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Dynein light chain Tctex-type 1 modulates orexin signaling through its interaction with orexin 1 receptor
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scholarly article
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PubMed
PubMed ID
22028875
retrieved
24 January 2017
title
Dynein light chain Tctex-type 1 modulates orexin signaling through its interaction with orexin 1 receptor
(English)
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PubMed
PubMed ID
22028875
retrieved
24 January 2017
main subject
Dynein light chain Tctex-type 1F
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GOA release 2020-03-11
Dynein light chain Tctex-type 3
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GOA release 2020-03-11
Hypocretin (orexin) receptor 2
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GOA release 2020-03-11
Hypocretin (orexin) receptor 1
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GOA release 2020-03-11
author
Nicolas Cermakian
series ordinal
6
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Valérie Mongrain
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3
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Valérie Mongrain
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PubMed
PubMed ID
22028875
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24 January 2017
author name string
David Duguay
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1
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PubMed
PubMed ID
22028875
retrieved
24 January 2017
Erika Bélanger-Nelson
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2
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PubMed
PubMed ID
22028875
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24 January 2017
Anna Beben
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4
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PubMed
PubMed ID
22028875
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24 January 2017
Armen Khatchadourian
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5
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PubMed
PubMed ID
22028875
retrieved
24 January 2017
language of work or name
English
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publication date
1 January 2011
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PubMed
PubMed ID
22028875
retrieved
24 January 2017
published in
PLOS One
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PubMed
PubMed ID
22028875
retrieved
24 January 2017
volume
6
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PubMed
PubMed ID
22028875
retrieved
24 January 2017
page(s)
e26430
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PubMed
PubMed ID
22028875
retrieved
24 January 2017
issue
10
1 reference
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PubMed
PubMed ID
22028875
retrieved
24 January 2017
copyright license
Creative Commons Attribution 4.0 International
start time
20 October 2011
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April 2022 Public Data File from Crossref
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copyrighted
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cites work
Structural and thermodynamic characterization of a cytoplasmic dynein light chain intermediate chain complex
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G protein beta gamma subunit interaction with the dynein light-chain component Tctex-1 regulates neurite outgrowth
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PubMed Central
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Differential regulation of the human adrenocorticotropin receptor [melanocortin-2 receptor (MC2R)] by human MC2R accessory protein isoforms alpha and beta in isogenic human embryonic kidney 293 cells
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The DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3
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Cytoplasmic dynein nomenclature
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PubMed Central
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19 March 2017
OX1 orexin receptors couple to adenylyl cyclase regulation via multiple mechanisms
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Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins
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PubMed Central
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Subunit heterogeneity of cytoplasmic dynein: Differential expression of 14 kDa dynein light chains in rat hippocampus
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Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport
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19 March 2017
Structure of Tctex-1 and its interaction with cytoplasmic dynein intermediate chain
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197643
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19 March 2017
Receptor-independent activators of heterotrimeric G-protein signaling pathways
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19 March 2017
The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
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PubMed Central
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Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1
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Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
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Microtubule polymerization dynamics
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19 March 2017
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity
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PubMed Central
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19 March 2017
A novel genetic system to detect protein-protein interactions
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19 March 2017
Endocytosis and signalling: intertwining molecular networks
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7 April 2017
Neural substrates of awakening probed with optogenetic control of hypocretin neurons
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7 April 2017
Hypothalamic regulation of sleep and circadian rhythms
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7 April 2017
Neurons containing hypocretin (orexin) project to multiple neuronal systems
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Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling
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9 May 2017
Evidence for the involvement of Lfc and Tctex-1 in axon formation
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29 September 2017
Fine-tuning of GPCR activity by receptor-interacting proteins
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Sleep homeostasis modulates hypocretin-mediated sleep-to-wake transitions
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29 September 2017
Biomedical application of orexin/hypocretin receptor ligands in neuroscience
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29 September 2017
The brain hypocretins and their receptors: mediators of allostatic arousal.
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29 September 2017
The role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexes
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Cargo transport: molecular motors navigate a complex cytoskeleton
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A hallmark of immunoreceptor, the tyrosine-based inhibitory motif ITIM, is present in the G protein-coupled receptor OX1R for orexins and drives apoptosis: a novel mechanism.
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29 September 2017
The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation.
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29 September 2017
Cytoplasmic dynein mediates adenovirus binding to microtubules
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29 September 2017
Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension
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29 September 2017
Orexins and their receptors: structural aspects and role in peripheral tissues.
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29 September 2017
Functions of the orexinergic/hypocretinergic system
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29 September 2017
Visualizing differences in ligand-induced beta-arrestin-GFP interactions and trafficking between three recently characterized G protein-coupled receptors
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29 September 2017
Fos expression in orexin neurons varies with behavioral state.
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29 September 2017
The dynein microtubule motor
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29 September 2017
Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
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29 September 2017
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29 September 2017
Interaction of p59fyn kinase with the dynein light chain, Tctex-1, and colocalization during cytokinesis
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29 September 2017
Isolated flagellar outer arm dynein translocates brain microtubules in vitro.
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2 June 2018
Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis.
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27 November 2018
Different microtubule motors move early and late endocytic compartments.
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27 November 2018
OX1 orexin receptors activate extracellular signal-regulated kinase in Chinese hamster ovary cells via multiple mechanisms: the role of Ca2+ influx in OX1 receptor signaling.
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27 November 2018
A role for lateral hypothalamic orexin neurons in reward seeking
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27 November 2018
Behavioral correlates of activity in identified hypocretin/orexin neurons
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27 November 2018
Crystal structure of dynein light chain TcTex-1.
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27 November 2018
PTH/PTH-related protein receptor interacts directly with Tctex-1 through its COOH terminus
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PubMed Central
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27 November 2018
Differential expression of orexin receptors 1 and 2 in the rat brain.
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27 November 2018
Hypocretin (orexin) deficiency in human narcolepsy.
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PubMed Central
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27 November 2018
Solution structure of the Tctex1 dimer reveals a mechanism for dynein-cargo interactions
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22028875
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of the dynein light chains required for human papillomavirus infection
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22028875
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1371/JOURNAL.PONE.0026430
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ADS bibcode
2011PLoSO...626430D
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PMCID
3197643
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PubMed ID
22028875
1 reference
stated in
PubMed
PubMed ID
22028875
retrieved
24 January 2017
ResearchGate publication ID
51746799
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