(Q28542566)

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Suppression of the PI3K pathway in vivo reduces cystitis-induced bladder hypertrophy and restores bladder capacity examined by magnetic resonance imaging

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scholarly article

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Suppression of the PI3K pathway in vivo reduces cystitis-induced bladder hypertrophy and restores bladder capacity examined by magnetic resonance imaging (English)

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author name string

Zhongwei Qiao

1

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Chunmei Xia

2

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Shanwei Shen

3

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Frank D Corwin

4

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Miao Liu

5

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Ruijuan Guan

6

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John R Grider

7

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Li-Ya Qiao

8

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language of work or name

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publication date

2014

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9

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12

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e114536

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copyright license

Creative Commons Attribution 4.0 International

8 December 2014

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April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

magnetic resonance imaging

1 reference

based on heuristic

inferred from title

Upregulation of macrophage migration inhibitory factor (MIF) and CD74, receptor for MIF, in rat bladder during persistent cyclophosphamide-induced inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

19 March 2017

AKT/PKB signaling: navigating downstream

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

19 March 2017

Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

19 March 2017

Akt signaling: linking membrane events to life and death decisions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

19 March 2017

Cyclophosphamide cystitis—Identification of acrolein as the causative agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

19 March 2017

In vivo magnetic resonance imaging of type I collagen scaffold in rat: improving visualization of bladder and subcutaneous implants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

In vivo regulation of brain-derived neurotrophic factor in dorsal root ganglia is mediated by nerve growth factor-triggered Akt activation during cystitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Treatment with a cannabinoid receptor 2 agonist decreases severity of established cystitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Endogenous PI3K/Akt and NMDAR act independently in the regulation of CREB activity in lumbosacral spinal cord in cystitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Expression and function of transforming growth factor-β isoforms and cognate receptors in the rat urinary bladder following cyclophosphamide-induced cystitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

MCP-1-induced histamine release from mast cells is associated with development of interstitial cystitis/bladder pain syndrome in rat models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Connective tissue and its growth factor CTGF distinguish the morphometric and molecular remodeling of the bladder in a model of neurogenic bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Regulation of IGF-1 but not TGF-β1 by NGF in the smooth muscle of the inflamed urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

The PI3K/Akt pathway mediates the expression of type I collagen induced by TGF-β2 in human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Role of inflammation in bladder function and interstitial cystitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Role for pAKT in rat urinary bladder with cyclophosphamide (CYP)-induced cystitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Increased expression of interleukin-6 family members and receptors in urinary bladder with cyclophosphamide-induced bladder inflammation in female rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Expression and function of CXCL12/CXCR4 in rat urinary bladder with cyclophosphamide-induced cystitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Endogenous nerve growth factor regulates collagen expression and bladder hypertrophy through Akt and MAPK pathways during cystitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Alteration of the PKC-mediated signaling pathway for smooth muscle contraction in obstruction-induced hypertrophy of the urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Cyclophosphamide-induced cystitis increases bladder CXCR4 expression and CXCR4-macrophage migration inhibitory factor association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Effects of intravesical instillation of resiniferatoxin on bladder function and nociceptive behavior in freely moving, conscious rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Acute acrolein-induced cystitis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

From the archives of the AFIP: Inflammatory and nonneoplastic bladder masses: radiologic-pathologic correlation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

The survival kinases Akt and Pim as potential pharmacological targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Magnetic resonance imaging of the pelvis: prostate and urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Hypertrophy of visceral smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Magnetic resonance imaging of the prostate and bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

29 September 2017

Involvement of interleukin-6-regulated nitric oxide synthase in hemorrhagic cystitis and impaired bladder contractions in young rats induced by acrolein, a urinary metabolite of cyclophosphamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

3 June 2018

Akt blockade downregulates collagen and upregulates MMP1 in human dermal fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

3 June 2018

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

3 June 2018

Urinary bladder MR imaging. Part I. Normal and benign conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259345

3 June 2018

Bladder outlet obstruction: progression from inflammation to fibrosis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Changes in urinary bladder cytokine mRNA and protein after cyclophosphamide-induced cystitis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Alterations in neuropeptide expression in lumbosacral bladder pathways following chronic cystitis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Alteration of muscarinic and purinergic receptors in urinary bladder of rats with cyclophosphamide-induced interstitial cystitis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Therapeutic effects of the putative P2X3/P2X2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Inhibition of collagen deposit in obstructed rat bladder outlet by transplantation of superparamagnetic iron oxide-labeled human mesenchymal stem cells as monitored by molecular magnetic resonance imaging (MRI).

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Dynamic contrast-enhanced magnetic resonance imaging of abdominal solid organ and major vessel: comparison of enhancement effect between Gd-EOB-DTPA and Gd-DTPA.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

High-resolution magnetic resonance imaging tracks changes in organ and tissue mass in obese and aging rats.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Pelvic floor failure: MR imaging evaluation of anatomic and functional abnormalities

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Bladder wall thickness mapping for magnetic resonance cystography

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Suppression of type I collagen expression by miR-29b via PI3K, Akt, and Sp1 pathway in human Tenon's fibroblasts.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0114536

21 January 2018

Novel approach to segment the inner and outer boundaries of the bladder wall in T2-weighted magnetic resonance images

1 reference

https://pubmed.ncbi.nlm.nih.gov/25486122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improvement by phytotherapeutic agent of detrusor overactivity, down-regulation of pharmacological receptors and urinary cytokines in rats with cyclophosphamide induced cystitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25486122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of mouse bladder inflammatory response to E. coli lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/25486122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine receptor antagonism suppresses functional and histological inflammatory changes in the rat urinary bladder

1 reference

https://pubmed.ncbi.nlm.nih.gov/25486122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25486122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of bladder outlet obstruction treatment on ultrasound-determined bladder wall thickness

1 reference

https://pubmed.ncbi.nlm.nih.gov/25486122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary bladder MR imaging. Part II. Neoplasm

1 reference

https://pubmed.ncbi.nlm.nih.gov/25486122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interstitial Cystitis in Men

1 reference

https://pubmed.ncbi.nlm.nih.gov/25486122

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0114536

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2014PLoSO...9k4536Q

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