(Q24323291)

GOA release 2020-03-11

SRSF protein kinase 1

1 reference

regulation of mRNA splicing, via spliceosome

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Thomas Giannakouros

1

0 references

Eleni Nikolakaki

2

0 references

Ilias Mylonis

3

0 references

Eleni Georgatsou

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

4

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language of work or name

English

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publication date

February 2011

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published in

FEBS Journal

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volume

278

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issue

4

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page(s)

570-86

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cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

A mitotic role for a novel fission yeast protein kinase dsk1 with cell cycle stage dependent phosphorylation and localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Regulated cellular partitioning of SR protein-specific kinases in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Fission yeast mitotic regulator Dsk1 is an SR protein-specific kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Interactions between two fission yeast serine/arginine-rich proteins and their modulation by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Dsk1p kinase phosphorylates SR proteins and regulates their cellular localization in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Serine/arginine protein-specific kinase 2 promotes leukemia cell proliferation by phosphorylating acinus and regulating cyclin A1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Conservation in budding yeast of a kinase specific for SR splicing factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Phosphorylation regulates in vivo interaction and molecular targeting of serine/arginine-rich pre-mRNA splicing factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Conserved SR protein kinase functions in nuclear import and its action is counteracted by arginine methylation in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Cloning and characterization of an alternatively spliced form of SR protein kinase 1 that interacts specifically with scaffold attachment factor-B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Negative regulation of active zone assembly by a newly identified SR protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

A novel Physarum polycephalum SR protein kinase specifically phosphorylates the RS domain of the human SR protein, ASF/SF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Localization of serine kinases, SRPK1 (SFRSK1) and SRPK2 (SFRSK2), specific for the SR family of splicing factors in mouse and human chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

A computational analysis of sequence features involved in recognition of short introns

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Phosphorylation by SR kinases regulates the binding of PTB-associated splicing factor (PSF) to the pre-mRNA polypyrimidine tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

SRPK1 and LBR protein kinases show identical substrate specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Phosphorylation by LAMMER protein kinases: determination of a consensus site, identification of in vitro substrates, and implications for substrate preferences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Transportin-SR2 mediates nuclear import of phosphorylated SR proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

A proposed signaling motif for nuclear import in mRNA processing via the formation of arginine claw

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The E1circumflexE4 protein of human papillomavirus interacts with the serine-arginine-specific protein kinase SRPK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Identification of SRPK1 and SRPK2 as the major cellular protein kinases phosphorylating hepatitis B virus core protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Suppression of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Utilization of host SR protein kinases and RNA-splicing machinery during viral replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Targeting the RNA splicing machinery as a novel treatment strategy for pancreatic carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Serological identification of adult T-cell leukaemia-associated antigens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Distinct functions of SR proteins in alternative pre-mRNA splicing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The protamine family of sperm nuclear proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Unique chromatin remodeling and transcriptional regulation in spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Temporal association of protamine 1 with the inner nuclear membrane protein lamin B receptor during spermiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The SR protein family: pleiotropic functions in pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Immunoelectron microscopical distribution of histones H2B and H3 and protamines in the course of mouse spermiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Signaling to chromatin through histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The importin beta/importin 7 heterodimer is a functional nuclear import receptor for histone H1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Screening for modulators of spermine tolerance identifies Sky1, the SR protein kinase of Saccharomyces cerevisiae, as a regulator of polyamine transport and ion homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The inner nuclear membrane: simple, or very complex?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Histones H3/H4 form a tight complex with the inner nuclear membrane protein LBR and heterochromatin protein 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The inner nuclear membrane protein lamin B receptor forms distinct microdomains and links epigenetically marked chromatin to the nuclear envelope.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

RNA association or phosphorylation of the RS domain prevents aggregation of RS domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Regulation of binding of lamin B receptor to chromatin by SR protein kinase and cdc2 kinase in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Concepts in nuclear architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Perinuclear localization of chromatin facilitates transcriptional silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The A-type cyclins and the meiotic cell cycle in mammalian male germ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

ASAP, a novel protein complex involved in RNA processing and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Nuclear cyclin D1: an oncogenic driver in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The splicing factor SC35 has an active role in transcriptional elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Metabolic control through the PGC-1 family of transcription coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Clking on PGC-1alpha to inhibit gluconeogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

A serine/arginine-rich domain in the human U1 70k protein is necessary and sufficient for ASF/SF2 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Functional coexpression of serine protein kinase SRPK1 and its substrate ASF/SF2 in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

The structure of Sky1p reveals a novel mechanism for constitutive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

SR protein kinase 1 is resilient to inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Protein kinase CK2 phosphorylates and activates the SR protein-specific kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

A quantitative atlas of mitotic phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Trypanosoma cruzi TcSRPK, the first protozoan member of the SRPK family, is biochemically and functionally conserved with metazoan SR protein-specific kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

Localization of P32 protein (gC1q-R) in mitochondria and at specific extramitochondrial locations in normal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

7 January 2021

Phosphorylation of human sperm protamines HP1 and HP2: identification of phosphorylation sites

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

7 January 2021

Involvement of SR proteins in mRNA surveillance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

7 January 2021

Vertebrate protamine genes and the histone-to-protamine replacement reaction

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

7 January 2021

Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

7 January 2021

A nuclear envelope-associated kinase phosphorylates arginine-serine motifs and modulates interactions between the lamin B receptor and other nuclear proteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

7 January 2021

Mitotic phosphorylation of the lamin B receptor by a serine/arginine kinase and p34(cdc2)

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

7 January 2021

Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic, and pancreatic carcinomas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07987.X

7 January 2021