(Q28550986)

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A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb's Release from 7SK snRNP

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29 February 2020

A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb's Release from 7SK snRNP (English)

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29 February 2020

natural product

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based on heuristic

inferred from title

Polygonum cuspidatum

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based on heuristic

inferred from title

6

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29 February 2020

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Cong Wang

1

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29 February 2020

Shuiyuan Yang

2

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29 February 2020

Huasong Lu

3

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29 February 2020

Hongchao You

4

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29 February 2020

Man Ni

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29 February 2020

Ting Lin

7

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29 February 2020

Xiang Gao

8

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29 February 2020

Haifeng Chen

9

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29 February 2020

Qiang Zhou

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29 February 2020

Yuhua Xue

11

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29 February 2020

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16 November 2015

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29 February 2020

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29 February 2020

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29 February 2020

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29 February 2020

e0142739

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29 February 2020

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Creative Commons Attribution 4.0 International

16 November 2015

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April 2022 Public Data File from Crossref

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0 references

Transcription-dependent association of multiple positive transcription elongation factor units to a HEXIM multimer

1 reference

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19 March 2017

Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription

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19 March 2017

7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

1 reference

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19 March 2017

Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription

1 reference

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19 March 2017

Tat-associated kinase (P-TEFb): a component of transcription preinitiation and elongation complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

19 March 2017

Control of RNA initiation and elongation at the HIV-1 promoter

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7 April 2017

Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.

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29 September 2017

Dynamics of HIV latency and reactivation in a primary CD4+ T cell model

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29 September 2017

AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

Viral-host interactions that control HIV-1 transcriptional elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

Botany, phytochemistry, pharmacology, and potential application of Polygonum cuspidatum Sieb.et Zucc.: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

Reactivation of latent HIV-1 by inhibition of BRD4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

RNA polymerase II elongation control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

The control of HIV transcription: keeping RNA polymerase II on track

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646521

29 September 2017

Short communication: activation of latent HIV type 1 gene expression by suberoylanilide hydroxamic acid (SAHA), an HDAC inhibitor approved for use to treat cutaneous T cell lymphoma

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29 September 2017

The challenge of finding a cure for HIV infection

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29 September 2017

Prevalence and pathogenesis of diabetes mellitus in HIV-1 infection treated with combined antiretroviral therapy

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29 September 2017

Eradication of HIV: current challenges and new directions

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29 September 2017

Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency

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29 September 2017

Non-AIDS-defining malignancies among HIV-infected patients in the highly active antiretroviral therapy era.

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29 September 2017

PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling

1 reference

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29 September 2017

HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription

1 reference

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29 September 2017

Modulation of a P-TEFb functional equilibrium for the global control of cell growth and differentiation

1 reference

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29 September 2017

HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.

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29 September 2017

Tannins and related compounds. XLVIII. Rhubarb. (7). Isolation and characterization of new dimeric and trimeric procyanidins

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3 June 2018

Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study

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Prostratin antagonizes HIV latency by activating NF-kappaB.

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Analgesic and anti-inflammatory effects of ethyl acetate fraction of Polygonum cuspidatum in experimental animals

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21 January 2018

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10.1371/JOURNAL.PONE.0142739

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29 February 2020

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29 February 2020

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