(Q28546576)

English

Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds

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scholarly article

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Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds (English)

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Plasmodium falciparum

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Plasmodium falciparum 3D7 hexose transporter

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10 September 2018

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object named as

Carolyn Elya

4

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Alexander G. Johnson

object named as

Alex Johnson

3

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object named as

Yuko Sato

10

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W. Armand Guiguemde

2

object named as

W Armand Guiguemde

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Scott M. Landfear

12

object named as

Scott M Landfear

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11

object named as

R Kiplin Guy

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Michele C Connelly

7

object named as

Michele Connelly

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9

object named as

Jaeki Min

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author name string

Diana Ortiz

1

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Johanna Anderson

5

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Julie Clark

6

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Lei Yang

8

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language of work or name

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publication date

2015

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10

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4

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e0123598

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copyright license

Creative Commons Attribution 4.0 International

20 April 2015

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April 2022 Public Data File from Crossref

copyright status

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The open access malaria box: a drug discovery catalyst for neglected diseases

1 reference

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19 March 2017

The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites

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Qinghaosu (Artemisinin): The Price of Success

1 reference

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The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is located in the apicoplast

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Human malaria parasites in continuous culture

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Chemical genetics of Plasmodium falciparum

1 reference

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Intraerythrocytic Plasmodium falciparum expresses a high affinity facilitative hexose transporter

1 reference

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1 reference

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1 reference

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Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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New antimalarial targets: the example of glucose transport

1 reference

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Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening.

1 reference

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Validation of the hexose transporter of Plasmodium falciparum as a novel drug target.

1 reference

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Combination therapy for malaria: mission accomplished?

1 reference

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1 reference

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Microbiology. Exploiting malaria drug resistance to our advantage.

1 reference

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Four conserved cytoplasmic sequence motifs are important for transport function of the Leishmania inositol/H(+) symporter.

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Comparison of intrinsic clearance in liver microsomes and hepatocytes from rats and humans: evaluation of free fraction and uptake in hepatocytes.

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1 reference

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based on heuristic

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Physiological parameters in laboratory animals and humans

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0123598

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2015PLoSO..1023598O

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