(Q42689012)

4 November 2017

title

In silico prediction of ADME and pharmacokinetics. Report of an expert meeting organised by COST B15. (English)

1 reference

4 November 2017

1 reference

1 reference

5

Olavi Pelkonen

1 reference

4 November 2017

2

Ursula Gundert-Remy

1 reference

4 November 2017

Alan Boobis

1

1 reference

4 November 2017

Pierre Kremers

series ordinal

3

1 reference

4 November 2017

Panos Macheras

series ordinal

4

1 reference

4 November 2017

language of work or name

English

0 references

publication date

1 December 2002

1 reference

European Journal of Pharmaceutical Sciences

4 November 2017

published in

1 reference

4 November 2017

volume

17

1 reference

4 November 2017

issue

4-5

1 reference

4 November 2017

page(s)

183-193

1 reference

COST B15: modelling in drug development.

4 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Predicting the impact of physiological and biochemical processes on oral drug bioavailability

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Experimental and computational screening models for prediction of aqueous drug solubility

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Mode-of-action-based dosimeters for interspecies extrapolation of vinyl acetate inhalation risk

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Absorption potential and its variants.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Absorption potential: estimating the fraction absorbed for orally administered compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Application of in silico approaches to predicting drug--drug interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Progress in predicting human ADME parameters in silico

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Theoretical Model Studies of Drug Absorption and Transport in the GI Tract III

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

ADMET--turning chemicals into drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Computational models for cytochrome P450: a predictive electronic model for aromatic oxidation and hydrogen atom abstraction

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

A Bayesian analysis of the influence of GSTT1 polymorphism on the cancer risk estimate for dichloromethane.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

A heterogeneous tube model of intestinal drug absorption based on probabilistic concepts

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Heterogeneous tube model for the study of small intestinal transit flow

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Drugs as P-glycoprotein substrates, inhibitors, and inducers

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Role of drug metabolism in drug discovery and development

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Toward a quantitative approach for the prediction of the fraction of dose absorbed using the absorption potential concept

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Development of predictive pharmacokinetic simulation models for drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Estimating the fraction dose absorbed from suspensions of poorly soluble compounds in humans: a mathematical model.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

A whole-body physiologically based pharmacokinetic model incorporating dispersion concepts: short and long time characteristics.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

A priori prediction of tissue:plasma partition coefficients of drugs to facilitate the use of physiologically-based pharmacokinetic models in drug discovery.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Prediction of adipose tissue: plasma partition coefficients for structurally unrelated drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985)

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Predicting fraction dose absorbed in humans using a macroscopic mass balance approach

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Experimental and computational screening models for the prediction of intestinal drug absorption

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Theoretical Model Studies of Drug Absorption and Transport in the Gastrointestinal Tract I

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Theoretical Model Studies of Drug Absorption and Transport in the Gastrointestinal Tract II

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Role of the development scientist in compound lead selection and optimization

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Prediction of human intestinal absorption of drug compounds from molecular structure.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

A compartmental absorption and transit model for estimating oral drug absorption.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure-activity relationship (QSAR) with the Abraham descriptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900185-9

7 January 2021

10.1016/S0928-0987(02)00185-9

Identifiers

DOI

1 reference

4 November 2017

1 reference