(Q36909306)

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Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans

scientific article published on August 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

17 August 2017

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Europe PubMed Central

Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

bioavailability

1 reference

based on heuristic

inferred from title

author name string

Susan Hurst

1

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

Cho-Ming Loi

2

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

Joanne Brodfuehrer

3

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

Ayman El-Kattan

4

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Europe PubMed Central

PubMed publication ID

17 August 2017

language of work or name

0 references

publication date

1 August 2007

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

Expert Opinion on Drug Metabolism & Toxicology

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Europe PubMed Central

PubMed publication ID

17 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

469-489

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

The road map to oral bioavailability: an industrial perspective

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Anatomical and physiological parameters affecting gastrointestinal absorption in humans and rats

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Effect of 'unstirred' water layer in the intestine on the rate and extent of absorption after oral administration.

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Stress effects on gastrointestinal transit in the rat.

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21 January 2018

Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH.

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21 January 2018

Role of intestinal bacteria in nutrient metabolism

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Intestinal cholesterol metabolism

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Metabolism of isoflavones and lignans by the gut microflora: a study in germ-free and human flora associated rats

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In vivo and in vitro models of the human colonic flora

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The lymph lipid precursor pool is a key determinant of intestinal lymphatic drug transport.

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Bile increases intestinal lymphatic drug transport in the fasted rat.

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Animal models for the study of intestinal lymphatic drug transport

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Does fluid flow across the intestinal mucosa affect quantitative oral drug absorption? Is it time for a reevaluation?

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Paracellular drug transport across intestinal epithelia: influence of charge and induced water flux.

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Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-peptides

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Physicochemical profiling in drug research: a brief survey of the state-of-the-art of experimental techniques

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Drug-like properties and the causes of poor solubility and poor permeability

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Intestinal drug transporters: in vivo function and clinical importance.

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Drug delivery to the small intestine

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Physicochemical descriptors in property-based drug design

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Species-dependent and site-specific intestinal metabolism of ester prodrugs

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Identifiers

10.1517/17425255.3.4.469

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 August 2017

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