(Q59285758)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11000545%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

Species-dependent and site-specific intestinal metabolism of ester prodrugs (English)

1 reference

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31 October 2019

7

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31 October 2019

author name string

J Van Gelder

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11000545%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

M Shafiee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11000545%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

E De Clercq

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11000545%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

F Penninckx

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11000545%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

G Van den Mooter

5

1 reference

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31 October 2019

R Kinget

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11000545%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

language of work or name

English

0 references

publication date

1 September 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11000545%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Pharmaceutics

31 October 2019

published in

1 reference

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31 October 2019

volume

205

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31 October 2019

issue

1-2

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31 October 2019

page(s)

93-100

1 reference

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Transport, uptake, and metabolism of the bis(pivaloyloxymethyl)-ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine in an in vitro cell culture system of the intestinal mucosa (Caco-2)

31 October 2019

cites work

1 reference

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7 January 2021

Drug absorption studies of prodrug esters using the Caco-2 model: evaluation of ester hydrolysis and transepithelial transport

1 reference

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7 January 2021

Mechanism-based inactivation of human cytochrome P450 3A4 by grapefruit juice and red wine

1 reference

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7 January 2021

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

Hydrolysis of ester-type drugs by the purified esterase from human intestinal mucosa

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

Comparative study of human intestinal and hepatic esterases as related to enzymatic properties and hydrolizing activity for ester-type drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

Segmental differences in drug permeability, esterase activity and ketone reductase activity in the albino rabbit intestine.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

Glycolamide Esters as Biolabile Prodrugs of Carboxylic Acid Agents: Synthesis, Stability, Bioconversion, and Physicochemical Properties

1 reference

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7 January 2021

Metabolism and pharmacokinetics of novel oral prodrugs of 9-[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) in dogs

1 reference

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7 January 2021

Rationale for Design of Biologically Reversible Drug Derivatives: Prodrugs

1 reference

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7 January 2021

Prevention of murine AIDS development by (R)-9-(2-phosphonylmethoxypropyl)adenine

1 reference

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7 January 2021

Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine

1 reference

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7 January 2021

Membrane transport of drugs in different regions of the intestinal tract of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

Inhibition of intestinal metabolism of the antiviral ester prodrug bis(POC)-PMPA by nature-identical fruit extracts as a strategy to enhance its oral absorption: an in vitro study

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

Esterases: Problems of identification and classification

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

Species differences in stereoselective hydrolase activity in intestinal mucosa

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

Species differences in the disposition of propranolol prodrugs derived from hydrolase activity in intestinal mucosa.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2800%2900507-X

7 January 2021

10.1016/S0378-5173(00)00507-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11000545%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference