(Q44604510)

4 December 2017

title

The impact of Abeta-plaques on cortical cholinergic and non-cholinergic presynaptic boutons in alzheimer's disease-like transgenic mice (English)

1 reference

4 December 2017

The impact of Aβ-plaques on cortical cholinergic and non-cholinergic presynaptic boutons in alzheimer's disease-like transgenic mice (English)

1 reference

https://api.crossref.org/works/10.1016/S0306-4522(03)00394-4

16 March 2024

0 references

2

T. P. Wong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14522000

16 March 2024

5

A. C. Cuello

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14522000

16 March 2024

author name string

Bell KF

4

1 reference

4 December 2017

L. Hu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14522000

16 March 2024

S. L. Côté

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14522000

16 March 2024

K. F S. Bell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14522000

16 March 2024

language of work or name

English

0 references

publication date

1 January 2003

1 reference

full work available at URL

4 December 2017

https://api.elsevier.com/content/article/PII:S0306452203003944?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0306-4522(03)00394-4

https://api.elsevier.com/content/article/PII:S0306452203003944?httpAccept=text/plain

16 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0306-4522(03)00394-4

16 March 2024

1 reference

4 December 2017

volume

121

1 reference

4 December 2017

issue

2

1 reference

4 December 2017

page(s)

421-432

1 reference

Rivastigmine for Alzheimer's disease: Canadian interpretation of intermediate outcome measures and cost implications

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Choline acetyltransferase activity and histopathology of frontal neocortex from biopsies of demented patients

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

The effects of donepezil in Alzheimer's disease - results from a multinational trial.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Rapid onset of neuronal death induced by blockade of either axoplasmic transport or action potentials in afferent fibers during brain development

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Cholinergic function and intellectual decline in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

The neuropsychology of preclinical Alzheimer's disease and mild cognitive impairment

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Alzheimer's disease: etiologies, pathophysiology, cognitive reserve, and treatment opportunities

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Impaired axonal transport of cortical neurons in Alzheimer's disease is associated with neuropathological changes

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Selective loss of central cholinergic neurons in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Cholinergic markers in elderly patients with early signs of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Acetylcholinesterase inhibitors in the treatment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Tetrahydroaminoacridine-lecithin combination treatment in patients with intermediate-stage Alzheimer's disease. Results of a Canadian double-blind, crossover, multicenter study.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Functional, cognitive and behavioral effects of donepezil in patients with moderate Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Relationship between plaques, tangles, and loss of cortical cholinergic fibers in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Selective inhibitors of butyrylcholinesterase: a valid alternative for therapy of Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Cerebral cortex pathology in aging and Alzheimer's disease: a quantitative survey of large hospital-based geriatric and psychiatric cohorts

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Synaptic loss in Alzheimer's disease and other dementias

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Survival and plasticity of basal forebrain cholinergic systems in mice transgenic for presenilin-1 and amyloid precursor protein mutant genes

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Regional synaptic pathology in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

A 38,000-dalton membrane protein (p38) present in synaptic vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Cholinergic depletion prevents expansion of topographic maps in somatosensory cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Cortical map reorganization enabled by nucleus basalis activity

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Pharmacological drug treatment of Alzheimer disease: the cholinergic hypothesis revisited.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Synaptic pathology in Alzheimer's disease: immunological data for markers of synaptic and large dense-core vesicles.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Alzheimer's disease and aging: effects on perforant pathway perikarya and synapses

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Endocrine secretory granules and neuronal synaptic vesicles have three integral membrane proteins in common

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Neuroimmune mechanisms in Alzheimer disease pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Preferential synaptic relationships between substance P-immunoreactive boutons and neurokinin 1 receptor sites in the rat spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Immunocytochemical localization of neurokinin B in the rat spinal dorsal horn and its association with substance P and GABA: an electron microscopic study

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Mild cognitive impairment represents early-stage Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Loss of muscarinic M4 receptors in hippocampus of Alzheimer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Convergent cholinergic activities in aging and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Mutant genes in familial Alzheimer's disease and transgenic models

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Neurotransmitter and receptor deficits in senile dementia of the Alzheimer type

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Differential distribution of the putative vesicular transporter for acetylcholine in the rat central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Quantitative assessment of cortical synaptic density in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Amyloid beta-protein precursor: new clues to the genesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Development of a mouse antiperoxidase secreting hybridoma for use in the production of a mouse PAP complex for immunocytochemistry and as a parent cell line in the development of hybrid hybridomas

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Proteins of synaptic vesicles involved in exocytosis and membrane recycling

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Characterization of muscarinic receptor subtypes in Alzheimer and control brain cortices by selective muscarinic antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Effects of muscarinic blockade in perirhinal cortex during visual recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Mild cognitive impairment: a clinically useful but currently ill-defined concept?

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Molecular biology of the vesicular ACh transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Quantitation of nerve terminal populations: synaptic vesicle-associated proteins as markers for synaptic density in the rat neostriatum

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervation

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Amyloid precursor protein potentiates the neurotrophic activity of NGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Amyloid precursor protein requires the insulin signaling pathway for neurotrophic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Essential role of neocortical acetylcholine in spatial memory

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Synaptic numbers across cortical laminae and cognitive performance of the rat during ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Modeling the prevalence and incidence of Alzheimer's disease and mild cognitive impairment.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900394-4

7 January 2021

Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer' disease

34

1 reference

https://api.crossref.org/works/10.1016/S0306-4522(03)00394-4

Immunocytochemical methods

16 March 2024

73

1 reference

https://api.crossref.org/works/10.1016/S0306-4522(03)00394-4

16 March 2024

Identifiers

1 reference

4 December 2017

1 reference