(Q28545984)

English

Drug repurposing: a systematic approach to evaluate candidate oral neuroprotective interventions for secondary progressive multiple sclerosis

scientific article

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scholarly article

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Drug repurposing: a systematic approach to evaluate candidate oral neuroprotective interventions for secondary progressive multiple sclerosis (English)

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secondary progressive multiple sclerosis

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multiple sclerosis

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8

object named as

Sue Pavitt

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object named as

Peter Connick

2

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object named as

Kieren J Egan

5

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object named as

Emily S Sena

4

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Malcolm Macleod

object named as

Malcolm R Macleod

10

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Siddharthan Chandran

object named as

Siddharthan Chandran

11

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Hanna M Vesterinen

1

object named as

Hanna M Vesterinen

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Cadi M J Irvine

3

object named as

Cadi M J Irvine

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Jeremy Chataway

9

object named as

Jeremy Chataway

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author name string

Gary G Carmichael

6

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Afiyah Tariq

7

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language of work or name

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publication date

2015

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full work available at URL

http://eprints.whiterose.ac.uk/85847/

content deliverer

White Rose Research Online

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external data available at URL

https://doi.org/10.5061/dryad.8qd33

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10

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4

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e0117705

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copyright license

Creative Commons Attribution 4.0 International

9 April 2015

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April 2022 Public Data File from Crossref

copyright status

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Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

19 March 2017

Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

19 March 2017

Scientific value of systematic reviews: survey of editors of core clinical journals

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19 March 2017

Publication bias in reports of animal stroke studies leads to major overstatement of efficacy

1 reference

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19 March 2017

Can animal models of disease reliably inform human studies?

1 reference

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19 March 2017

Predicting new molecular targets for known drugs

1 reference

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Grading quality of evidence and strength of recommendations

1 reference

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19 March 2017

Drug target identification using side-effect similarity

1 reference

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7 April 2017

Drug repositioning: identifying and developing new uses for existing drugs

1 reference

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7 April 2017

Meta-analysis of data from animal studies: a practical guide

1 reference

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29 September 2017

Contribution of genome-wide association studies to scientific research: a pragmatic approach to evaluate their impact

1 reference

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29 September 2017

Computational drug repositioning: from data to therapeutics

1 reference

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29 September 2017

Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Predictive methods in drug repurposing: gold mine or just a bigger haystack?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Acid-sensing ion channels in pathological conditions

1 reference

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29 September 2017

Amyotrophic lateral sclerosis: drug therapy from the bench to the bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Large-scale prediction and testing of drug activity on side-effect targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Mechanisms of neurodegeneration shared between multiple sclerosis and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Critical appraisal of animal models of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Improving the translational hit of experimental treatments in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Inflammation, demyelination, and degeneration - recent insights from MS pathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Ibudilast in relapsing-remitting multiple sclerosis: a neuroprotectant?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Ibudilast: a review of its pharmacology, efficacy and safety in respiratory and neurological disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Neuroprotection in multiple sclerosis: therapeutic strategies and clinical trial design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Secondary progressive multiple sclerosis: current knowledge and future challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Target-based drug discovery: is something wrong?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

Pooling of animal experimental data reveals influence of study design and publication bias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

A double-blind controlled trial of long chain n-3 polyunsaturated fatty acids in the treatment of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

29 September 2017

The effect of fluoxetine on progression in progressive multiple sclerosis: a double-blind, randomized, placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

3 June 2018

Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

3 June 2018

Oxcarbazepine for treating paroxysmal painful symptoms in multiple sclerosis: a pilot study.

1 reference

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3 June 2018

A double-blind, randomized, controlled study of oral pirfenidone for treatment of secondary progressive multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

3 June 2018

Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0117705

21 January 2018

Drug research: plug the real brain drain.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0117705

21 January 2018

Up-regulation of 5-HT2B receptor density and receptor-mediated glycogenolysis in mouse astrocytes by long-term fluoxetine administration

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0117705

21 January 2018

Fluoxetine increases cerebral white matter NAA/Cr ratio in patients with multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0117705

21 January 2018

Effects of fluoxetine on disease activity in relapsing multiple sclerosis: a double-blind, placebo-controlled, exploratory study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0117705

21 January 2018

The Delphi List

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0117705

21 January 2018

The Delphi list: a criteria list for quality assessment of randomized clinical trials for conducting systematic reviews developed by Delphi consensus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391783

27 November 2018

Could pharma open its drug freezers?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25856304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug repurposing programmes get lift off

1 reference

https://pubmed.ncbi.nlm.nih.gov/25856304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0117705

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2015PLoSO..1017705V

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10.1371/JOURNAL.PONE.0117705

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Dimensions Publication ID

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Microsoft Academic ID

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PMC publication ID

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PubMed publication ID

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ResearchGate publication ID

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2-s2.0-84928812195

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