(Q28513426)

English

Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation

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scholarly article

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PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation (English)

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Casitas B-lineage lymphoma

1 reference

GOA release 2020-03-11

Hepatocyte growth factor receptor

1 reference

GOA release 2020-03-11

Michaela Medová

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Dominic Leiser

1

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Benoît Pochon

2

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Wieslawa Blank-Liss

3

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Paola Francica

4

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Yitzhak Zimmer

7

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Astrid A Glück

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Daniel M Aebersold

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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publication date

17 January 2014

1 reference

Europe PubMed Central

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5 March 2020

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

588

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

5

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

653-658

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Activating mutations for the met tyrosine kinase receptor in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Tyrosine kinase mutations in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Beyond the RING: CBL proteins as multivalent adapters

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Down-regulation of MET, the receptor for hepatocyte growth factor.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Somatic mutations lead to an oncogenic deletion of met in lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

A direct role for Met endocytosis in tumorigenesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Rab11 regulates recycling through the pericentriolar recycling endosome

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

MET signaling: novel targeted inhibition and its clinical development in lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Targeting c-Met as a promising strategy for the treatment of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Targeting MET in cancer: rationale and progress

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Development of c-MET pathway inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Differential inhibition sensitivities of MET mutants to the small molecule inhibitor SU11274.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

EMD 1214063 and EMD 1204831 constitute a new class of potent and highly selective c-Met inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

MET: a promising anticancer therapeutic target

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Coupling of mutated Met variants to DNA repair via Abl and Rad51.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

The Molecular Crosstalk between the MET Receptor Tyrosine Kinase and the DNA Damage Response-Biological and Clinical Aspects

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.12.025

21 January 2018

Identifiers

10.1016/J.FEBSLET.2013.12.025

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

release_aasqogcvxrgg3kdecfvzt2tqny

1 reference

https://api.fatcat.wiki/v0/release/aasqogcvxrgg3kdecfvzt2tqny

24 November 2022

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PubMed publication ID

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24440350%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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