(Q28561743)

NADPH-hemoprotein reductase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

nitric-oxide synthase activity

7 references

14 February 2019

Complete coding sequence of inducible nitric oxide synthase from human heart and skeletal muscle of patients with chronic heart failure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Inducible nitric oxide synthase expression of tumor and stromal cells is associated with the progression of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kappaB.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

2 references

1 reference

14 February 2019

Regulation of Sertoli-germ cell adherens junction dynamics in the testis via the nitric oxide synthase (NOS)/cGMP/protein kinase G (PRKG)/beta-catenin (CATNB) signaling pathway: an in vitro and in vivo study

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

cAMP-dependent protein kinase regulator activity

IPI

1 reference

14 February 2019

Attenuation of cAMP accumulation in adult rat cardiac fibroblasts by IL-1beta and NO: role of cGMP-stimulated PDE2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

oxidoreductase activity

iNOS regulation by calcium/calmodulin-dependent protein kinase II in vascular smooth muscle

protein kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

protein homodimerization activity

1 reference

14 February 2019

Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

Regulation of Sertoli-germ cell adherens junction dynamics in the testis via the nitric oxide synthase (NOS)/cGMP/protein kinase G (PRKG)/beta-catenin (CATNB) signaling pathway: an in vitro and in vivo study

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

nitric-oxide synthase binding

1 reference

14 February 2019

Regulation of Sertoli-germ cell adherens junction dynamics in the testis via the nitric oxide synthase (NOS)/cGMP/protein kinase G (PRKG)/beta-catenin (CATNB) signaling pathway: an in vitro and in vivo study

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

Heat shock regulates the respiration of cardiac H9c2 cells through upregulation of nitric oxide synthase

IPI

Hsp90 protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

Anti-inflammatory activities and mechanisms of action of the petroleum ether fraction of Rosa multiflora Thunb. hips

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

3 references

14 February 2019

Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular, and biochemical studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Evidence for a functional nitric oxide synthase system in brown adipocyte nucleus

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Peroxisomal localization of inducible nitric oxide synthase in hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular, and biochemical studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Evidence for a functional nitric oxide synthase system in brown adipocyte nucleus

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Peroxisomal localization of inducible nitric oxide synthase in hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

perinuclear region of cytoplasm

1 reference

14 February 2019

iNOS regulation by calcium/calmodulin-dependent protein kinase II in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

endothelial cell proliferation

biological process

1 reference

14 February 2019

Relationship between iNOS expression and aortic cell proliferation and apoptosis in an elastase-induced model of aorta aneurysm and the effect of 1400 W administration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

Relationship between iNOS expression and aortic cell proliferation and apoptosis in an elastase-induced model of aorta aneurysm and the effect of 1400 W administration

blood vessel remodeling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

arginine catabolic process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

superoxide metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

nitric oxide biosynthetic process

5 references

14 February 2019

Complete coding sequence of inducible nitric oxide synthase from human heart and skeletal muscle of patients with chronic heart failure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Association between the expression of inducible nitric oxide synthase by chondrocytes and its nitric oxide-generating activity in adjuvant arthritis in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

Attenuation of cAMP accumulation in adult rat cardiac fibroblasts by IL-1beta and NO: role of cGMP-stimulated PDE2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger

1 reference

14 February 2019

Attenuation of cAMP accumulation in adult rat cardiac fibroblasts by IL-1beta and NO: role of cGMP-stimulated PDE2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

nitric oxide mediated signal transduction

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

Endothelial dysfunction in the early- and late-stage type-2 diabetic Goto-Kakizaki rat aorta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

regulation of heart contraction

1 reference

14 February 2019

Cardiovascular responses and neurotransmitter changes during static muscle contraction following blockade of inducible nitric oxide synthase (iNOS) within the ventrolateral medulla

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

regulation of blood pressure

response to mechanical stimulus

2 references

1 reference

14 February 2019

Orthodontic force stimulates eNOS and iNOS in rat osteocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

Oxidative injury due to chronic nitric oxide synthase inhibition in rat: effect of regular exercise on the heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

glycoside metabolic process

1 reference

14 February 2019

Influence of N-methyl-D-aspartate receptors on ouabain activation of nuclear factor-κB in the rat hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

peptidyl-cysteine S-nitrosylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

Attenuation of cAMP accumulation in adult rat cardiac fibroblasts by IL-1beta and NO: role of cGMP-stimulated PDE2

cGMP-mediated signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

positive regulation of guanylate cyclase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

prostaglandin secretion

1 reference

14 February 2019

Effect of 17beta-estradiol on myocardial inducible NOS and endothelial NOS activities after ischemia-reperfusion in rat heart model

response to estradiol

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

response to tumor necrosis factor

1 reference

14 February 2019

TNF-alpha modulates iNOS expression in an experimental rat model of indomethacin-induced jejunoileitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

intracellular signal transduction

1 reference

14 February 2019

Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: role of p38 MAPK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

response to immobilization stress

1 reference

14 February 2019

Mangiferin decreases inflammation and oxidative damage in rat brain after stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

1 reference

14 February 2019

Upregulation of the production of interferon-γ and the gene expression of the inducible nitric oxide synthase after excimer laser ablation in rat corneas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

positive regulation of apoptotic process

1 reference

14 February 2019

iNOS enhances rat intestinal apoptosis after ischemia-reperfusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

negative regulation of blood pressure

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

regulation of protein kinase activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

retinoic acid receptor signaling pathway

1 reference

14 February 2019

Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

defense response to Gram-negative bacterium

1 reference

14 February 2019

Role of neuronal nitric oxide synthase and inducible nitric oxide synthase in intestinal injury in neonatal rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

cellular response to lipopolysaccharide

1 reference

14 February 2019

Antioxidative and anti-inflammatory effects of phenolic compounds from the roots of Ulmus macrocarpa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

cellular response to lithium ion

1 reference

14 February 2019

Effects of lithium on lipopolysaccharide-induced inflammation in rat primary glia cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

cellular response to vitamin D

1 reference

14 February 2019

1,25-Dihydroxyvitamin D3 prevented allergic asthma in a rat model by suppressing the expression of inducible nitric oxide synthase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

cellular response to cytokine stimulus

1 reference

14 February 2019

JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

cellular response to interleukin-1

1 reference

14 February 2019

Tetrandrine down-regulates ERK/NF-κB signaling and inhibits activation of mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

cellular response to tumor necrosis factor

1 reference

14 February 2019

Reciprocal regulation between proinflammatory cytokine-induced inducible NO synthase (iNOS) and connexin43 in bladder smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

cellular response to organic cyclic compound

1 reference

14 February 2019

JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

cellular response to redox state

1 reference

14 February 2019

Extracellular cysteine (Cys)/cystine (CySS) redox regulates metabotropic glutamate receptor 5 activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

response to dexamethasone

1 reference

14 February 2019

Biochemical and genetic alterations of oxidant/antioxidant status of the brain in rats treated with dexamethasone: protective roles of melatonin and acetyl-L-carnitine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518

regulation of cytokine production involved in inflammatory response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518