(Q28508107)

English

Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway

scientific journal article

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scholarly article

1 reference

24 January 2017

Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway (English)

1 reference

24 January 2017

Mitogen-activated protein kinase kinase 5

1 reference

GOA release 2020-03-11

object named as

Ulrike Mayer

11

1 reference

ORCID Public Data File 2021

Katherine G Finegan

1 reference

ORCID Public Data File 2021

author name string

Xin Wang

1

1 reference

24 January 2017

Anita J. Merritt

2

1 reference

24 January 2017

Jan Seyfried

3

1 reference

24 January 2017

Chun Guo

4

1 reference

24 January 2017

Emmanouil S. Papadakis

5

1 reference

24 January 2017

Katherine G. Finegan

6

1 reference

24 January 2017

Midori Kayahara

7

1 reference

24 January 2017

Jill Dixon

8

1 reference

24 January 2017

Raymond P. Boot-Handford

9

1 reference

24 January 2017

Elizabeth J. Cartwright

10

1 reference

24 January 2017

Cathy Tournier

12

1 reference

24 January 2017

language of work or name

0 references

publication date

1 January 2005

1 reference

24 January 2017

Molecular and Cellular Biology

1 reference

24 January 2017

25

1 reference

24 January 2017

1

1 reference

24 January 2017

336–345

1 reference

24 January 2017

Knockout of ERK5 causes multiple defects in placental and embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Spa2p functions as a scaffold-like protein to recruit the Mpk1p MAP kinase module to sites of polarized growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

ERK5 MAPK regulates embryonic angiogenesis and acts as a hypoxia-sensitive repressor of vascular endothelial growth factor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Big mitogen-activated kinase regulates multiple members of the MEF2 protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Mekk3 is essential for early embryonic cardiovascular development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

MEKK3 directly regulates MEK5 activity as part of the big mitogen-activated protein kinase 1 (BMK1) signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Regulation of the MEF2 family of transcription factors by p38

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Components of a new human protein kinase signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Isolation of MEK5 and differential expression of alternatively spliced forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

19 March 2017

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

7 April 2017

Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

Intestinal stem cells protect their genome by selective segregation of template DNA strands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

Neurotrophins use the Erk5 pathway to mediate a retrograde survival response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

CHAMP, a novel cardiac-specific helicase regulated by MEF2C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

Role of BMK1 in regulation of growth factor-induced cellular responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

Post-translational control of the MEF2A transcriptional regulatory protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

Cardiomyocytes can be generated from marrow stromal cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

Identification of substrates and regulators of the mitogen-activated protein kinase ERK5 using chimeric protein kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

Signal transduction within the nucleus by mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

29 September 2017

Regulation of c-Fos and Fra-1 by the MEK5-ERK5 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

2 June 2018

Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

27 November 2018

Characterization of a neurotrophin signaling mechanism that mediates neuron survival in a temporally specific pattern.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

27 November 2018

Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=538774

27 November 2018

Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/15601854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin Gene Targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/15601854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of bromodeoxyuridine incorporation measurements to the determination of cell distribution within the S phase of the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/15601854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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