(Q28544844)

English

Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans

scientific article (publication date: November 2014)

In more languages

Statements

scholarly article

0 references

Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans (English)

0 references

0 references

Florian Holsboer

15

object named as

Florian Holsboer

0 references

17

object named as

Manfred Uhr

0 references

18

object named as

Marcus Ising

0 references

Georgia Balsevich

object named as

Georgia Balsevich

11

0 references

object named as

Jakob Hartmann

2

0 references

object named as

Matthias Eder

16

0 references

object named as

Stefan Kloiber

13

0 references

Mathias V Schmidt

object named as

Mathias V Schmidt

19

0 references

object named as

Theo Rein

20

0 references

Jan M. Deussing

object named as

Jan M Deussing

12

0 references

5

object named as

Kathrin Hafner

0 references

Nils Christian Gassen

1

object named as

Nils C Gassen

0 references

Jürgen Zschocke

3

object named as

Jürgen Zschocke

0 references

Andreas Zellner

6

object named as

Andreas Zellner

0 references

14

object named as

Susanne Lucae

0 references

author name string

Jens Stepan

4

0 references

Thomas Kirmeier

7

0 references

Lorenz Kollmannsberger

8

0 references

Klaus V Wagner

9

0 references

Nina Dedic

10

0 references

language of work or name

0 references

publication date

November 2014

0 references

0 references

11

0 references

11

0 references

e1001755

0 references

copyright license

Creative Commons Attribution 4.0 International

11 November 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Treatment of bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

Trehalose induced antidepressant-like effects and autophagy enhancement in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

Enhancement of dorsal hippocampal activity by knockdown of HCN1 channels leads to anxiolytic- and antidepressant-like behaviors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

Snapin-regulated late endosomal transport is critical for efficient autophagy-lysosomal function in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

Autophagy in the Pathogenesis of Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

AKT/PKB signaling: navigating downstream

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

New approaches to antidepressant drug discovery: beyond monoamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

19 March 2017

Autophagy: renovation of cells and tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

7 April 2017

Network medicine: a network-based approach to human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

7 April 2017

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

7 April 2017

Animal models of neuropsychiatric disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

7 April 2017

mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

7 April 2017

Dynamics and diversity in autophagy mechanisms: lessons from yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

7 April 2017

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

7 April 2017

Stress and the brain: from adaptation to disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

7 April 2017

Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Differences in FKBP51 regulation following chronic social defeat stress correlate with individual stress sensitivity: influence of paroxetine treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Accumulation of an antidepressant in vesiculogenic membranes of yeast cells triggers autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Control of autophagy as a therapy for neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

The tricyclic antidepressant imipramine induces autophagic cell death in U-87MG glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

A standardized protocol for repeated social defeat stress in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Antidepressant drugs diversely affect autophagy pathways in astrocytes and neurons--dissociation from cholesterol homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Forebrain CRHR1 deficiency attenuates chronic stress-induced cognitive deficits and dendritic remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

The WHO World Mental Health (WMH) Surveys.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

A small molecule inhibits Akt through direct binding to Akt and preventing Akt membrane translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Pharmacogenetics studies in STAR*D: strengths, limitations, and results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Antidepressive-like effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of affective disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Genetic dissection of neural circuits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Inhibitory effect of imipramine on the human corticotropin-releasing-hormone gene promoter activity operates through a PI3-K/AKT mediated pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

The corticosteroid receptor hypothesis of depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

CNS glia are targets for GDNF and neurturin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

29 September 2017

Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

3 June 2018

FK506 binding protein 5 shapes stress responsiveness: modulation of neuroendocrine reactivity and coping behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

3 June 2018

Neuropsin cleaves EphB2 in the amygdala to control anxiety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

3 June 2018

Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

3 June 2018

Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

3 June 2018

Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227651

3 June 2018

The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Antidepressant desipramine leads to C6 glioma cell autophagy: implication for the adjuvant therapy of cancer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Pituitary glucocorticoid receptor deletion reduces vulnerability to chronic stress.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

The use of behavioral test batteries: effects of training history.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

A refined method for sequential blood sampling by tail incision in rats.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Antidepressant like effect of selective serotonin reuptake inhibitors involve modulation of imidazoline receptors by agmatine.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Long-term anxiolytic and antidepressant-like behavioural effects of tiagabine, a selective GABA transporter-1 (GAT-1) inhibitor, coincide with a decrease in HPA system activity in C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Selective modulation of the PKCɛ/p38MAP kinase signalling pathway for the antidepressant-like activity of amitriptyline.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Fluoxetine upregulates phosphorylated-AKT and phosphorylated-ERK1/2 proteins in neural stem cells: evidence for a crosstalk between AKT and ERK1/2 pathways

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Overexpression of the FK506-binding immunophilin FKBP51 is the common cause of glucocorticoid resistance in three New World primates

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Regulation of presynaptic neurotransmission by macroautophagy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.1001755

21 January 2018

Neurotransmission: Autophagy regulates transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/25386878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of the Hamilton Rating Scale for classification of depressive disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/25386878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PMED.1001755

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28544844&oldid=1859713760"