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The control of HIV transcription: keeping RNA polymerase II on track
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Europe PubMed Central
PMC publication ID
3478145
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
title
The control of HIV transcription: keeping RNA polymerase II on track
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3478145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
main subject
HIV
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author
Melanie Ott
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3478145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Matthias Geyer
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2
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Europe PubMed Central
PMC publication ID
3478145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author name string
Qiang Zhou
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3
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Europe PubMed Central
PMC publication ID
3478145
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
publication date
1 November 2011
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Europe PubMed Central
PMC publication ID
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retrieved
17 January 2020
published in
Cell Host & Microbe
1 reference
stated in
Europe PubMed Central
PMC publication ID
3478145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
10
1 reference
stated in
Europe PubMed Central
PMC publication ID
3478145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3478145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
426-435
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Europe PubMed Central
PMC publication ID
3478145
reference URL
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retrieved
17 January 2020
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Controlling the elongation phase of transcription with P-TEFb
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6 September 2017
The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter
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Cyclin-dependent kinase 9 (Cdk9) of fission yeast is activated by the CDK-activating kinase Csk1, overlaps functionally with the TFIIH-associated kinase Mcs6, and associates with the mRNA cap methyltransferase Pcm1 in vivo
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Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4
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6 September 2017
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
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6 September 2017
Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186
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6 September 2017
Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat
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6 September 2017
Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription
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6 September 2017
SIRT1 regulates HIV transcription via Tat deacetylation
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6 September 2017
Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression
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6 September 2017
Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor
1 reference
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PubMed Central
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6 September 2017
A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb
1 reference
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PubMed Central
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6 September 2017
Regulation of TAK/P-TEFb in CD4+ T lymphocytes and macrophages
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6 September 2017
Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA
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6 September 2017
Acetylation of the HIV-1 Tat protein: an in vitro study
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6 September 2017
A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter
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6 September 2017
HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.
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6 September 2017
Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain
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6 September 2017
HDAC6 is a microtubule-associated deacetylase
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6 September 2017
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
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6 September 2017
Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain
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6 September 2017
The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity
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6 September 2017
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
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6 September 2017
The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
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6 September 2017
Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
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6 September 2017
The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
6 September 2017
Structure and ligand of a histone acetyltransferase bromodomain
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
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6 September 2017
A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
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6 September 2017
P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
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6 September 2017
Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
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6 September 2017
The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
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6 September 2017
ELL2, a new member of an ELL family of RNA polymerase II elongation factors
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
6 September 2017
An RNA polymerase II elongation factor encoded by the human ELL gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
6 September 2017
Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
6 September 2017
HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
14 September 2017
Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
14 September 2017
Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
14 September 2017
The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
14 September 2017
Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
14 September 2017
Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
14 September 2017
Cdk9 T-loop phosphorylation is regulated by the calcium signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
23 June 2018
RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
23 June 2018
The proteasome regulates HIV-1 transcription by both proteolytic and nonproteolytic mechanisms.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
23 June 2018
HIV-1 tat transcriptional activity is regulated by acetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
23 June 2018
Specific interaction of the human immunodeficiency virus Tat proteins with a cellular protein kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
23 June 2018
A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
1 September 2018
Transient-mediated fate determination in a transcriptional circuit of HIV.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
1 September 2018
HIV-1 Tat is a natively unfolded protein: the solution conformation and dynamics of reduced HIV-1 Tat-(1-72) by NMR spectroscopy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
1 September 2018
VP16 and ubiquitin; binding of P-TEFb via its activation domain and ubiquitin facilitates elongation of transcription of target genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
1 September 2018
Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
1 September 2018
Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
1 September 2018
Tat acetylation regulates its actions on microtubule dynamics and apoptosis in T lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478145
retrieved
3 December 2018
Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22100159
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Arginine methylation of the HIV-1 nucleocapsid protein results in its diminished function
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22100159
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CHOM.2011.11.002
1 reference
stated in
Europe PubMed Central
PMC publication ID
3478145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Fatcat ID
release_czoktfgtdva3rbm72vswiifdoq
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/czoktfgtdva3rbm72vswiifdoq
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
3478145
1 reference
stated in
Europe PubMed Central
PMC publication ID
3478145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PubMed publication ID
22100159
1 reference
stated in
Europe PubMed Central
PMC publication ID
3478145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22100159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
ResearchGate publication ID
51814427
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