(Q46675052)

24 December 2017

title

Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA. (English)

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24 December 2017

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Ruichuan Chen

1

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24 December 2017

Zhiyuan Yang

series ordinal

2

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24 December 2017

Qiang Zhou

series ordinal

3

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24 December 2017

language of work or name

English

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publication date

19 November 2003

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24 December 2017

Journal of Biological Chemistry

published in

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24 December 2017

volume

279

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24 December 2017

page(s)

4153-4160

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24 December 2017

issue

6

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24 December 2017

DNA sequences complementary to human 7 SK RNA show structural similarities to the short mobile elements of the mammalian genome.

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1 reference

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Synthesis of two classes of small RNA species in vivo and in vitro.

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7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

21 January 2018

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The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

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Identification of multiple cyclin subunits of human P-TEFb

21 January 2018

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A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

21 January 2018

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CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo

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A highly purified RNA polymerase II elongation control system

21 January 2018

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Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

21 January 2018

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NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

21 January 2018

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Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo

21 January 2018

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Multifaceted activities of the HIV-1 transactivator of transcription, Tat.

21 January 2018

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P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

21 January 2018

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Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

21 January 2018

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MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner

21 January 2018

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Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells

21 January 2018

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Cell cycle regulatory proteins are targets for induced differentiation of transformed cells: Molecular and clinical studies employing hybrid polar compounds

21 January 2018

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Activation of human immunodeficiency virus type 1 by DNA damage in human cells

21 January 2018

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The transcriptional inhibitors, actinomycin D and alpha-amanitin, activate the HIV-1 promoter and favor phosphorylation of the RNA polymerase II C-terminal domain

21 January 2018

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Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy.

21 January 2018

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

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Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter

21 January 2018

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CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA

21 January 2018

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The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein

21 January 2018

1 reference

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Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310044200

Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

21 January 2018

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Principles of CDK regulation

21 January 2018

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Structural basis of cyclin-dependent kinase activation by phosphorylation

21 January 2018

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Dual phosphorylation of the T-loop in cdk7: its role in controlling cyclin H binding and CAK activity.

21 January 2018

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T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity

21 January 2018

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Identification of a novel isoform of Cdk9.

21 January 2018

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The role of Cdk7 in CAK function, a retro-retrospective

21 January 2018

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Transient induction of cyclin T1 during human macrophage differentiation regulates human immunodeficiency virus type 1 Tat transactivation function.

21 January 2018

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Nuclear protein phosphatase-1 regulates HIV-1 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310044200

Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310044200

A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310044200

21 January 2018

Identifiers

DOI

10.1074/JBC.M310044200

1 reference

24 December 2017

PubMed ID

14627702

1 reference

24 December 2017