(Q50336090)

5 March 2018

title

Isolation of an active step I spliceosome and composition of its RNP core. (English)

1 reference

5 March 2018

catalytic step 1 spliceosome

main subject

spliceosome

0 references

1 reference

U2-type catalytic step 1 spliceosome

GO:0071012

1 reference

U2-type catalytic step 2 spliceosome

GO:0071006

1 reference

U2-type precatalytic spliceosome

GO:0071007

1 reference

catalytic step 2 spliceosome

GO:0071005

1 reference

GO:0071013

precatalytic spliceosome

1 reference

GO:0071011

author

Reinhard Georg Lührmann

series ordinal

5

object named as

Reinhard Lührmann

1 reference

5 March 2018

3

Cindy L Will

1 reference

5 March 2018

4

Henning Urlaub

1 reference

5 March 2018

author name string

Sergey Bessonov

series ordinal

1

1 reference

5 March 2018

Maria Anokhina

series ordinal

2

1 reference

5 March 2018

language of work or name

English

0 references

publication date

5 March 2008

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5 March 2018

published in

Nature

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5 March 2018

volume

452

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5 March 2018

page(s)

846-850

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5 March 2018

issue

7189

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5 March 2018

https://scigraph.springernature.com/pub.10.1038/nature06842

exact match

0 references

cites work

The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

Mechanical devices of the spliceosome: motors, clocks, springs, and things

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Repositioning of the reaction intermediate within the catalytic center of the spliceosome.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Prp8 protein: at the heart of the spliceosome

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

The Prp19p-associated complex in spliceosome activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Bimolecular exon ligation by the human spliceosome

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Bimolecular exon ligation by the human spliceosome bypasses early 3' splice site AG recognition and requires NTP hydrolysis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

trans-splicing to spliceosomal U2 snRNA suggests disruption of branch site-U2 pairing during pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

The question remains: is the spliceosome a ribozyme?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

U2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06842

7 January 2021

Identifiers

DOI

10.1038/NATURE06842

1 reference

5 March 2018

Dimensions Publication ID

0 references

1 reference

5 March 2018