(Q28509001)

24 January 2017

title

Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver (English)

1 reference

Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

24 January 2017

main subject

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GOA release 2020-03-11

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0 references

6

Nancy C. Andrews

1 reference

24 January 2017

Hiromi Gunshin

1

1 reference

24 January 2017

Yuko Fujiwara

2

1 reference

24 January 2017

Angel O. Custodio

3

1 reference

24 January 2017

Cristina Direnzo

4

1 reference

24 January 2017

Sylvie Robine

5

1 reference

24 January 2017

language of work or name

English

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publication date

1 May 2005

1 reference

Journal of Clinical Investigation

24 January 2017

published in

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24 January 2017

volume

115

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24 January 2017

issue

5

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24 January 2017

page(s)

1258–1266

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Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload

24 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

An iron delivery pathway mediated by a lipocalin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Effect of iron deficiency on placental transfer of iron and expression of iron transport proteins in vivo and in vitro

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Identification and localization of divalent metal transporter-1 (DMT-1) in term human placenta

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

The Nramp2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

The C282Y mutation causing hereditary hemochromatosis does not produce a null allele

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Transferrin receptor is necessary for development of erythrocytes and the nervous system

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Mechanisms of cellular iron acquisition: another iron in the fire

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Genes that modify the hemochromatosis phenotype in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Characterization of transferrin-independent iron transport in K562 cells. Unique properties provide evidence for multiple pathways of iron uptake.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Extracellular ferrireductase activity of K562 cells is coupled to transferrin-independent iron transport

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Molecular and cellular mechanisms underlying iron transport deficiency in microcytic anemia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Transferrin receptor 1 is differentially required in lymphocyte development.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

The mammalian transferrin-independent iron transport system may involve a surface ferrireductase activity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1077176

Characterization and genetic studies of microcytic anemia in house mouse

27 November 2018

1 reference

12 December 2020

Low viability, skin lesions, and reduced fertility associated with microcytic anemia in the mouse

1 reference

12 December 2020

Simplified typing of mouse hemoglobin (Hbb) phenotypes using cystamine

1 reference

12 December 2020

An intestinal receptor for heme: Its partial characterization

1 reference

12 December 2020

Characterization of a transferrin-independent uptake system for iron in HeLa cells

1 reference

12 December 2020

Regulation of the transferrin-independent iron transport system in cultured cells

1 reference

12 December 2020

Uptake of non-transferrin-bound iron by both reductive and nonreductive processes is modulated by intracellular iron

1 reference

12 December 2020

Iron homeostasis: insights from genetics and animal models

1 reference

12 December 2020

Cellular localization of divalent metal transporter DMT-1 in rat kidney

1 reference

12 December 2020

Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice

1 reference

12 December 2020

The G185R mutation disrupts function of the iron transporter Nramp2

1 reference

12 December 2020

Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI24356

1 reference

1 reference

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