(Q28506246)

24 January 2017

title

Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine (English)

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Dimethylarginine dimethylaminohydrolase 1

24 January 2017

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GOA release 2020-03-11

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8

Edzard Schwedhelm

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author name string

Xinli Hu

1

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24 January 2017

Dorothee Atzler

2

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24 January 2017

Xin Xu

3

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24 January 2017

Ping Zhang

4

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24 January 2017

Haipeng Guo

5

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24 January 2017

Zhongbing Lu

6

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24 January 2017

John Fassett

7

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24 January 2017

Edzard Schwedhelm

8

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24 January 2017

Rainer H. Böger

9

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24 January 2017

Robert J. Bache

10

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24 January 2017

Yingjie Chen

11

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24 January 2017

language of work or name

English

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publication date

1 July 2011

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Arteriosclerosis, Thrombosis, and Vascular Biology

24 January 2017

published in

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24 January 2017

volume

31

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24 January 2017

issue

7

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24 January 2017

page(s)

1540–1546

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Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production

24 January 2017

cites work

1 reference

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Disruption of methylarginine metabolism impairs vascular homeostasis

19 March 2017

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Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases

19 March 2017

1 reference

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Reduced urinary excretion of nitric oxide metabolites and increased plasma levels of asymmetric dimethylarginine in men with essential hypertension

19 March 2017

1 reference

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Endogenous Dimethylarginine as an Inhibitor of Nitric Oxide Synthesis

19 March 2017

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NO-synthase independent NO generation in mammals

19 March 2017

1 reference

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Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus

29 September 2017

1 reference

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Oxidative stress regulates left ventricular PDE5 expression in the failing heart

29 September 2017

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Vascular endothelial-specific dimethylarginine dimethylaminohydrolase-1-deficient mice reveal that vascular endothelium plays an important role in removing asymmetric dimethylarginine

29 September 2017

1 reference

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Role of dimethylarginine dimethylaminohydrolases in the regulation of endothelial nitric oxide production

29 September 2017

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Protein S-nitrosylation in health and disease: a current perspective

29 September 2017

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Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community

29 September 2017

1 reference

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Adenosine A3 receptor deficiency exerts unanticipated protective effects on the pressure-overloaded left ventricle

29 September 2017

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Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems

29 September 2017

1 reference

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The L-arginine paradox: Importance of the L-arginine/asymmetrical dimethylarginine ratio

29 September 2017

1 reference

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Adventures in vascular biology: a tale of two mediators

29 September 2017

1 reference

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DDAH gene and cardiovascular risk

29 September 2017

1 reference

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Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms

29 September 2017

1 reference

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Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence

29 September 2017

1 reference

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Purification and properties of a new enzyme, NG,NG-dimethylarginine dimethylaminohydrolase, from rat kidney

29 September 2017

1 reference

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Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations

29 September 2017

1 reference

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Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins

29 September 2017

1 reference

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Increased endogenous nitric oxide synthase inhibitor in patients with congestive heart failure

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Regional and cardiac haemodynamic effects of NG, NG,dimethyl-L-arginine and their reversibility by vasodilators in conscious rats

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

2 June 2018

1 reference

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Metabolism of NG,NG-and NG,N'G-dimethylarginine in rats

2 June 2018

1 reference

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A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

A role for Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) in mammalian development

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Immunolocalisation and activity of DDAH I and II in the heart and modification post-myocardial infarction.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Asymmetric dimethylarginine independently predicts fatal and nonfatal myocardial infarction and stroke in women: 24-year follow-up of the population study of women in Gothenburg

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Effects of L-arginine on cerebral blood flow, microvascular permeability, number of perfused capillaries, and brain water content in the traumatized mouse brain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Asymmetric dimethylarginine (ADMA) as a risk marker for stroke and TIA in a Swedish population

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Dimethylarginine dimethylaminohydrolase and endothelial dysfunction in failing hearts

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117037

Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

27 November 2018

1 reference

12 December 2020

Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases

1 reference

12 December 2020

Association of homocysteine and asymmetric dimethylarginine with atherosclerosis and cardiovascular events in maintenance hemodialysis patients

1 reference

12 December 2020

High-throughput liquid chromatographic-tandem mass spectrometric determination of arginine and dimethylated arginine derivatives in human and mouse plasma

1 reference

12 December 2020

A stable-isotope based technique for the determination of dimethylarginine dimethylaminohydrolase (DDAH) activity in mouse tissue

1 reference

12 December 2020

Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury

1 reference

12 December 2020

Isoform-specific regulation by N(G),N(G)-dimethylarginine dimethylaminohydrolase of rat serum asymmetric dimethylarginine and vascular endothelium-derived relaxing factor/NO

1 reference

12 December 2020

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

1 reference

12 December 2020

Dimethylarginine:pyruvate aminotransferase in rats. Purification, properties, and identity with alanine:glyoxylate aminotransferase 2

1 reference

12 December 2020

10.1161/ATVBAHA.110.222638

Identifiers

DOI

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