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Atherosclerosis in LDLR-knockout mice is inhibited, but not reversed, by the PPARgamma ligand pioglitazone
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
title
Atherosclerosis in LDLR-knockout mice is inhibited, but not reversed, by the PPARgamma ligand pioglitazone
(English)
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
main subject
knockout mouse
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Eomesodermin
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GOA release 2020-03-11
atherosclerosis
1 reference
based on heuristic
inferred from title
author name string
Hideaki Nakaya
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
Barbara D. Summers
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
Andrew C. Nicholson
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
Antonio M. Gotto
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
David P. Hajjar
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
Jihong Han
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6
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
language of work or name
English
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publication date
1 June 2009
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stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
published in
The American Journal of Pathology
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
volume
174
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stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
issue
6
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stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
page(s)
2007–2014
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
cites work
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Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes
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19 March 2017
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial
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PubMed Central
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7 April 2017
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
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PubMed Central
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7 April 2017
Pioglitazone inhibits the expression of inflammatory cytokines from both monocytes and lymphocytes in patients with impaired glucose tolerance
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29 September 2017
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29 September 2017
The peroxisome proliferator-activated receptor-gamma agonist pioglitazone represses inflammation in a peroxisome proliferator-activated receptor-alpha-dependent manner in vitro and in vivo in mice.
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PubMed Central
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29 September 2017
HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis
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29 September 2017
Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial
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29 September 2017
PROactive: time for a critical appraisal
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29 September 2017
Pioglitazone stimulates apolipoprotein A-I production without affecting HDL removal in HepG2 cells: involvement of PPAR-alpha
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PubMed Central
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29 September 2017
Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets
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29 September 2017
Insulin resistance and PPAR insulin sensitizers
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29 September 2017
Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line
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29 September 2017
Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice
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PubMed Central
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29 September 2017
Effect of pioglitazone on arteriosclerosis in comparison with that of glibenclamide
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Therapeutic potential of thiazolidinediones in activation of peroxisome proliferator-activated receptor gamma for monocyte recruitment and endothelial regeneration.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Pioglitazone induces plasma platelet activating factor-acetylhydrolase and inhibits platelet activating factor-mediated cytoskeletal reorganization in macrophage
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Clinical, diagnostic, and therapeutic aspects of familial hypercholesterolemia
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Low-density lipoprotein receptor--its structure, function, and mutations
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Regulation of the interleukin-1 receptor antagonist in THP-1 cells by ligands of the peroxisome proliferator-activated receptor gamma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Effects of pioglitazone and rosiglitazone on blood lipid levels and glycemic control in patients with type 2 diabetes mellitus: a retrospective review of randomly selected medical records
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.
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PubMed Central
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29 September 2017
Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice.
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PubMed Central
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29 September 2017
Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL.
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PubMed Central
reference URL
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29 September 2017
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Pioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: a randomized, placebo-controlled study. The Pioglitazone 027 Study Group
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PubMed Central
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29 September 2017
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Reduction of isoprostanes and regression of advanced atherosclerosis by apolipoprotein E.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
29 September 2017
Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
29 September 2017
Anti-inflammatory properties of a platelet-activating factor acetylhydrolase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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29 September 2017
Peroxisome proliferator-activated receptor-gamma activation with pioglitazone improves endothelium-dependent dilation in nondiabetic patients with major cardiovascular risk factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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2 June 2018
Connective tissue growth factor. Friend or foe?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
2 June 2018
Pioglitazone attenuates neointimal thickening via suppression of the early inflammatory response in a porcine coronary after stenting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Administration of pioglitazone in low-density lipoprotein receptor-deficient mice inhibits lesion progression and matrix metalloproteinase expression in advanced atherosclerotic plaques.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Pioglitazone inhibits in-stent restenosis in atherosclerotic rabbits by targeting transforming growth factor-beta and MCP-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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27 November 2018
Effects of pioglitazone on lipoproteins, inflammatory markers, and adipokines in nondiabetic patients with metabolic syndrome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Rosiglitazone attenuates atherosclerosis in a model of insulin insufficiency independent of its metabolic effects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Effect of pioglitazone on carotid intima-media thickness and arterial stiffness in type 2 diabetic nephropathy patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Pioglitazone reduces monocyte adhesion to vascular endothelium under flow by modulating RhoA GTPase and focal adhesion kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
A randomized, double-blind, placebo-controlled, clinical trial of the effects of pioglitazone on glycemic control and dyslipidemia in oral antihyperglycemic medication-naive patients with type 2 diabetes mellitus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Rosiglitazone (PPARgamma-agonist) attenuates atherogenesis with no effect on hyperglycaemia in a combined diabetes-atherosclerosis mouse model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Effects of pioglitazone in nondiabetic patients with arterial hypertension: a double-blind, placebo-controlled study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Antiinflammatory and antiarteriosclerotic effects of pioglitazone
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Efficacy and safety of pioglitazone in type 2 diabetes: a randomised, placebo-controlled study in patients receiving stable insulin therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Acute regression of advanced and retardation of early aortic atheroma in immunocompetent apolipoprotein-E (apoE) deficient mice by administration of a second generation [E1(-), E3(-), polymerase(-)] adenovirus vector expressing human apoE.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
The impact of pioglitazone on glycemic control and atherogenic dyslipidemia in patients with type 2 diabetes mellitus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Pioglitazone hydrochloride in combination with sulfonylurea therapy improves glycemic control in patients with type 2 diabetes mellitus: a randomized, placebo-controlled study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
High-dose recombinant apolipoprotein A-I(milano) mobilizes tissue cholesterol and rapidly reduces plaque lipid and macrophage content in apolipoprotein e-deficient mice. Potential implications for acute plaque stabilization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Activation of retinoic X receptor and peroxisome proliferator-activated receptor-gamma inhibits nitric oxide and tumor necrosis factor-alpha production in rat Kupffer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
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27 November 2018
Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes: a 6-month randomized placebo-controlled dose-response study. The Pioglitazone 001 Study Group.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684166
retrieved
27 November 2018
Human plasma platelet-activating factor acetylhydrolase. Oxidatively fragmented phospholipids as substrates
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19435790
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Differential inhibitory effects of antidiabetic drugs on arterial smooth muscle cell proliferation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19435790
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19435790
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Anti-inflammatory effects of pioglitazone and/or simvastatin in high cardiovascular risk patients with elevated high sensitivity C-reactive protein: the PIOSTAT Study
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19435790
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pioglitazone inhibits connective tissue growth factor expression in advanced atherosclerotic plaques in low-density lipoprotein receptor-deficient mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19435790
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pioglitazone and Rosiglitazone Have Different Effects on Serum Lipoprotein Particle Concentrations and Sizes in Patients With Type 2 Diabetes and Dyslipidemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19435790
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19435790
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.2353/AJPATH.2009.080611
0 references
PMCID
2684166
0 references
PubMed ID
19435790
1 reference
stated in
PubMed
PubMed ID
19435790
retrieved
25 January 2017
ResearchGate publication ID
24421223
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