(Q28534977)

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Improvement of pharmacokinetics behavior of apocynin by nitrone derivatization: comparative pharmacokinetics of nitrone-apocynin and its parent apocynin in rats

scientific article (publication date: 2013)

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scholarly article

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Improvement of pharmacokinetics behavior of apocynin by nitrone derivatization: comparative pharmacokinetics of nitrone-apocynin and its parent apocynin in rats (English)

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pharmacokinetics

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based on heuristic

inferred from title

author name string

Kaiyu Wang

1

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Linlin Li

2

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Yan Song

3

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Xiaocui Ye

4

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Shaolian Fu

5

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Jie Jiang

6

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Sha Li

7

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language of work or name

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publication date

2013

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8

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7

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e70189

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copyright license

Creative Commons Attribution 4.0 International

30 July 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

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Apocynin reduces reactive oxygen species concentrations in exhaled breath condensate in asthmatics

1 reference

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19 March 2017

Synthesis and biological evaluations of novel apocynin analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3728092

29 September 2017

Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans

1 reference

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29 September 2017

NADPH oxidase inhibition improves neurological outcomes in surgically-induced brain injury.

1 reference

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29 September 2017

Tolerability and pharmacokinetics of the nitrone NXY-059 in patients with acute stroke

1 reference

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29 September 2017

Apocynin improves outcome in experimental stroke with a narrow dose range

1 reference

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2 June 2018

Bioavailability of apocynin through its conversion to glycoconjugate but not to diapocynin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3728092

2 June 2018

Activation of NADPH oxidase during progression of cardiac hypertrophy to failure

1 reference

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21 January 2018

Effect of Apocynin, an inhibitor of NADPH oxidase, in the inflammatory process induced by an experimental model of spinal cord injury.

1 reference

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21 January 2018

Oral administration of the NADPH-oxidase inhibitor apocynin partially restores diminished cartilage proteoglycan synthesis and reduces inflammation in mice

1 reference

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21 January 2018

Effect of apocynin on ozone-induced airway hyperresponsiveness to methacholine in asthmatics

1 reference

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21 January 2018

Effect of NADPH oxidase inhibition on cardiopulmonary bypass-induced lung injury

1 reference

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21 January 2018

Effect of the NADPH oxidase inhibitor apocynin on septic lung injury in guinea pigs.

1 reference

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21 January 2018

Pharmacokinetics and metabolism of the reactive oxygen scavenger alpha-phenyl-N-tert-butylnitrone in the male Sprague-Dawley rat.

1 reference

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21 January 2018

Protective effects of apocynin on "two-hit" injury induced by hemorrhagic shock and lipopolysaccharide

1 reference

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27 November 2018

Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion lung injury.

1 reference

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27 November 2018

Apocynin, a plant-derived, cartilage-saving drug, might be useful in the treatment of rheumatoid arthritis

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol

1 reference

https://pubmed.ncbi.nlm.nih.gov/23936162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apocynin improves the efficacy of secretory leukocyte protease inhibitor in experimental emphysema

1 reference

https://pubmed.ncbi.nlm.nih.gov/23936162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The oxidation of apocynin catalyzed by myeloperoxidase: proposal for NADPH oxidase inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23936162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic study of a novel stroke therapeutic, 2-[[(1,1-dimethylethyl)oxidoimino]methyl]-3,5,6-trimethylpyrazine, by a simple HPLC-UV method in rats

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0070189

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2013PLoSO...870189W

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