(Q28506609)

24 January 2017

title

Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis (English)

1 reference

WD repeat domain, phosphoinositide interacting 1

24 January 2017

main subject

1 reference

Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha

GOA release 2020-03-11

1 reference

Phosphatidylinositol 3-kinase catalytic subunit type 3

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

8

Pietro De Camilli

1 reference

24 January 2017

Kelly Devereaux

1

1 reference

24 January 2017

Claudia Dall'Armi

2

1 reference

24 January 2017

Abel Alcazar-Roman

3

1 reference

24 January 2017

Yuta Ogasawara

4

1 reference

24 January 2017

Xiang Zhou

5

1 reference

24 January 2017

Fan Wang

6

1 reference

24 January 2017

Akitsugu Yamamoto

7

1 reference

24 January 2017

Gilbert Di Paolo

9

1 reference

24 January 2017

language of work or name

English

0 references

publication date

1 January 2013

1 reference

24 January 2017

2013

0 references

1 reference

24 January 2017

volume

8

1 reference

24 January 2017

issue

10

1 reference

24 January 2017

page(s)

e76405

1 reference

Creative Commons Attribution 4.0 International

24 January 2017

copyright license

start time

3 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3789715/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy

19 March 2017

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Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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7 April 2017

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Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

7 April 2017

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Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

7 April 2017

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Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system

7 April 2017

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29 September 2017

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29 September 2017

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Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34.

29 September 2017

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Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation

29 September 2017

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The role of lipids in the control of autophagy

29 September 2017

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Inositol polyphosphate phosphatases in human disease

29 September 2017

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Phosphatidylinositol-3-phosphate clearance plays a key role in autophagosome completion

29 September 2017

1 reference

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Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis.

29 September 2017

1 reference

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Regulation and cellular functions of class II phosphoinositide 3-kinases.

29 September 2017

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Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

29 September 2017

1 reference

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Lipids in autophagy: constituents, signaling molecules and cargo with relevance to disease.

29 September 2017

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Mechanisms of autophagosome biogenesis

29 September 2017

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Canonical and non-canonical autophagy: variations on a common theme of self-eating?

29 September 2017

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The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Autophagy in the cellular energetic balance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

The phospholipase D1 pathway modulates macroautophagy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Regulation of membrane biogenesis in autophagy via PI3P dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Regulation of autophagy by phosphatidylinositol 3-phosphate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy

29 September 2017

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Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

29 September 2017

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Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

The regulation and function of Class III PI3Ks: novel roles for Vps34.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes

29 September 2017

1 reference

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Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway

29 September 2017

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Individual phosphoinositide 3-kinase C2alpha domain activities independently regulate clathrin function

29 September 2017

1 reference

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An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

29 September 2017

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Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae

29 September 2017

1 reference

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The class III phosphatidylinositol 3-kinase PIK3C3/VPS34 regulates endocytosis and autophagosome-autolysosome formation in podocytes

29 September 2017

1 reference

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Mammalian PIK3C3/VPS34: the key to autophagic processing in liver and heart

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes

2 June 2018

1 reference

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The Hansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue of Saccharomyces cerevisiae Vps34p.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Hydrolysis of phosphatidylinositol 3,4-bisphosphate by inositol polyphosphate 4-phosphatase isolated by affinity elution chromatography

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3789715

Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0076405

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0076405

Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0076405

The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24098492

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0076405

1 reference

ADS bibcode

2013PLoSO...876405D

0 references

1 reference

1 reference

1 reference