(Q28486228)

English

Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production

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scholarly article

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Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production (English)

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1 reference

based on heuristic

inferred from title

admixture mapping

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Marta E Alarcón-Riquelme

30

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Joel M Guthridge

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Joel M Guthridge

26

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Jennifer A Kelly

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Jennifer A Kelly

9

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Timothy B. Niewold

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Timothy B Niewold

10

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Robert P. Kimberly

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Robert P Kimberly

36

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Jason H Moore

23

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Julio E. Molineros

1

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Molineros JE

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2

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Maiti AK

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Sun C

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Looger LL

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5

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Han S

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Xana R Kim-Howard

6

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Kim-Howard X

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7

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Glenn S

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8

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Adler A

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Gary S. Gilkeson

11

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Gilkeson GS

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12

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Brown EE

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Graciela S Alarcón

13

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Alarcón GS

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14

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Edberg JC

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Michelle A. Petri

15

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Petri M

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Rosalind Ramsey-Goldman

16

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Ramsey-Goldman R

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John D Reveille

17

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Reveille JD

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Vilá LM

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Freedman BI

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Tsao BP

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Lindsey A. Criswell

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Criswell LA

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Jacob CO

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24

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Vyse TJ

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25

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Langefeld CL

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Patrick M Gaffney

27

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Gaffney PM

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28

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Moser KL

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Robert Hal Scofield

29

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Scofield RH

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Scott M. Williams

31

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Williams SM

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32

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Merrill JT

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Judith A. James

33

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James JA

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Kenneth M Kaufman

34

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Kaufman KM

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37

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Harley JB

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38

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Nath SK

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language of work or name

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publication date

2013

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9

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2

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e1003222

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copyright license

Creative Commons Attribution 4.0 International

18 February 2013

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April 2022 Public Data File from Crossref

copyright status

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Structural basis of RNA recognition and activation by innate immune receptor RIG-I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Admixture mapping comes of age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

The Interferon Stimulator Mitochondrial Antiviral Signaling Protein Facilitates Cell Death by Disrupting the Mitochondrial Membrane Potential and by Activating Caspases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

MYH9 is associated with nondiabetic end-stage renal disease in African Americans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

The NCBI dbGaP database of genotypes and phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Clustal W and Clustal X version 2.0

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Population structure and eigenanalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

A High-Density Admixture Map for Disease Gene Discovery in African Americans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Methods for high-density admixture mapping of disease genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Design and analysis of admixture mapping studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

The International HapMap Project

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

The structure of haplotype blocks in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Inference of population structure using multilocus genotype data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

New approaches to disease mapping in admixed populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

19 March 2017

Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

7 April 2017

GCTA: a tool for genome-wide complex trait analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

7 April 2017

Detecting the number of clusters of individuals using the software STRUCTURE: a simulation study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

7 April 2017

The 1982 revised criteria for the classification of systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

7 April 2017

Genotype imputation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

7 April 2017

Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

7 April 2017

Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

The landscape of recombination in African Americans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Reduced expression of IFIH1 is protective for type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Carriers of rare missense variants in IFIH1 are protected from psoriasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

CENTROIDFOLD: a web server for RNA secondary structure prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Pathogen recognition in the innate immune response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Non-homologous end joining in class switch recombination: the beginning of the end

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Genomic polymorphism at the interferon-induced helicase (IFIH1) locus contributes to Graves' disease susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Admixture mapping as a tool in gene discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

WHAP: haplotype-based association analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Activation of Ras/Raf protects cells from melanoma differentiation-associated gene-5-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Measures of human population structure show heterogeneity among genomic regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Will admixture mapping work to find disease genes?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Statistical tests for admixture mapping with case-control and cases-only data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

The clinical value of intracellular autoantigens B-cell epitopes in systemic rheumatic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Genomic structure, organisation, and promoter analysis of the bovine (Bos taurus) Mx1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Use of unlinked genetic markers to detect population stratification in association studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Nucleolin is one component of the B cell-specific transcription factor and switch region binding protein, LR1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

The murine nucleolin protein is an inducible DNA and ATP binding protein which is readily detected in nuclear extracts of lipopolysaccharide-treated splenocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Interrelations between the maturation of a 100 kDa nucleolar protein and pre rRNA synthesis in CHO cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Estimating the population attributable risk for multiple risk factors using case-control data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

29 September 2017

The selective footprints of viral pressures at the human RIG-I-like receptor family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

2 June 2018

Use and misuse of population attributable fractions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

2 June 2018

Autoantibodies to nucleolin in systemic lupus erythematosus and other diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575474

2 June 2018

Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003222

21 January 2018

Population genetics of IFIH1: ancient population structure, local selection, and implications for susceptibility to type 1 diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003222

21 January 2018

Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003222

21 January 2018

Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003222

21 January 2018

Decreased expressions of the TNF-alpha signaling adapters in peripheral blood mononuclear cells (PBMCs) are correlated with disease activity in patients with systemic lupus erythematosus.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003222

21 January 2018

Fine points in mapping autoimmunity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003222

21 January 2018

Nucleolin is a sequence-specific RNA-binding protein: characterization of targets on pre-ribosomal RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/23441136

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFIH1 gene polymorphisms in type 1 diabetes: genetic association analysis and genotype-phenotype correlation in the Belgian population

1 reference

https://pubmed.ncbi.nlm.nih.gov/23441136

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type I IFN induction via targeting to static early endosome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23441136

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PGEN.1003222

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Semantic Scholar paper ID

5016ba5bc6bdf789b431c40680020652e2185ab1

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