(Q36535786)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16841194%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

review article

1 reference

title

Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16841194%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

Christopher P. Landowski

5

1 reference

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27 December 2019

Ho-chul Shin

6

1 reference

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27 December 2019

11

Duxin Sun

1 reference

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27 December 2019

9

Gordon L Amidon

1 reference

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27 December 2019

1

Xianhua Cao

1 reference

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27 December 2019

author name string

Seth T Gibbs

2

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27 December 2019

Lanyan Fang

3

1 reference

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27 December 2019

Heather A Miller

4

1 reference

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27 December 2019

Hans Lennernas

7

1 reference

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27 December 2019

Yanqiang Zhong

8

1 reference

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27 December 2019

Lawrence X Yu

10

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27 December 2019

publication date

1 August 2006

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27 December 2019

published in

Pharmaceutical Research

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27 December 2019

volume

23

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27 December 2019

page(s)

1675-1686

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27 December 2019

issue

8

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Pharmacokinetics of methyldopa in man

27 December 2019

cites work

1 reference

12 December 2020

Immuno-localization of H+/peptide cotransporter in rat digestive tract

1 reference

12 December 2020

The validation of the intestinal permeability approach to predict oral fraction of dose absorbed in humans and rats

1 reference

12 December 2020

Chronic nifedipine dosing enhances cephalexin bioavailability and intestinal absorption in conscious rats.

1 reference

12 December 2020

CYP3A gene expression in human gut epithelium

1 reference

12 December 2020

Isosorbide 5-mononitrate kinetics

1 reference

12 December 2020

Predicting fraction dose absorbed in humans using a macroscopic mass balance approach

1 reference

12 December 2020

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

1 reference

12 December 2020

Comparison of oral absorption and bioavailablity of drugs between monkey and human

1 reference

12 December 2020

Bioavailability of codeine preparations in the rat

1 reference

12 December 2020

The pharmacokinetics of lisuride hydrogen maleate in rat, rabbit and rhesus monkey

1 reference

12 December 2020

The metabolism and kinetics of doxazosin in man, mouse, rat and dog.

1 reference

12 December 2020

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats

1 reference

12 December 2020

Bioavailability of indomethacin calcium and magnesium, and effect of the salts on drug metabolizing enzyme activities in rats

1 reference

12 December 2020

Evaluation of rat intestinal absorption data and correlation with human intestinal absorption

1 reference

12 December 2020

Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach

1 reference

12 December 2020

Comparative pharmacodynamics and pharmacokinetics of cimetidine and ranitidine

1 reference

12 December 2020

Characterization of human small intestinal cytochromes P-450.

1 reference

12 December 2020

Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs

1 reference

12 December 2020

Expression and localization of the multidrug resistance-associated protein 3 in rat small and large intestine.

1 reference

12 December 2020

A possibility to predict the absorbability of poorly water-soluble drugs in humans based on rat intestinal permeability assessed by an in vitro chamber method

1 reference

12 December 2020

Pharmacokinetics of mepindolol sulfate in the rat, dog, and rhesus monkey. Studies on species differences

1 reference

12 December 2020

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

1 reference

12 December 2020

In vitro testing of drug absorption for drug 'developability' assessment: forming an interface between in vitro preclinical data and clinical outcome

1 reference

12 December 2020

Mapping of multidrug resistance gene 1 and multidrug resistance-associated protein isoform 1 to 5 mRNA expression along the human intestinal tract

1 reference

12 December 2020

Human intestinal permeability of piroxicam, propranolol, phenylalanine, and PEG 400 determined by jejunal perfusion

1 reference

12 December 2020

Acyclovir prodrug for the intestinal di/tri-peptide transporter PEPT1: comparison of in vivo bioavailability in rats and transport in Caco-2 cells.

1 reference

12 December 2020

Clinical pharmacokinetics of ketoprofen and its enantiomers

1 reference

12 December 2020

Jejunal permeability: a comparison between the ussing chamber technique and the single-pass perfusion in humans

1 reference

12 December 2020

Comparison of the permeability characteristics of a human colonic epithelial (Caco-2) cell line to colon of rabbit, monkey, and dog intestine and human drug absorption

1 reference

12 December 2020

Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas.

