(Q28547020)

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Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26244849%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340) (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26244849%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Éverton de Almeida Alves Barbosa

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26244849%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Marcelo Depólo Polêto

3

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Europe PubMed Central

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20 February 2020

14

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20 February 2020

Róbson R Teixeira

16

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20 February 2020

Julio Cesar Borges

17

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20 February 2020

José Andres Yunes

18

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20 February 2020

Leandro L. Oliveira

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Raoni Pais Siqueira

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20 February 2020

Germanna Lima Righetto

4

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20 February 2020

Rafael Locatelli Salgado

6

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20 February 2020

Joana Gasperazzo Ferreira

7

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20 February 2020

Marcus Vinícius de Andrade Barros

8

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20 February 2020

Leandro Licursi de Oliveira

9

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20 February 2020

Angelo Brunelli Albertoni Laranjeira

10

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20 February 2020

Márcia Rogéria Almeida

11

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20 February 2020

Abelardo Silva Júnior

12

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20 February 2020

Juliana Lopes Rangel Fietto

13

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20 February 2020

Eduardo Basílio de Oliveira

15

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20 February 2020

Gustavo Costa Bressan

19

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20 February 2020

Thiago Vargas Seraphim

5

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20 February 2020

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5 August 2015

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20 February 2020

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20 February 2020

10

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20 February 2020

8

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20 February 2020

e0134882

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20 February 2020

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Creative Commons Attribution 4.0 International

5 August 2015

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4526641/fullTextXML

based on heuristic

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Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

Identification of a novel function of CX-4945 as a splicing regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

Phosphorylation-mediated regulation of alternative splicing in cancer

1 reference

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19 March 2017

Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition

1 reference

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19 March 2017

The kinase inhibitor SFV785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly

1 reference

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19 March 2017

Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

Serine-arginine protein kinases: a small protein kinase family with a large cellular presence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

Inhibition of hepatitis C virus replication by a specific inhibitor of serine-arginine-rich protein kinase

1 reference

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19 March 2017

The PI3K pathway as drug target in human cancer

1 reference

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19 March 2017

Targeting the PI3K signaling pathway in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

The pathobiology of splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

The spliceosome: design principles of a dynamic RNP machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

Alternative isoform regulation in human tissue transcriptomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

Serine/arginine protein-specific kinase 2 promotes leukemia cell proliferation by phosphorylating acinus and regulating cyclin A1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

1 reference

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19 March 2017

Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

SR proteins: a conserved family of pre-mRNA splicing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

19 March 2017

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

7 April 2017

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

7 April 2017

A semiempirical free energy force field with charge-based desolvation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

7 April 2017

The SR protein family of splicing factors: master regulators of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

7 April 2017

A biomolecular force field based on the free enthalpy of hydration and solvation: the GROMOS force-field parameter sets 53A5 and 53A6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

7 April 2017

Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma

1 reference

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29 September 2017

Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

29 September 2017

SRPK1 Dissimilarly Impacts on the Growth, Metastasis, Chemosensitivity and Angiogenesis of Glioma in Normoxic and Hypoxic Conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

29 September 2017

Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

29 September 2017

Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

29 September 2017

Specific inhibition of serine/arginine-rich protein kinase attenuates choroidal neovascularization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

29 September 2017

Regulation of splicing by SR proteins and SR protein-specific kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

29 September 2017

Elevated expression of the serine-arginine protein kinase 1 gene in ovarian cancer and its role in Cisplatin cytotoxicity in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

29 September 2017

Abnormal expression of the pre-mRNA splicing regulators SRSF1, SRSF2, SRPK1 and SRPK2 in non small cell lung carcinoma

1 reference

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29 September 2017

WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing

1 reference

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29 September 2017

The SRSF1 linker induces semi-conservative ESE binding by cooperating with the RRMs

1 reference

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29 September 2017

The N-terminal fragment from caspase-cleaved serine/arginine protein-specific kinase2 (SRPK2) translocates into the nucleus and promotes apoptosis

1 reference

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29 September 2017

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1 reference

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29 September 2017

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1 reference

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29 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4526641

29 September 2017

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1 reference

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29 September 2017

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29 September 2017

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1 reference

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29 September 2017

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1 reference

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29 September 2017

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1 reference

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29 September 2017

Broad specificity of SR (serine/arginine) proteins in the regulation of alternative splicing of pre-messenger RNA.

1 reference

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29 September 2017

Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones

1 reference

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3 June 2018

p210BCR/ABL-induced alteration of pre-mRNA splicing in primary human CD34+ hematopoietic progenitor cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0134882

21 January 2018

SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0134882

21 January 2018

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1 reference

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21 January 2018

General atomic and molecular electronic structure system

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0134882

21 January 2018

Novel Destabilization of Nucleotide Binding by the γ Phosphate of ATP in the Yeast SR Protein Kinase Sky1p

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0134882

21 January 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/26244849

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic, and pancreatic carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/26244849

12 December 2020

based on heuristic

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10.1371/JOURNAL.PONE.0134882

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26244849%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

2015PLoSO..1034882S

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Europe PubMed Central

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20 February 2020

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Europe PubMed Central

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20 February 2020

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