(Q28542945)

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Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

type 2 diabetes

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Dioscorea bulbifera

object named as

Dioscorea bulbifera

1 reference

based on heuristic

inferred from title

1

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16 February 2020

4

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16 February 2020

6

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16 February 2020

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Vaishali S Shinde

11

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16 February 2020

Dilip D. Dhavale

12

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16 February 2020

author name string

Piyush More

2

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16 February 2020

Abhishek Derle

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Pramod Markad

5

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16 February 2020

Navanath Kumbhar

8

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16 February 2020

Mahemud L Shaikh

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Boppana Ramanamurthy

10

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16 February 2020

Balu A Chopade

13

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16 February 2020

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12 September 2014

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16 February 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

9

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

e106039

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

copyright license

Creative Commons Attribution 4.0 International

12 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Phytochemical analysis and free radical scavenging activity of medicinal plants Gnidia glauca and Dioscorea bulbifera

1 reference

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Chlorogenic acid and rutin play a major role in the in vivo anti-diabetic activity of Morus alba leaf extract on type II diabetic rats

1 reference

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X-ray Crystallographic Analyses of Pig Pancreatic α-Amylase with Limit Dextrin, Oligosaccharide, and α-Cyclodextrin ,

1 reference

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AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

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19 March 2017

Crystal structure of GH13 alpha-glucosidase GSJ from one of the deepest sea bacteria

1 reference

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RM1: a reparameterization of AM1 for H, C, N, O, P, S, F, Cl, Br, and I

1 reference

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19 March 2017

Intestinal disaccharidases and some renal enzymes in streptozotocin-induced diabetic rats fed sapogenin extract from bitter yam (Dioscorea polygonoides)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

19 March 2017

Enzyme-catalyzed condensation reaction in a mammalian alpha-amylase. High-resolution structural analysis of an enzyme-inhibitor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

19 March 2017

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

19 March 2017

The crystal structure of porcine pancreatic alpha-amylase in complex with the microbial inhibitor Tendamistat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

19 March 2017

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

19 March 2017

Effect of diosgenin on lipid metabolism in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

19 March 2017

IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030

1 reference

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7 April 2017

Curcumin-Loaded, Self-Assembled Aloevera Template for Superior Antioxidant Activity and Trans-Membrane Drug Release

1 reference

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29 September 2017

A simple, efficient synthesis of 2-aryl benzimidazoles using silica supported periodic Acid catalyst and evaluation of anticancer activity

1 reference

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29 September 2017

Antidiabetic and antioxidant effects and phytochemicals of mulberry fruit (Morus alba L.) polyphenol enhanced extract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Synthesis of silver nanoparticles using Dioscorea bulbifera tuber extract and evaluation of its synergistic potential in combination with antimicrobial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Antidiabetic Activity of Gnidia glauca and Dioscorea bulbifera: Potent Amylase and Glucosidase Inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Potent α-amylase inhibitory activity of Indian Ayurvedic medicinal plants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Design and synthesis of harzialactone analogues: promising anticancer agents.

1 reference

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29 September 2017

Evaluation of Traditional Indian Antidiabetic Medicinal Plants for Human Pancreatic Amylase Inhibitory Effect In Vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Analgesic and Anti-Inflammatory Properties of Extracts from the Bulbils of Dioscorea bulbifera L. var sativa (Dioscoreaceae) in Mice and Rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Structure-based design of a thiazolidinedione which targets the mitochondrial protein mitoNEET.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Depression and advanced complications of diabetes: a prospective cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Human salivary alpha-amylase Trp58 situated at subsite -2 is critical for enzyme activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

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New drug targets for type 2 diabetes and the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

29 September 2017

Structure of a pancreatic alpha-amylase bound to a substrate analogue at 2.03 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162539

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Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues

1 reference

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Antidiabetic Indian plants: a good source of potent amylase inhibitors

1 reference

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1 reference

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Hypoglycemic effects of steroidal sapogenins isolated from Jamaican bitter yam, Dioscorea polygonoides

1 reference

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Isolation and characterization of an intermediate steroid metabolite in diosgenin biosynthesis in suspension cultures of Dioscorea deltoidea cells

1 reference

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Synthesis, crystal structure and antidiabetic activity of substituted (E)-3-(Benzo [d]thiazol-2-ylamino) phenylprop-2-en-1-one.

1 reference

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1 reference

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13C cross-polarization MAS NMR study of some steroidal sapogenins

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0106039

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Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of yam (Dioscorea spp.), on high-cholesterol fed rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0106039

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Diosgenin-induced biliary cholesterol secretion in mice requires Abcg8.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0106039

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Diosgenin targets Akt-mediated prosurvival signaling in human breast cancer cells

1 reference

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Acute administration of diosgenin or dioscorea improves hyperglycemia with increases muscular steroidogenesis in STZ-induced type 1 diabetic rats.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0106039

21 January 2018

Determining the binding affinities of phenolic compounds to proteins by quenching of the intrinsic tryptophan fluorescence.

1 reference

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Chemical modification of lysine residues in Bacillus alpha-amylases: effect on activity and stability

1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/25216353

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based on heuristic

inferred from PubMed ID database lookup

In vivo and in vitro studies of hypocholesterolemic effects of diosgenin in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25216353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/25216353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0106039

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

2014PLoSO...9j6039G

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216353%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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