(Q28550639)

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Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs

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Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs (English)

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8

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Sanjay K Nigam

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author name string

Christopher Zhu

1

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Kabir B Nigam

2

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Rishabh C Date

3

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Kevin T Bush

4

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Stevan A Springer

5

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Milton H Saier

6

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Wei Wu

7

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publication date

2015

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10

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11

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e0140569

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copyright license

Creative Commons Attribution 4.0 International

4 November 2015

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April 2022 Public Data File from Crossref

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A Call for Systematic Research on Solute Carriers

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The organic anion transporter (OAT) family: a systems biology perspective

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19 March 2017

Organic anion transporters and their implications in pharmacotherapy.

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19 March 2017

The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization

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19 March 2017

Getting started in gene orthology and functional analysis

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19 March 2017

Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)

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19 March 2017

Clustal W and Clustal X version 2.0

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19 March 2017

Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation

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19 March 2017

Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

19 March 2017

Seeing chordate evolution through the Ciona genome sequence

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19 March 2017

Organic anion and cation transporters occur in pairs of similar and similarly expressed genes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

19 March 2017

Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

19 March 2017

Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

19 March 2017

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

19 March 2017

Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

19 March 2017

Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

19 March 2017

Molecular cloning and characterization of a novel liver-specific transport protein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

19 March 2017

Drug excretion mediated by a new prototype of polyspecific transporter

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

19 March 2017

Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

The EMBL-EBI bioinformatics web and programmatic tools framework.

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29 September 2017

What do drug transporters really do?

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29 September 2017

In vitro and in vivo radiosensitization of human glioma U251 cells induced by upregulated expression of SLC22A18.

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29 September 2017

The transporter classification database

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29 September 2017

BLAST: a more efficient report with usability improvements

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29 September 2017

The SLC22 family with transporters of organic cations, anions and zwitterions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Drug transport by Organic Anion Transporters (OATs).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

A role for the organic anion transporter OAT3 in renal creatinine secretion in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Differences in the substrate binding regions of renal organic anion transporters 1 (OAT1) and 3 (OAT3)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Expression and analysis of two novel rat organic cation transporter homologs, SLC22A17 and SLC22A23.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Interaction of organic cations with organic anion transporters

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Independent elaboration of steroid hormone signaling pathways in metazoans

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29 September 2017

Toward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

29 September 2017

A lamprey from the Devonian period of South Africa

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29 September 2017

A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport

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29 September 2017

Gene loss and evolutionary rates following whole-genome duplication in teleost fishes

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29 September 2017

Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20)

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29 September 2017

From 2R to 3R: evidence for a fish-specific genome duplication (FSGD).

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29 September 2017

Molecular phylogeny and divergence times of deuterostome animals

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29 September 2017

Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters

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29 September 2017

Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4633038

3 June 2018

An artificial intelligence approach to motif discovery in protein sequences: application to steriod dehydrogenases.

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3 June 2018

Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6).

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21 January 2018

Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0140569

21 January 2018

Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice.

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21 January 2018

Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0140569

21 January 2018

Xenobiotics and the evolution of multicellular animals: emergence and diversification of ligand-activated transcription factors

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0140569

21 January 2018

Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)].

1 reference

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21 January 2018

Physiology, structure, and regulation of the cloned organic anion transporters

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12 December 2020

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10.1371/JOURNAL.PONE.0140569

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Consolidated OpenCitations Corpus – April 2017

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2015PLoSO..1040569Z

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Consolidated OpenCitations Corpus – April 2017

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PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

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PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

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