(Q46634476)

23 December 2017

title

Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome (English)

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23 December 2017

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Reinhard Georg Lührmann

6

object named as

Reinhard Lührmann

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23 December 2017

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Henning Urlaub

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23 December 2017

author name string

Rebecca Mathew

1

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23 December 2017

Klaus Hartmuth

2

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23 December 2017

Sina Möhlmann

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23 December 2017

Ralf Ficner

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23 December 2017

publication date

20 April 2008

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23 December 2017

Nature Structural & Molecular Biology

published in

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23 December 2017

volume

15

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23 December 2017

page(s)

435-443

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23 December 2017

issue

5

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23 December 2017

https://scigraph.springernature.com/pub.10.1038/nsmb.1415

exact match

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cites work

Pre-mRNA splicing: awash in a sea of proteins

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Mechanical devices of the spliceosome: motors, clocks, springs, and things

21 January 2018

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Sorting out the complexity of SR protein functions

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Multiple roles of arginine/serine-rich splicing factors in RNA processing.

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Mechanisms of alternative pre-messenger RNA splicing

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Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

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A pathway of sequential arginine-serine-rich domain-splicing signal interactions during mammalian spliceosome assembly

21 January 2018

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RS domain-splicing signal interactions in splicing of U12-type and U2-type introns.

21 January 2018

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Identification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factors

21 January 2018

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An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p

21 January 2018

1 reference

Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein

21 January 2018

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U1 snRNP-ASF/SF2 interaction and 5' splice site recognition: characterization of required elements.

21 January 2018

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Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

21 January 2018

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Selection of alternative 5' splice sites: role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1.

21 January 2018

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The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes

21 January 2018

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Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing

21 January 2018

1 reference

SR proteins and splicing control

21 January 2018

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Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.

21 January 2018

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Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.

21 January 2018

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A serine kinase regulates intracellular localization of splicing factors in the cell cycle

21 January 2018

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Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles

21 January 2018

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SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells

21 January 2018

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Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2

21 January 2018

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Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies

21 January 2018

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Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing

21 January 2018

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RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies

21 January 2018

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The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation

21 January 2018

1 reference

Identification of SRPK1 and SRPK2 as the major cellular protein kinases phosphorylating hepatitis B virus core protein

21 January 2018

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Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway

21 January 2018

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Characterisation of human and murine snRNP proteins by two-dimensional gel electrophoresis and phosphopeptide analysis of U1-specific 70K protein variants

21 January 2018

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The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP

21 January 2018

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A cold-sensitive mRNA splicing mutant is a member of the RNA helicase gene family

21 January 2018

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PRP28, a 'DEAD-box' protein, is required for the first step of mRNA splicing in vitro

21 January 2018

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

21 January 2018

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Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease

21 January 2018

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The SR protein SRp38 represses splicing in M phase cells

21 January 2018

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

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Cloning and characterization of an alternatively spliced form of SR protein kinase 1 that interacts specifically with scaffold attachment factor-B

21 January 2018

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Thiophosphorylation of U1-70K protein inhibits pre-mRNA splicing

21 January 2018

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Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism.

21 January 2018

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PP1/PP2A phosphatases are required for the second step of Pre-mRNA splicing and target specific snRNP proteins

31 March 2020

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Small-scale preparation of extracts from radiolabeled cells efficient in pre-mRNA splicing

31 March 2020

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Dynamics of protein isoelectric focusing in immobilized pH gradient gels

31 March 2020

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Isolation of an active step I spliceosome and composition of its RNP core.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB.1415

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23 December 2017

Dimensions Publication ID

0 references

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23 December 2017