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Munc18c depletion selectively impairs the sustained phase of insulin release
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
title
Munc18c depletion selectively impairs the sustained phase of insulin release
(English)
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
main subject
Vesicle-associated membrane protein 2
1 reference
stated in
GOA release 2020-03-11
Syntaxin 4A (placental)
1 reference
stated in
GOA release 2020-03-11
Syntaxin binding protein 3
1 reference
stated in
GOA release 2020-03-11
preproinsulin
1 reference
based on heuristic
inferred from title
author name string
Eunjin Oh
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
Debbie C. Thurmond
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
language of work or name
English
0 references
publication date
1 May 2009
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
published in
Diabetes
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
volume
58
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
issue
5
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
page(s)
1165–1174
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
copyright license
Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported
start time
27 August 2021
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
19 March 2017
Munc18-1 expression levels control synapse recovery by regulating readily releasable pool size
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
19 March 2017
Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
19 March 2017
Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization
1 reference
stated in
PubMed Central
reference URL
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retrieved
19 March 2017
A direct interaction between Cdc42 and vesicle-associated membrane protein 2 regulates SNARE-dependent insulin exocytosis
1 reference
stated in
PubMed Central
reference URL
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retrieved
19 March 2017
A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells
1 reference
stated in
PubMed Central
reference URL
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retrieved
19 March 2017
Munc18-1 promotes large dense-core vesicle docking
1 reference
stated in
PubMed Central
reference URL
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19 March 2017
Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
19 March 2017
DOC2 proteins in rat brain: complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
19 March 2017
Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
19 March 2017
Phosphorylation of Munc-18/n-Sec1/rbSec1 by protein kinase C: its implication in regulating the interaction of Munc-18/n-Sec1/rbSec1 with syntaxin
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
19 March 2017
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
SNAREs--engines for membrane fusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
7 April 2017
Skeletal muscle munc18c and syntaxin 4 in human obesity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Munc 18-1 and granuphilin collaborate during insulin granule exocytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Temporal dynamics of tyrosine phosphorylation in insulin signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Caveolin-1 functions as a novel Cdc42 guanine nucleotide dissociation inhibitor in pancreatic beta-cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
The stimulus-induced tyrosine phosphorylation of Munc18c facilitates vesicle exocytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
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29 September 2017
Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
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29 September 2017
Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Defects in synaptic vesicle docking in unc-18 mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
A rat brain Sec1 homologue related to Rop and UNC18 interacts with syntaxin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Pancreatic islet glucose metabolism and regulation of insulin secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
29 September 2017
Biphasic insulin secretion from freshly isolated or cultured, perifused rodent islets: comparative studies with rats and mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
2 June 2018
Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
2 June 2018
Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
2 June 2018
Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
2 June 2018
The RalA GTPase is a central regulator of insulin exocytosis from pancreatic islet beta cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
27 November 2018
Search for genetic variants of the SYNTAXIN 1A (STX1A) gene: the -352 A>T variant in the STX1A promoter associates with impaired glucose metabolism in an Italian obese population
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
27 November 2018
Dissecting docking and tethering of secretory vesicles at the target membrane.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
27 November 2018
In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse: pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
27 November 2018
Insulin secretion in the conscious mouse is biphasic and pulsatile
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
27 November 2018
Syntaxin 4 facilitates biphasic glucose-stimulated insulin secretion from pancreatic beta-cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
27 November 2018
Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
27 November 2018
Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
27 November 2018
Insulin resistance in tetracycline-repressible Munc18c transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671048
retrieved
27 November 2018
Nutrient control of insulin secretion in isolated normal human islets
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19188424
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Alcohol/cholecystokinin-evoked pancreatic acinar basolateral exocytosis is mediated by protein kinase C alpha phosphorylation of Munc18c
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19188424
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Single nucleotide polymorphism (D68D, T to C) in the syntaxin 1A gene correlates to age at onset and insulin requirement in Type II diabetic patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19188424
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Intracellular ATP directly blocks K+ channels in pancreatic B-cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19188424
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Voltage-gated Ca2+ current in pancreatic B-cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19188424
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Munc13-1 is required for the sustained release of insulin from pancreatic beta cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19188424
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.2337/DB08-1059
0 references
PMCID
2671048
0 references
PubMed ID
19188424
1 reference
stated in
PubMed
PubMed ID
19188424
retrieved
24 January 2017
ResearchGate publication ID
23972527
0 references
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