(Q28552408)

2

0 references

Yangmei Deng

3

0 references

Xianxi Wang

4

0 references

Laura Raftery

5

0 references

Bert H O'Neil

6

0 references

Jen Jen Yeh

Creative Commons Attribution 4.0 International

7

0 references

language of work or name

English

0 references

publication date

2016

0 references

published in

PLOS One

0 references

volume

11

0 references

issue

1

0 references

page(s)

e0147113

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copyright license

start time

13 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Cancer statistics, 2010

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

19 March 2017

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Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase-Dependent Regulation of the Orphan Nuclear Receptor SHP

19 March 2017

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AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

19 March 2017

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AMPK: a nutrient and energy sensor that maintains energy homeostasis

19 March 2017

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7 April 2017

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The TOR pathway: a target for cancer therapy

7 April 2017

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Phase II trial of metformin and paclitaxel for patients with gemcitabine-refractory advanced adenocarcinoma of the pancreas

29 September 2017

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29 September 2017

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29 September 2017

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Circulating tumor cells as a biomarker of response to treatment in patient-derived xenograft mouse models of pancreatic adenocarcinoma.

29 September 2017

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Response to MLN8237 in pancreatic cancer is not dependent on RalA phosphorylation

29 September 2017

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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

29 September 2017

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Metformin improves healthspan and lifespan in mice

29 September 2017

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Cancer risk associated with use of metformin and sulfonylurea in type 2 diabetes: a meta-analysis

29 September 2017

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Metformin use is associated with better survival of diabetic patients with pancreatic cancer

29 September 2017

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Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells

29 September 2017

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A humanized anti-IGF-1R monoclonal antibody (R1507) and/or metformin enhance gemcitabine-induced apoptosis in pancreatic cancer cells

29 September 2017

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Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells.

29 September 2017

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AMPK and mTOR in cellular energy homeostasis and drug targets

29 September 2017

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AMP-activated protein kinase: nature's energy sensor

29 September 2017

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Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

29 September 2017

1 reference

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Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

29 September 2017

1 reference

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The impact of type 2 diabetes and antidiabetic drugs on cancer cell growth

29 September 2017

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Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner

29 September 2017

1 reference

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Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth

29 September 2017

1 reference

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New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes

29 September 2017

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LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711922

The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711922

Metformin induces apoptosis of pancreatic cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711922

Direct in vivo xenograft tumor model for predicting chemotherapeutic drug response in cancer patients

29 September 2017

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In vitro metformin anti-neoplastic activity in epithelial ovarian cancer.

29 September 2017

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The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711922

Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711922

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711922

Targeting AMPK in the treatment of malignancies.

29 September 2017

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0147113

AMPK and Raptor: matching cell growth to energy supply.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0147113

Adjuvant therapy of pancreatic cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711922

An in vivo platform for translational drug development in pancreatic cancer

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26760500

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sites of metformin-stimulated glucose metabolism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26760500

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Metformin and pancreatic cancer: a clue requiring investigation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26760500