(Q28508275)

24 January 2017

title

Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1 (English)

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Glutathione S-transferase, alpha 3

24 January 2017

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GOA release 2020-03-11

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2

Dana Crawford

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24 January 2017

Zoran Ilic

1

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24 January 2017

Dilip Vakharia

series ordinal

3

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24 January 2017

Patricia A. Egner

series ordinal

4

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24 January 2017

Stewart Sell

series ordinal

5

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24 January 2017

publication date

1 February 2010

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Toxicology and Applied Pharmacology

24 January 2017

published in

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24 January 2017

volume

242

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24 January 2017

issue

3

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24 January 2017

page(s)

241–246

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Hepatocellular carcinoma: Epidemiology, risk factors and pathogenesis

24 January 2017

cites work

1 reference

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Physiological role of mGSTA4-4, a glutathione S-transferase metabolizing 4-hydroxynonenal: generation and analysis of mGsta4 null mouse

19 March 2017

1 reference

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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

19 March 2017

1 reference

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Expression of stably transfected murine glutathione S-transferase A3-3 protects against nucleic acid alkylation and cytotoxicity by aflatoxin B1 in hamster V79 cells expressing rat cytochrome P450-2B1

19 March 2017

1 reference

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Determinants of specificity for aflatoxin B1-8,9-epoxide in alpha-class glutathione S-transferases

19 March 2017

1 reference

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Molecular cloning and heterologous expression of a cDNA encoding a mouse glutathione S-transferase Yc subunit possessing high catalytic activity for aflatoxin B1-8,9-epoxide

19 March 2017

1 reference

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Glutathione S-transferases. The first enzymatic step in mercapturic acid formation

19 March 2017

1 reference

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7 April 2017

Glutathione transferases

1 reference

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The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

7 April 2017

1 reference

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The use of glutathione transferase-knockout mice as pharmacological and toxicological models

7 April 2017

1 reference

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Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates

29 September 2017

2 references

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29 September 2017

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Mouse models to study the interaction of risk factors for human liver cancer.

27 November 2018

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Maleylacetoacetate isomerase (MAAI/GSTZ)-deficient mice reveal a glutathione-dependent nonenzymatic bypass in tyrosine catabolism

29 September 2017

1 reference

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Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.

29 September 2017

1 reference

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Role of phase 2 enzyme induction in chemoprotection by dithiolethiones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Interspecies differences in cancer susceptibility and toxicity

29 September 2017

1 reference

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Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress.

29 September 2017

1 reference

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Mutational properties of the primary aflatoxin B1-DNA adduct

29 September 2017

1 reference

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Mechanisms of aflatoxin carcinogenesis

29 September 2017

1 reference

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Risk assessment for aflatoxin: I. Metabolism of aflatoxin B1 by different species

29 September 2017

1 reference

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Contribution of the glutathione S-transferases to the mechanisms of resistance to aflatoxin B1.

29 September 2017

1 reference

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Aflatoxins as risk factors for hepatocellular carcinoma in humans

29 September 2017

1 reference

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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Expression of the murine glutathione S-transferase alpha3 (GSTA3) subunit is markedly induced during adipocyte differentiation: activation of the GSTA3 gene promoter by the pro-adipogenic eicosanoid 15-deoxy-Delta12,14-prostaglandin J2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Quantitative profiling of tissue- and gender-related expression of glutathione S-transferase isoenzymes in the mouse.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Quantitative comparison of covalent aflatoxin-DNA adducts formed in rat and mouse livers and kidneys.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Synergy between hepatitis B virus expression and chemical hepatocarcinogens in transgenic mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Complementary DNA cloning, messenger RNA expression, and induction of alpha-class glutathione S-transferases in mouse tissues

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

The course of CCl4 induced hepatotoxicity is altered in mGSTA4-4 null (-/-) mice

2 June 2018

1 reference

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Low hepatic glutathione S-transferase and increased hepatic DNA adduction contribute to increased tumorigenicity of aflatoxin B1 in newborn and partially hepatectomized mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Role of alpha class glutathione S-transferases as antioxidant enzymes in rodent tissues

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Hepatitis B injury, male gender, aflatoxin, and p53 expression each contribute to hepatocarcinogenesis in transgenic mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Enhanced susceptibility to aflatoxin B1 toxicity in weanling mice pretreated with carbon tetrachloride.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Metabolic basis of the species difference to aflatoxin B1 induced hepatotoxicity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813954

Aflatoxin B 1 , a hepatocarcinogen in the infant mouse

27 November 2018

1 reference

12 December 2020

The comparative metabolism and toxicokinetics of aflatoxin B1 in the monkey, rat, and mouse

1 reference

12 December 2020

Differences in aflatoxin B1-susceptibility of rat and mouse are correlated with the capability in vitro to inactivate aflatoxin B1-epoxide

1 reference

12 December 2020

The mercapturic acid pathway metabolites of a glutathione conjugate of aflatoxin B1

1 reference

12 December 2020

Effect of long-term feeding of nivalenol on aflatoxin B1-initiated hepatocarcinogenesis in mice

1 reference

12 December 2020

Identification of amino acid residues essential for high aflatoxin B1-8,9-epoxide conjugation activity in alpha class glutathione S-transferases through site-directed mutagenesis

1 reference

12 December 2020

Quantification of aflatoxin-B1-N7-Guanine in human urine by high-performance liquid chromatography and isotope dilution tandem mass spectrometry

1 reference

12 December 2020

10.1016/J.TAAP.2009.10.008

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DOI

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