September 2018

Apolipoprotein E enhances uptake of soluble but not aggregated amyloid-beta protein into synaptic terminals

1 reference

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Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis.

1 reference

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27 September 2018

Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice.

1 reference

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Caspase inhibition protects nerve terminals from in vitro degradation

1 reference

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Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

1 reference

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Interactions of amyloid beta-protein with various gangliosides in raft-like membranes: importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid

1 reference

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Maintained synaptophysin immunoreactivity in Tg2576 transgenic mice during aging: correlations with cognitive impairment.

1 reference

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Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease

1 reference

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Quantitative characterization of crude synaptosomal fraction (P-2) components by flow cytometry

1 reference

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Loss of proteins regulating synaptic plasticity in normal aging of the human brain and in Alzheimer disease.

1 reference

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1 reference

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Synaptic and neuritic alterations during the progression of Alzheimer's disease

1 reference

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27 September 2018

GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618663

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Synaptic remodelling and astrocytic hypertrophy in rat cerebral cortex from early to late adulthood.

1 reference

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27 September 2018

Polyclonals to beta-amyloid(1-42) identify most plaque and vascular deposits in Alzheimer cortex, but not striatum

1 reference

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7 January 2021

Choline Uptake and Acetylcholine Synthesis in Synaptosomes: Investigations Using Two Different Labeled Variants of Choline

1 reference

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7 January 2021

mRNA at the synapse: analysis of a synaptosomal preparation enriched in hippocampal dendritic spines

1 reference

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7 January 2021

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

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1 reference

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12 December 2020

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10.1016/S0002-9440(10)63436-0

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

ResearchGate publication ID

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