1 reference

12 December 2020

Expression of genes encoding for drug metabolising cytochrome P450 enzymes and P-glycoprotein in the rat small intestine; comparison to the liver

1 reference

12 December 2020

Distribution of glucuronidation capacity (1-naphthol and morphine) along the rat intestine

1 reference

12 December 2020

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

1 reference

12 December 2020

Clinical Pharmacokinetics of N-acetylprocainamide

1 reference

12 December 2020

The influence of net water absorption on the permeability of antipyrine and levodopa in the human jejunum

1 reference

12 December 2020

Passive and carrier-mediated intestinal absorption components of two angiotensin converting enzyme (ACE) inhibitor prodrugs in rats: enalapril and fosinopril

1 reference

12 December 2020

Expression profiles of drug-metabolizing enzyme CYP3A and drug efflux transporter multidrug resistance 1 subfamily mRNAS in small intestine

1 reference

12 December 2020

Jejunal absorption and metabolism of R/S-verapamil in humans

1 reference

12 December 2020

Jejunal permeability in humans in vivo and rats in situ: investigation of molecular size selectivity and solvent drag.

1 reference

12 December 2020

Buccal and oral bioavailability of nalbuphine in rats

1 reference

12 December 2020

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues

1 reference

12 December 2020

ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

1 reference

12 December 2020

The oligopeptide transporter (Pept-1) in human intestine: biology and function

1 reference

12 December 2020

Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.

1 reference

12 December 2020

First-pass elimination. Basic concepts and clinical consequences

1 reference

12 December 2020

Ingestion of chilli pepper (Capsicum annuum) reduces salicylate bioavailability after oral asprin administration in the rat

1 reference

12 December 2020

Bioavailability study of furosemide prodrugs in rats

1 reference

12 December 2020

The effect of ketoconazole on the jejunal permeability and CYP3A metabolism of (R/S)-verapamil in humans

1 reference

12 December 2020

Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation

1 reference

12 December 2020

Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents

1 reference

12 December 2020

Gene Expression in the Human Intestine and Correlation with Oral Valacyclovir Pharmacokinetic Parameters

1 reference

12 December 2020

Verapamil. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension

1 reference

12 December 2020

cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)

1 reference

12 December 2020

Pharmacokinetics of tetrabenazine and its major metabolite in man and rat. Bioavailability and dose dependency studies.

1 reference

12 December 2020

Interaction of tri-O-methyl-beta-cyclodextrin with drugs. II. Enhanced bioavailability of ketoprofen in rats when administered with tri-O-methyl-beta-cyclodextrin

1 reference

12 December 2020

Absorption and bioavailability of captopril in mice and rats after administration by gavage and in the diet

1 reference

12 December 2020

STUDIES ON THE ABSORPTION, METABOLISM AND EXCRETION OF METHYLDOPA AND OTHER CATECHOLS AND THEIR INFLUENCE ON AMINO ACID TRANSPORT IN RATS

1 reference

12 December 2020

Intestinal absorption of amino acid derivatives: importance of the free alpha-amino group

1 reference

12 December 2020

Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.

1 reference

12 December 2020

Tacrolimus is a class II low-solubility high-permeability drug: the effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats

1 reference

12 December 2020

Human intestinal permeability

1 reference

12 December 2020

Pharmacokinetics of captopril in healthy subjects and in patients with cardiovascular diseases

1 reference

12 December 2020

The lack of effect of induced net fluid absorption on the in vivo permeability of terbutaline in the human jejunum

1 reference

12 December 2020

Rat jejunal permeability and metabolism of mu-selective tetrapeptides in gastrointestinal fluids from humans and rats

1 reference

12 December 2020

Human jejunal permeability of two polar drugs: cimetidine and ranitidine

1 reference

12 December 2020

Comparison between permeability coefficients in rat and human jejunum

1 reference

12 December 2020

Bioavailability of N-acetylprocainamide from mixed diet in rats

1 reference

12 December 2020

Is the role of the small intestine in first-pass metabolism overemphasized?

1 reference

12 December 2020

Levonorgestrel. Clinical pharmacokinetics

1 reference

12 December 2020

Glucose transporter 1 (GLUT1) expression is associated with intestinal type of gastric carcinoma

1 reference

12 December 2020

Clinical pharmacokinetics of the salicylates

1 reference

12 December 2020

Clinical pharmacokinetics of the antituberculosis drugs

1 reference

12 December 2020

Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in man

1 reference

12 December 2020

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine

1 reference

12 December 2020

The absolute bioavailability and effect of food on the pharmacokinetics of zolmitriptan in healthy volunteers

1 reference

12 December 2020

Pharmacokinetics of the enantiomers of verapamil after intravenous and oral administration of racemic verapamil in a rat model

1 reference

12 December 2020

Nonlinear bioavailability of metoclopramide in the rat: evidence for saturable first-pass metabolism.

1 reference

12 December 2020

Terminal half-lives in plasma and bioavailability of norethisterone, levonorgestrel, cyproterone acetate and gestodene in rats, beagles and rhesus monkeys

1 reference

12 December 2020

Correlation between epithelial cell permeability of cephalexin and expression of intestinal oligopeptide transporter

1 reference

12 December 2020